Eosinophilic Gastroenteritis

About the Disease
Eosinophilic Gastroenteritis, also known as eosinophilic enteritis, is related to omenn syndrome and peptic esophagitis. An important gene associated with Eosinophilic Gastroenteritis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Bisacodyl and Ondansetron have been mentioned in the context of this disorder. Affiliated tissues include small intestine, colon and liver, and related phenotypes are eosinophilia and dysphagia

Common Targets
G2475 | SIGLEC8 | Integrin alpha4beta7 (LPAM-1) receptor | 15-Lipoxygenase (nonspecified subtype) | CCR5 | IL5RA | Proteasome Complex | IL13 | CD19 | ALOX15

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