Disease

Oligodendroglioma

About the Disease
Glioma Susceptibility 1, also known as astrocytoma, is related to childhood brain stem glioma and chordoid glioma, and has symptoms including headache and seizures. An important gene associated with Glioma Susceptibility 1 is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Transcription_Transcription factor Tubby signaling pathways and Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome. The drugs Dabrafenib and Trametinib have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and t cells, and related phenotypes are astrocytoma and ependymoma

Common Targets
G3845 | NTRK1 | CDKN2B-AS1 | RET | CIC | TCF12 | G7015 | G7157 | ROS1 | PDGFRA | STK11 | KIT | G673 | APC | RB1 | PHLDB1 | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | KLRK1 | G472 | JAK3 | NF1 | EMP3 | G672 | CRBN | MGMT | IDH2 | MLH3 | RTEL1 | TOP2A | ABL1 | MPL | MLH1 | G1029 | PDGFRB | G238 | RASSF1 | G5728 | CSF1R | CLCN3 | MSH2 | CADM1 | MIR196A2 | NRAS | G1956 | EPB41L3 | PIK3CA | BRCA2 | FGFR3 | HOTAIR | G7124 | ZMIZ1 | G2099 | RASSF2 | RTEL1-TNFRSF6B | G4233 | THBS1 | G4851 | IDH1 | BCR | CCDC26 | FUBP1

疾病靶点研报
Oligodendroglioma

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