Arts Syndrome

About the Disease
Arts Syndrome, also known as arts, is related to charcot-marie-tooth disease type 5 and urolithiasis, and has symptoms including ataxia, seizures and unspecified visual loss. An important gene associated with Arts Syndrome is PRPS1 (Phosphoribosyl Pyrophosphate Synthetase 1), and among its related pathways/superpathways are Metabolism and Metabolism of nucleotides. The drugs Sirolimus and Tangerine have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and kidney, and related phenotypes are optic atrophy and blindness

Common Targets
PRPS1

Note: If you'd like to get a target analysis report for Arts Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Arts Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Pyruvate Kinase Deficiency | Retinal Dystrophy | Glycogen Storage Disease Type 5 | Progressive Encephalopathy-optic Atrophy Syndrome | LEOPARD Syndrome | Pneumoconiosis | Vitamin K Deficiency | Pheochromocytoma | Insulinoma | Alexander Disease | Feingold Syndrome | Leishmaniasis, Visceral | Spinocerebellar Ataxia Type 1 | Gallstones | Congenital Bile Acid Synthesis Defect | Gastritis, Atrophic | Hepatitis, Autoimmune | Alopecia | Meesmann Corneal Dystrophy | Niemann-Pick Disease, Type C | Papulopustular Rosacea | Schamberg Disease | Hypotension, Orthostatic | Stomatitis | Metatropic Dysplasia | Blepharophimosis Syndrome | Granular Corneal Dystrophy | Glioblastoma Multiforme | Bicuspid Aortic Valve | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Paroxysmal Kinesigenic Dyskinesia | CREST Syndrome | 3-methylcrotonyl-CoA Carboxylase Deficiency | Aarskog-Scott Syndrome | Narcolepsy | Hoyeraal-Hreidarsson Syndrome | Pfeiffer Syndrome | Ebstein Anomaly | Coloboma | Angiodysplasia | Hypertension, Renovascular | Neurodegeneration With Brain Iron Accumulation | Metachondromatosis | Rosacea | Chronic Lymphocytic Leukemia | Zollinger-Ellison Syndrome | Autonomic Neuropathy | Hyperbilirubinemia | Angiosarcoma | Amyloidosis | Uveitis, Anterior | Cardiomyopathy, Peripartum | Dyggve-Melchior-Clausen Disease | Thrombotic Microangiopathy | Mastitis | Spinocerebellar Ataxia Type 10 | Familial Exudative Vitreoretinopathy | Distal Myopathy | Wiedemann-Steiner Syndrome | Hereditary Xerocytosis | Waardenburg Syndrome | Acquired Partial Lipodystrophy | Urea Cycle Disorder | Bloom Syndrome | Behcet's Disease | Beare-Stevenson Syndrome | Takayasu's Arteritis | CDKL5 Deficiency Disorder | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Lipoma | Oguchi Disease-2 | Stiff-man Syndrome | Neurocutaneous Syndromes | Potocki-Shaffer Syndrome | Colitis, Collagenous | Neurofibroma | Oculodentodigital Dysplasia | Veno-occlusive Disease | Osteosarcoma | Spermatocele | Atrioventricular Septal Defect | Prune Belly Syndrome | Pupil Disorders | Split Hand-foot Malformation | Epidermolysis Bullosa Acquisita | Sclerosteosis 2 | Lichen Sclerosus | Lesch-Nyhan Syndrome | Meningeal Melanocytoma | Deafness, Dystonia, And Cerebral Hypomyelination | Desmosterolosis | Focal Facial Dermal Dysplasia | Bardet-Biedl Syndrome | GNE Myopathy | X-linked Acrogigantism | Eosinophilia | Mabry Syndrome | Bullous Pemphigoid | Coronary Artery Disease | Hyperlipidemia, Familial Combined | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Methemoglobinemia | Low Phospholipid Associated Cholelithiasis | Sarcoidosis | Von Willebrand Disease | Antiphospholipid Syndrome | Sorsby Fundus Dystrophy | Carbohydrate Metabolism Disorders | Patent Ductus Arteriosus | Melanoma, Uveal | Congenital Hereditary Endothelial Dystrophy Type I | Kearns-Sayre Syndrome | Congenital Absence Of Vas Deferens | Cancer, Lung | Cancer, Prostate | Colitis, Lymphocytic | Neutrophilia | Muir-Torre Syndrome | Toxoplasmosis | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Agoraphobia | Scabies | Borderline Personality Disorder | Trichuriasis | Hashimoto Thyroiditis | Irritable Bowel Syndrome | Carcinoid Tumor | Postpoliomyelitis Syndrome | Rickets | Spinocerebellar Ataxia Type 12 | Spinocerebellar Ataxia Type 7 | Adrenal Insufficiency | Retinal Coloboma | Choroideremia | Unverricht-Lundborg Syndrome | Pseudo-pseudohypoparathyroidism | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Trimethylaminuria | Atherosclerosis | Lafora Disease | Vaginitis | GATA2 Deficiency | Autoimmune Autonomic Ganglionopathy | Long QT Syndrome Type 3 | Fetal And Neonatal Alloimmune Thrombocytopenia | Hernia, Inguinal | Chronic Enteropathy Associated With SLCO2A1 Gene | Sturge-Weber Syndrome | Neural Tube Defect | Carcinoma, Merkel Cell | Craniolenticulosutural Dysplasia | Vertigo | Congenital Dysfibrinogenemia | Takotsubo Cardiomyopathy | Cocaine-Related Disorders | Schistosomiasis | Enlarged Vestibular Aqueduct | Congenital Bilateral Absence Of Vas Deferens | 3C Syndrome | Angioedema, Acquired | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Pneumonia, Bacterial | Meningioma, Benign | Fanconi Syndrome | Juvenile Xanthogranuloma | Temtamy Preaxial Brachydactyly Syndrome | Cardiospondylocarpofacial Syndrome | Dent Disease | Basal Ganglia Disease | Opisthorchiasis | Myoclonic Epilepsy With Ragged Red Fibers | Varicocele | Polyarteritis Nodosa | Postaxial Polydactyly | Pulmonary Alveolar Proteinosis | WAGR Syndrome | Patent Foramen Ovale | Glucagonoma | Facioscapulohumeral Muscular Dystrophy Type 1 | Tibial Muscular Dystrophy | Joubert Syndrome 2 | Cyst | Thrombophlebitis | Sarcoma, Ewing | Fibromuscular Dysplasia | Trigonocephaly | Albinism | Polydactyly | Bone Giant Cell Tumor | Connective Tissue Disorders | Charcot-Marie-Tooth Disease, Type 2A | Pseudohypoparathyroidism Type 1C | Mucolipidosis Type III | Norrie Disease | Gastroschisis | Asthma, Exercise-induced | Corneal Dystrophy | Harlequin Ichthyosis | Ornithine Transcarbamylase Deficiency | Pneumothorax | Infantile Refsum Disease | Empyema | Ehlers-Danlos Syndrome | Protein S Deficiency | Cluster Headache | Schizencephaly | Histiocytic Sarcoma | Congenital Tufting Enteropathy | Epidermolysis Bullosa Simplex, Localized | Agranulocytosis | Acrocallosal Syndrome | Systemic Mastocytosis | Hyperuricemia | Globozoospermia | Preaxial Polydactyly | Follicular Dendritic Cell Sarcoma | Persistent Truncus Arteriosus | Postpartum Depression | Frontotemporal Dementia | Hamartoma | Infantile Liver Failure Syndrome 1 | Light Chain Amyloidosis | Spondyloperipheral Dysplasia | Diabetes Gestational | Anorexia Nervosa | Weill-Marchesani Syndrome | Gray Platelet Syndrome | Asperger Syndrome | Neuroleptic Malignant Syndrome | Arthritis | Plasma Cell Dyscrasia | Benign Familial Pemphigus | Prolidase Deficiency | Hereditary Hemorrhagic Telangiectasia Type 2 | Intellectual Disability, Autosomal Dominant 5 | Fetal Akinesia Deformation Sequence | Acute Tubular Necrosis | Epilepsy Of Infancy With Migrating Focal Seizures | Renal-hepatic-pancreatic Dysplasia | NGLY1 Deficiency | Encephalitis, Tick-borne | Milk Allergy | Treacher Collins Syndrome | Hyperthermia, Malignant | Teratozoospermia | Paraganglioma, Carotid Body | Wiskott-Aldrich Syndrome | Hereditary Elliptocytosis | Trichotillomania | Hypervalinemia | Hydronephrosis | Cousin Syndrome | Hypotrichosis Simplex | Blastomycosis | CHOPS Syndrome | Cleidocranial Dysplasia | Chondrodysplasia Punctata 2, X-linked Dominant | Esotropia | Sponastrime Dysplasia | Retinal Diseases | Pemphigus Vulgaris | Analgesia | Peroxisomal Disorder | Multiple Sclerosis, Relapsing-remitting | Oculocutaneous Albinism | Synovitis | Tuberculosis | Chordoma | Nail-Patella Syndrome | Keratocystic Odontogenic Tumor | Polycystic Ovary Syndrome | Thrombosis | Dwarfism | Pitt-Hopkins Syndrome | Congenital Lipoid Adrenal Hyperplasia | Fibrosis | Cutaneous Angiosarcoma | Exostoses | H Syndrome | Apert Syndrome | Meniere's Disease | Senior-Loken Syndrome | Epidermolysis Bullosa | Periventricular Nodular Heterotopia | Osteopetrosis | Spinocerebellar Ataxia Type 15 | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Supravalvular Aortic Stenosis | Alpha-1 Antitrypsin Deficiency | Hypertension, Renal | Torticollis | Restrictive Dermopathy | Enhanced S-cone Syndrome | Bacterial Meningitis | Stromal Corneal Dystrophy | Primary Torsion Dystonia | Diabetes Insipidus | Wolff-Parkinson-White Syndrome | Glomerulonephritis | Nicotine Dependence | Neuromyotonia | SAPHO Syndrome | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Chylothorax, Congenital | Hemolytic Uremic Syndrome, Atypical | Melanoma, Malignant | Neurofibromatosis Type 1 | Primary Progressive Aphasia | Barrett Esophagus | Absence Epilepsy | Molybdenum Cofactor Deficiency | Coffin-Lowry Syndrome | Primary Aldosteronism | Urofacial Syndrome | Myositis | Epidermolytic Palmoplantar Keratoderma | Aldosterone Deficiency | Dystonia | Lymphomatoid Granulomatosis | Dementia | Gerstmann-Straussler-Scheinker Syndrome | Autonomic Nervous System Disorders | Leiomyosarcoma | Adenylosuccinate Lyase Deficiency | Familial Mediterranean Fever | Pachyonychia Congenita | Pelizaeus-Merzbacher Disease | Smoldering Myeloma | Craniofacial Dysostosis | Hemolytic Uremic Syndrome | Acute Leukemia | Skin Fragility-woolly Hair Syndrome | Jalili Syndrome | Pseudohypoparathyroidism Type 1A | Hypertensive Nephropathy | Canavan Disease | Combined Deficiency Of Factor V And Factor VIII | Nance-Horan Syndrome | Uveitis | Non-Hodgkin Lymphoma | Autoimmune Hemolytic Anemia | Meconium Ileus | Cri-du-chat Syndrome | Hypermethioninemia | Hereditary Spherocytosis | Williams Syndrome | Saul-Wilson Syndrome | Lateral Meningocele Syndrome | Trichomegaly | Spinal Cord Diseases | Diarrhea | Roberts Syndrome | Hartsfield Syndrome | Hypocalcemia | Robinow Syndrome | Cerebellofaciodental Syndrome | Galactosemia | Tay-Sachs Disease | Sclerosteosis | Fabry's Disease | Cryptorchidism | Bronchiolitis | Majeed Syndrome | Huntington's Disease | Renpenning Syndrome | T-cell Prolymphocytic Leukemia | Tic Disorder | Cardiomyopathy, Hypertrophic | Inflammatory Joint Disease | Psoriasis | Osteogenesis Imperfecta Type V | Osteomyelitis | Pure Red Cell Aplasia | Rheumatoid Arthritis | Sialidosis | Papillorenal Syndrome | Hypercholesterolemia | Tyrosine Hydroxylase Deficiency | Anencephaly | Hypersomnia | Measles | Fatty Aldehyde Dehydrogenase Deficiency | Filariasis | Osteogenesis Imperfecta Type II | Specific Granule Deficiency | Endometritis | Macrophage Activation Syndrome | Acute Kidney Injury | Rash | Carcinoma, Small Cell | Twin-to-twin Transfusion Syndrome | Dysgerminoma | Tendinopathy | Porphyria Cutanea Tarda | Acute Coronary Syndrome | Encephalopathy, Ethylmalonic | Thyroiditis, Autoimmune | Dengue Hemorrhagic Fever | Calcium Pyrophosphate Deposition Disease