Diabetic Macular Edema

About the Disease
Diabetic Macular Edema is related to vitreous detachment and retinal detachment. An important gene associated with Diabetic Macular Edema is VEGFA (Vascular Endothelial Growth Factor A), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. The drugs Dipivefrin and Diclofenac have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and retina, and related phenotypes are homeostasis/metabolism and nervous system

Common Targets
G5743 | G1432 | FLT1 | FLT4 | FECH | G4233 | KDR | CFD | TRPV4 | SIGMAR1 | BCR | NPM1 | ICAM1 | G598 | G3569 | Matrix Metalloproteinase (MMP) (nonspecified subtype) | TGFBR1 | Phospholipase A2 (nonspecified subtype) | HAFML | CCR2 | VEGFC | Integrin Receptor (nonspecified subtype) | G3480 | Tyrosine Kinase (nonspecified subtype) | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | AKR1B1 | G7124 | ANGPT2 | G7422 | FLT3 | RET | EPHB4 | PDE5A | Integrin alphavbeta5 receptor | RAF1 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | TEK | PDGFRA | JAK2 | ROBO4 | NF-kappaB (NFkB) | NMDA receptor | KIT | ACVR1 | ACVRL1 | LIPC | ROCK2 | JAK1 | JAK3 | DDIT4 | TGFB2 | Triacylglycerol Lipase (TG Lipase) (nonspecified subtype) | Proteasome Complex | CCR5 | MIR146A | PRKCB | Complement Complex | APEX1 | SRPK1 | G3576 | Integrin alphaLbeta2 (LFA-1) receptor | Janus Kinase (nonspecified subtype) | BDKRB1 | PTPRB | APOA1 | Transcriptional Enhancer Factor (TEAD) (nonspecified subype) | F11 | G596 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | ABL1 | KLKB1 | APOL1 | PTGER1 | PLA2G7 | CD19 | LIPE | PGF | Soluble guanylyl cyclase | SEMA3A | Integrin alphavbeta1 | HIF1A | CSF1R | PDGFRB | PTAFR | PTGFR | IRS1 | AOC3 | G2475 | LIPG | Collagenase (nonspecified subtype) | Integrin alpha2beta1 (VLA-2) receptor | F12 | G10413 | Innate Repair Receptor (IRR) | PPARA | LRRK2 | TYK2 | Na+/H+ Exchanger (NHE) (nonspecified subtype) | Integrin alphavbeta3 (vitronectin) receptor | Fibrinogen | Protein kinase C (nonspecified subtype) | NR3C1 | BABAM1 | Tyrosine-Protein Kinases Src (nonspecified subtype) | TRPV1

Note: If you'd like to get a target analysis report for Diabetic Macular Edema, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Diabetic Macular Edema at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Sarcoidosis | Muscular Dystrophy | Microphthalmia | Adenoma, Pleomorphic | Non-small Cell Lung Cancer | Hypoglycemia | Lipoma | Congenital Bilateral Absence Of Vas Deferens | Nail-Patella Syndrome | Schistosomiasis Mansoni | Fetal Akinesia Deformation Sequence | Oculodentodigital Dysplasia | Oligoastrocytoma | Osteogenesis Imperfecta Type III | Retinal Diseases | Periventricular Nodular Heterotopia | Hypoplastic Left Heart Syndrome | Premenstrual Syndrome | Focal Facial Dermal Dysplasia | DICER1 Syndrome | Rosacea | Hypopigmentation | Membranous Nephropathy | Familial Cerebral Amyloid Angiopathy | Cysticercosis | Choroideremia | Homocystinuria | Epidermal Nevus Syndrome | Ectodermal Dysplasia | Vitamin D Deficiency | Familial Isolated Hyperparathyroidism | Cardiomyopathy, Peripartum | Primary Hyperoxaluria | Encephalitis | Joubert Syndrome 2 | Riboflavin Transporter Deficiency Neuronopathy | Sulfite Oxidase Deficiency | Erythropoietic Protoporphyria | Neurodegeneration With Brain Iron Accumulation | Congenital Stromal Corneal Dystrophy | Early Infantile Epileptic Encephalopathy | Zimmermann-Laband Syndrome | Oculopharyngeal Muscular Dystrophy | Hypersomnia | Hypoalbuminemia | Goldenhar Syndrome | Asplenia | Atherosclerosis | Hyperprolactinemia | Chordoid Glioma | Hereditary Sensory And Autonomic Neuropathy | Nemaline Myopathy 8 | Chromosome 9q34.3 Deletion Syndrome | Patent Foramen Ovale | Hyperparathyroidism | Werner's Syndrome | Exostoses | Acute Motor Axonal Neuropathy | Congenital Aniridia | Wolcott-Rallison Syndrome | Androgen Insensitivity | Niemann-Pick Disease, Type A | Celiac Disease | Metabolic Diseases | Cancer, Breast | Amenorrhea | Globozoospermia | Ehlers-Danlos Syndrome | Primrose Syndrome | Leber Congenital Amaurosis | Stroke | Hyperparathyroidism-jaw Tumor Syndrome | Marshall-Smith Syndrome | Down Syndrome | Van Der Knaap Disease | Colitis, Microscopic | Arthropathy | Graves Disease | Myhre Syndrome | Hyperoxaluria | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Obesity | Agranulocytosis | Primary Familial Brain Calcification | Pseudomyxoma Peritonei | Botulism | Recurrent Respiratory Papillomatosis | Congenital Disorders Of Glycosylation Type II | Chronic Periodontitis | Syphilis | Pyelonephritis | Endocarditis | Keratopathy | Gingivitis | Retinal Degeneration | Rhabdomyosarcoma, Embryonal | Non-bullous Congenital Ichthyosiform Erythroderma | Genitopatellar Syndrome | Erectile Dysfunction | Menkes Disease | Weill-Marchesani Syndrome | McLeod Syndrome | Blastoma, Pleuropulmonary | Reye Syndrome | Corneal Ulcer | PHARC Syndrome | Hartnup Disease | Kaposi Sarcoma | Sepiapterin Reductase Deficiency | Cystitis, Interstitial | Encephalopathy | Addison Disease | Bullous Pemphigoid | Esophageal Adenocarcinoma | Spinocerebellar Ataxia | Iron Deficiency Anemia | GNE Myopathy | Relapsing Polychondritis | Optic Nerve Diseases | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Warsaw Breakage Syndrome | Motion Sickness | Neutropenia | Asthma, Nocturnal | Ganglioglioma | Discoid Lupus Erythematosus | Schnitzler Syndrome | Shock, Cardiogenic | Herpes Simplex Dermatitis | Osteoporosis-pseudoglioma Syndrome | Inflammatory Bowel Disease | Stomatitis | Nephronophthisis | Macular Corneal Dystrophy Type 1 | Eclampsia | Angioedema, Hereditary | Lymphoma, Follicular | Central Pain Syndrome | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Congenital Disorders Of Glycosylation | Glaucoma | Tardive Dyskinesia | Inflammatory Joint Disease | Hereditary Sensory Neuropathy Type 1 | Dystonia Musculorum Deformans | Endometritis | Hypobetalipoproteinemias | Spinocerebellar Ataxia Type 5 | Spinocerebellar Ataxia Type 20 | Beare-Stevenson Syndrome | Polyradiculopathy | Presbycusis | Polycystic Liver | Pemphigus | Vitreoretinopathy, Proliferative | Hamartoma | Myasthenia Gravis | Takenouchi-Kosaki Syndrome | Congenital Muscular Dystrophy | Meesmann Corneal Dystrophy | Familial Hypertrophic Cardiomyopathy | Multiple Epiphyseal Dysplasia | Hepatitis | Language Disorders | Axenfeld-Rieger Syndrome | Kabuki Syndrome | Polyneuropathy | Hodgkin Lymphoma | Neuropathy | Blue Nevus | Immunoproliferative Disorders | Thrombosis | Beta-Propeller Protein-associated Neurodegeneration | Basal Ganglia Disease, Biotin-responsive | Vitiligo | Keratocystic Odontogenic Tumor | Branchiootorenal Syndrome | Thalassemia | Melanoma, Malignant | Postpoliomyelitis Syndrome | Goiter, Nodular | Glomerulonephritis, Membranoproliferative | Cantu Syndrome | Peters-plus Syndrome | Encephalitis, Tick-borne | Nail Disorder, Nonsyndromic Congenital | Carcinoma, Squamous Cell | WAGR Syndrome | Optic Atrophy 2 | Photosensitivity | Neurofibromatosis-Noonan Syndrome | Glycogen Storage Disease Type 3 | Astrocytoma | Von Willebrand Disease | Hemorrhage | Joubert Syndrome | 3-methylglutaconic Aciduria Type I | Neuroblastoma | X-linked Myotubular Myopathy | Diabetes Mellitus, Transient Neonatal | Hypoparathyroidism | Hyperuricemia | Spinocerebellar Ataxia Type 23 | Metachromatic Leukodystrophy | Aldosterone Synthase Deficiency | Perry Syndrome | Charcot-Marie-Tooth Disease Type 4D | Pontocerebellar Hypoplasia | Azoospermia | Skin Carcinoma | Spondyloepiphyseal Dysplasia Tarda, X-linked | Enhanced S-cone Syndrome | Episodic Ataxia Type 2 | Osteosclerosis | Waardenburg Syndrome Type 1 | Bartsocas-Papas Syndrome | Granuloma Annulare | Hepatitis, Chronic | Hypercholesterolemia | Sensorineural Hearing Loss | Idiopathic Multicentric Castleman Disease | Focal Cortical Dysplasia Type 2 | Chanarin-Dorfman Syndrome | Hypertension, Pulmonary | X-linked Creatine Transporter Deficiency | Priapism | Creatine Deficiency Syndrome | MELAS Syndrome | Hyperlipidemia Type V | Hydrocephalus | Mucolipidosis | Osteochondroma | GM2-gangliosidosis AB Variant | Hyperacusis | Klippel-Feil Syndrome | Hyperlipidemia | Bernard-Soulier Syndrome | Feingold Syndrome | Ichthyosis, X-linked | Neuromuscular Disorders | Pneumoconiosis | Hepatorenal Syndrome | Ellis-Van Creveld Syndrome | Vitamin K Deficiency | Neurocysticercosis | Liver Diseases | Myositis | Sialidosis | Retinopathy Of Prematurity | Central Core Disease | Knobloch Syndrome | Giant Cell Arteritis | Charcot-Marie-Tooth Disease Type 2T | Cushing Syndrome | Arthritis, Psoriatic | Anxiety Disorders | Gynecomastia | Bronchitis | Chondrodysplasia Punctata 2, X-linked Dominant | Prolactinoma | Dystonia-parkinsonism, X-linked | Renal Tubular Acidosis | Chronic Idiopathic Myelofibrosis | Renal Medullary Carcinoma | Hypertension | Nephrocalcinosis | Mitochondrial Encephalomyopathy | Infantile Liver Failure Syndrome 1 | Plasma Cell Dyscrasia | Tonsillitis | Pemphigus Vulgaris | Rift Valley Fever | Autoimmune Disease | Optic Neuropathy, Anterior Ischemic | Syncope | Aldosterone Deficiency | Distal Spinal Muscular Atrophy | Hemimegalencephaly | Ebstein Anomaly | Hemangioblastoma | Wolman Disease | Kidney Stones | Pancreatitis, Chronic | Filariasis | Sick Sinus Syndrome 1 | Trigonocephaly | Carcinoma, Transitional Cell | Familial Hemiplegic Migraine | Avian Influenza | Intermittent Claudication | Pulverulent Zonular Cataract | Transient Bullous Dermolysis Of The Newborn | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Cholera | Common Variable Immunodeficiency | Methylmalonic Acidemia | Patent Ductus Arteriosus | Sezary Syndrome | Meningioma | Pancreatitis | Microphthalmia, Syndromic 7 | Herpes Genitalis | Lateral Meningocele Syndrome | Retinitis Pigmentosa | Arts Syndrome | Leber Hereditary Optic Neuropathy | Poretti-Boltshauser Syndrome | Pleural Tuberculosis | Otopalatodigital Syndrome Type 2 | Epilepsy Of Infancy With Migrating Focal Seizures | Hypertension, Renal | Skin Fragility-woolly Hair Syndrome | Ligneous Conjunctivitis | Pityriasis Rubra Pilaris | Hepatopulmonary Syndrome | Fundus Albipunctatus | Aneurysm, Thoracic Aortic | Thyroid Hormone Resistance | Pemphigoid | Agnathia-Otocephaly Complex | Acute Lung Injury | Inflammatory Myofibroblastic Tumor | Cyst | Impulse Control Disorder | Dengue Shock Syndrome | Hereditary Hemorrhagic Telangiectasia | Renpenning Syndrome | Poirier-Bienvenu Neurodevelopmental Syndrome | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Spinocerebellar Ataxia Type 10 | Retinopathy, Diabetic | Loeys-Dietz Syndrome | Measles | Greenberg Dysplasia | Premature Ejaculation | Renal Dysplasia | Hepatitis E | Facioscapulohumeral Muscular Dystrophy | Primary Sclerosing Cholangitis | Usher Syndrome Type IIC | Frontometaphyseal Dysplasia | Cutaneous Angiosarcoma | Ocular Surface Squamous Neoplasia | Thyroid Dyshormonogenesis | Antley-Bixler Syndrome | Alopecia | Liver Failure | Rolandic Epilepsy | Hypothalamic Obesity | Granular Corneal Dystrophy | Alpha-1 Antitrypsin Deficiency | Obsessive-compulsive Disorder | Leukoencephalopathy, Progressive Multifocal | GLUT1 Deficiency Syndrome | Meningitis | Alkaptonuria | Bartter Syndrome | COACH Syndrome | Congenital Sodium Diarrhea | Blood Protein Disorders | Chromosome 8q21.11 Deletion Syndrome | LEOPARD Syndrome | Opisthorchiasis | Corneal Dystrophy | Pneumonia, Viral | X-linked Acrogigantism | Peripheral Neuropathy | Chediak-Higashi Syndrome | Toxoplasmosis | Progressive Osseous Heteroplasia | Urticaria | Congenital Hemolytic Anemia | Lymphangiomatosis | Panuveitis | Pontocerebellar Hypoplasia Type 7 | Hypotension, Orthostatic | Keratosis, Seborrheic | Primary Aldosteronism | Metanephric Adenoma | Hypohidrotic Ectodermal Dysplasia | Epidermolysis Bullosa | Atelosteogenesis Type 1 | Spinal Muscular Atrophy Type 3 | Postpartum Depression | Waardenburg Syndrome Type 2E | Paraganglioma | Gastroenteritis, Eosinophilic | Oligoasthenoteratozoospermia | Polymyositis | Myopia | Senior-Loken Syndrome | Rheumatoid Arthritis | Chordoma | Mumps | Thrombasthenia | Stroke, Ischemic | Tinea | Japanese Encephalitis | Gerodermia Osteodysplastica | Hyperkeratosis