Smoldering Myeloma

About the Disease
Smoldering Myeloma is related to immunoglobulin light chain amyloidosis and chromosome 13q14 deletion syndrome, and has symptoms including bone pain An important gene associated with Smoldering Myeloma is MYOM2 (Myomesin 2), and among its related pathways/superpathways are NF-kappaB Signaling and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. The drugs Daratumumab and Ichthammol have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and temporal lobe, and related phenotypes are immune system and hematopoietic system

Common Targets
G29126 | Killer Cell Immunoglobulin-Like Receptor (KIR) (nonspecified subtype) | G7124 | DKK1 | CD38 | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | Proteasome Complex | CRBN | G5133 | HDAC6

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