Absence Epilepsy

About the Disease
Childhood Absence Epilepsy, also known as pyknolepsy, is related to juvenile absence epilepsy and epilepsy, idiopathic generalized, and has symptoms including seizures, absence attacks and absence seizures. An important gene associated with Childhood Absence Epilepsy is PCDH19 (Protocadherin 19), and among its related pathways/superpathways are CREB Pathway and Sweet Taste Signaling. The drugs Cannabidiol and Anticonvulsants have been mentioned in the context of this disorder. Affiliated tissues include eye, thalamus and temporal lobe, and related phenotypes are eeg with spike-wave complexes (2.5-3.5 hz) and typical absence seizure

Common Targets
Calcium channel (nonspecified subtype) | SCN3A | GABRG2 | BRD2 | NIPA2 | CACNA1G | G5243 | PRRT2 | GRIN2A | GABRB3 | LOC105371465 | SLC2A1 | GABRA5 | KCNJ10 | CACNA1I | SV2A | CACNA1H | CACNA2D1

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