Sertoli Cell-only Syndrome
Sertoli Cell-only Syndrome
About the Disease
Spermatogenic Failure, X-Linked, 1, also known as sertoli cell-only syndrome, is related to testicular cancer and testicular disease. An important gene associated with Spermatogenic Failure, X-Linked, 1 is CFAP47 (Cilia And Flagella Associated Protein 47), and among its related pathways/superpathways is Male infertility. Affiliated tissues include Testis, testes and pituitary, and related phenotypes are obesity and gynecomastia
Common Targets
DMRT1 | FSHR | HELQ | DICER1 | G367 | FSHB
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Snyder-Robinson Syndrome | Growth Hormone Excess | Rickets | Mucormycosis | Ataxia-ocular Apraxia 2 | Oguchi Disease-2 | Pituitary Disorders | Strabismus | Blepharo-cheilo-odontic Syndrome | Myotonia | Familial Mediterranean Fever | Multicystic Renal Dysplasia | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Primary Carnitine Deficiency | Retinal Degeneration | Demyelinating Diseases | Trismus-pseudocamptodactyly Syndrome | VACTERL/VATER Association | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Megaloblastic Anemia | Diabetes Gestational | Hemimegalencephaly | Hepatic Veno-occlusive Disease | Still Disease | Haim-Munk Syndrome | Dwarfism | Persistent Hyperplastic Primary Vitreous | Fucosidosis | Cocaine-Related Disorders | Withdrawal Syndrome | Diabetes Insipidus, Nephrogenic | Ischemia | Cutaneous T-cell Lymphoma | Vitamin D Deficiency | Autoimmune Disease | Protein S Deficiency | Azoospermia | Photosensitivity | Usher Syndrome Type IIC | Polycystic Liver | Chudley-McCullough Syndrome | Facioscapulohumeral Muscular Dystrophy Type 2 | Split Hand-foot Malformation | Hereditary Neuropathy With Liability To Pressure Palsies | Wiedemann-Steiner Syndrome | Prediabetes | Dyskeratosis Congenita | Otosclerosis | Infantile Spasm | Erythropoietic Protoporphyria | Bursitis | Hyperandrogenemia | Gout | Osteosarcoma | Thrombotic Microangiopathy | Neuromyotonia | Myelitis | Camurati-Engelmann Disease | Benign Hereditary Chorea | Pigment Dispersion Syndrome | Sensorineural Hearing Loss | Inflammatory Myofibroblastic Tumor | Methemoglobinemia | Nephrotic Syndrome | Asperger Syndrome | Renal-hepatic-pancreatic Dysplasia | Neurofibroma | Multiple Sclerosis | Sarcomatoid Carcinoma Of The Lung | Congenital Dyserythropoietic Anemia Type 1 | Charcot-Marie-Tooth Disease, Type 1A | Double Outlet Right Ventricle | Desbuquois Syndrome | Coronary Artery Disease | Spinocerebellar Ataxia Type 14 | Zygomycosis | Ichthyosis | Tularemia | AIDS | Anti-NMDA Receptor Encephalitis | Hypoparathyroidism | Xeroderma Pigmentosum | Meleda Disease | PASLI Disease | Gastritis | Cri-du-chat Syndrome | Pompe Disease | Major Depression | Seizures-scoliosis-macrocephaly Syndrome | Papilledema | Rhinitis | Overactive Bladder | Hereditary Sensory And Autonomic Neuropathy | DiGeorge Syndrome | Dermatomyositis | Sengers Syndrome | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Holoprosencephaly | Nail Disorder, Nonsyndromic Congenital | Sponastrime Dysplasia | Pelvic Inflammatory Disease | Chanarin-Dorfman Syndrome | Metaphyseal Chondrodysplasia, Schmid Type | Prune Belly Syndrome | Lipoma | LEOPARD Syndrome | Epidermal Nevus Syndrome | Parkinson's Disease | Ectopia Lentis, Isolated, Autosomal Recessive | Congenital Ichthyosiform Erythroderma | Mosaic Variegated Aneuploidy Syndrome 2 | Autism | Lymphangioleiomyomatosis | Hyperhomocysteinemia | Relapsing Polychondritis | Transthyretin-related Amyloidosis | Frank-ter Haar Syndrome | Disseminated Intravascular Coagulation | Osteoarthritis | 3-methylglutaconic Aciduria Type IV | Focal Segmental Glomerulosclerosis | Craniosynostosis | Hypokalemic Periodic Paralysis | Cerebral Cavernous Malformations | Leber Hereditary Optic Neuropathy | Pyruvate Kinase Deficiency | Isobutyryl-CoA Dehydrogenase Deficiency | Thrombocythemia, Essential | Systemic Mastocytosis | Premature Ejaculation | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Encephalitis | Erythema Multiforme | Multicentric Carpotarsal Osteolysis Syndrome | 3-methylglutaconic Aciduria Type I | Chorioretinitis | Krabbe Disease | Kashin-Beck Disease | Schnyder Crystalline Corneal Dystrophy | Syphilis | Paroxysmal Kinesigenic Dyskinesia | Lymphopenia | Congenital Poikiloderma | Adenoma, Villous | Meconium Ileus | Thin Basement Membrane Disease | Oligoasthenoteratozoospermia | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Heterotopic Ossification | Chronic Idiopathic Myelofibrosis | Anorectal Malformations | Lassa Fever | Gaucher Disease | Exocrine Pancreatic Insufficiency | COACH Syndrome | Epidermolytic Palmoplantar Keratoderma | Geleophysic Dysplasia | Periodic Limb Movement Disorder | Amebiasis | Brooke-Spiegler Syndrome | Pendred Syndrome | Acute Kidney Injury | Tetanus | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Open-angle Glaucoma | Mitochondrial Encephalomyopathy | Ulcerative Colitis | DOCK8 Immunodeficiency Syndrome | Light Chain Amyloidosis | Mitochondrial Myopathy | Hemangioendothelioma | Aneurysm, Abdominal Aortic | Imerslund-Grasbeck Syndrome | Diabetic Nephropathy | Hypokalemia | Irritable Bowel Syndrome | Joubert Syndrome 2 | Congenital Disorders Of Glycosylation | Polycystic Kidney, Autosomal Dominant | Nemaline Myopathy 8 | Hypersomnia | Hypophosphatasia | Antley-Bixler Syndrome | Angiodysplasia | Giant Cell Glioblastoma | Purpura | Asthma | Argininosuccinic Aciduria | Pituitary Stalk Interruption Syndrome | Albinism | Multiple Sulfatase Deficiency | Hyperparathyroidism, Primary | Myofibrillar Myopathy | Spinocerebellar Ataxia Type 20 | Tendinopathy | Diastrophic Dysplasia | Melanoma, Uveal | Maple Syrup Urine Disease | Trichomegaly | Diverticulitis | Pontocerebellar Hypoplasia | Chordoid Glioma | Chondromyxoid Fibroma | Shprintzen-Goldberg Syndrome | Tenosynovial Giant Cell Tumor | Rubinstein-Taybi Syndrome | Thymoma, Malignant | Familial Partial Lipodystrophy | Sick Sinus Syndrome 1 | Temporal Lobe Epilepsy | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Cholera | Hypothalamic Obesity | Familial Pheochromocytoma-paraganglioma | Poikiloderma With Neutropenia | Congestive Heart Failure | Blepharitis | Wolman Disease | Colitis, Collagenous | Charcot-Marie-Tooth Disease Type 2D | Osteochondroma | Fabry's Disease | Hyperparathyroidism, Secondary | Angioimmunoblastic T-cell Lymphoma | Keratosis, Actinic | Proximal Symphalangism | Anemia | Vertebrobasilar Insufficiency | Hypotonia-cystinuria Syndrome | Hydronephrosis | Adenosine Deaminase 2 Deficiency | Glycogen Storage Disease Type 3 | Vertigo | L-2-Hydroxyglutaric Aciduria | Antithrombin III Deficiency | Schizophrenia | Scapuloperoneal Spinal Muscular Atrophy | Glycogen Storage Disease Type 1a | Diabetic Encephalopathy | Hemochromatosis Type 2 | Meier-Gorlin Syndrome | Sleep Disorder | Cholecystitis | Dominant Optic Atrophy | Premenstrual Syndrome | Communication Disorders | Cornelia De Lange Syndrome | Influenza | Cancer, Lung | Hypertensive Nephropathy | Sepiapterin Reductase Deficiency | Urofacial Syndrome | Neovascular Glaucoma | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Chondrodysplasia Punctata 2, X-linked Dominant | Fuchs Dystrophy | Spinal Muscular Atrophy Type 2 | Hennekam Lymphangiectasia-lymphedema Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Alveolar Capillary Dysplasia | Choriocarcinoma | Leishmaniasis, Visceral | Astrocytoma, Anaplastic | Cirrhosis | Osteogenesis Imperfecta Type V | Chronic Granulomatous Disease | Optic Neuritis | Nutrition Disorders | Nicolaides-Baraitser Syndrome | 3-M Syndrome | Hypotrichosis Simplex | Sporadic Hemiplegic Migraine | Cancer, Skin | Glaucoma | Retinal Dystrophy | Hypertension, Pulmonary | Acute Leukemia | Acromicric Dysplasia | Tetraplegia | Pseudohypoparathyroidism Type 2 | Androgenic Alopecia | Primary Ovarian Insufficiency | Fibronectin Glomerulopathy | Myeloid Leukemia | Histiocytosis | Acrodysostosis | Smith-Kingsmore Syndrome | Carpenter Syndrome | Hypervalinemia | Glycogen Storage Disease Type 5 | Subcortical Band Heterotopia | Pulmonary Stenosis | Carcinoma, Squamous Cell | Hypolipoproteinemia | Cyclic Vomiting Syndrome | Pontocerebellar Hypoplasia Type 7 | Glutaric Aciduria Type 2 | Chorea | Colorectal Adenoma | Adenosine Deaminase Deficiency | Tyrosine Hydroxylase Deficiency | Zimmermann-Laband Syndrome | Hypopituitarism | Tyrosinemia Type 1 | Skin Carcinoma | Palsy, Cerebral | Polyomavirus Nephropathy | Raine 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| Chronic Periodontitis | Spinocerebellar Ataxia Type 5 | Keratoacanthoma | Congenital Dyserythropoietic Anemia Type 4 | Polydactyly | Familial Cerebral Amyloid Angiopathy | Nail-Patella Syndrome | Nasodigitoacoustic Syndrome | Obesity, Morbid | Kaposi Sarcoma | Triphalangeal Thumb-polysyndactyly Syndrome | Autonomic Neuropathy | Fibrosarcoma