Blastomycosis

About the Disease
Blastomycosis, also known as north american blastomycosis, is related to adult respiratory distress syndrome and histoplasmosis, and has symptoms including skin lesions, lung lesions and pleural thickening. An important gene associated with Blastomycosis is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and Immune response IL-23 signaling pathway. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and lymph node, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Common Targets
NF-kappaB (NFkB)

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