Congenital Hereditary Endothelial Dystrophy Type II

About the Disease
Corneal Endothelial Dystrophy, also known as congenital hereditary endothelial dystrophy of cornea, is related to corneal dystrophy and perceptive deafness and corneal dystrophy, endothelial, x-linked. An important gene associated with Corneal Endothelial Dystrophy is SLC4A11 (Solute Carrier Family 4 Member 11). The drugs Prednisolone phosphate and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include endothelial, eye and neutrophil, and related phenotypes are corneal opacity and corneal stromal edema

Common Targets
SLC4A11

Note: If you'd like to get a target analysis report for Congenital Hereditary Endothelial Dystrophy Type II, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Congenital Hereditary Endothelial Dystrophy Type II at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Osteopetrosis | Cole-Carpenter Syndrome | Pontocerebellar Hypoplasia Type 2 | Bipolar Disorder | L-2-Hydroxyglutaric Aciduria | Pyruvate Decarboxylase Deficiency | Crohn's Disease | Split Hand-foot Malformation | Heroin Dependence | Renal Hypouricemia | Hypermetropia | Alpha-mannosidosis | Vitamin B12 Deficiency | Spondylolisthesis | Pernicious Anemia | Dermatitis | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Miyoshi Myopathy | Vertebrobasilar Insufficiency | Stroke | Blepharo-cheilo-odontic Syndrome | Familial Cerebral Amyloid Angiopathy | Chronic Idiopathic Myelofibrosis | Meningococcal Infections | Hemolytic Uremic Syndrome, Atypical | Huntington's Disease-like 2 | Rhabdoid Tumor | Charcot-Marie-Tooth Disease Type 3 | Spinocerebellar Ataxia Type 42 | Delayed Sleep Phase Syndrome | Neurofibromatosis Type 2 | Epidermal Nevus Syndrome | Congenital Heart Defects | Sweet Syndrome | Retinal Vasculitis | Thyroid Dysgenesis | Hepatoblastoma | 3-methylglutaconic Aciduria | Hartnup Disease | Hypoalbuminemia | Thrombasthenia | Fatty Aldehyde Dehydrogenase Deficiency | Cryopyrin-associated Periodic Syndromes | Wolfram Syndrome | Scleritis | Cystinuria | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Parvovirus B19 Infection | Myasthenia Gravis | Spermatocele | Macrophagic Myofasciitis | Pulmonary Vein Stenosis | Bietti Crystalline Dystrophy | Schnyder Crystalline Corneal Dystrophy | Borjeson-Forssman-Lehmann Syndrome | Myopathy | Distal Myopathy | Kashin-Beck Disease | Bartter Syndrome | Neurofibromatosis | Amyloidosis | Epidermolysis Bullosa Simplex, Localized | Hyperkeratosis | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Glaucoma | Glomerulonephritis, Membranous | Mitochondrial Encephalomyopathy | Macular Corneal Dystrophy Type 1 | Dermatofibrosarcoma | Angiomyolipoma | Seizures-scoliosis-macrocephaly Syndrome | Spondylometaphyseal Dysplasia | Nephropathy | Rhabdomyosarcoma | Cryptosporidiosis | Genee-Wiedemann Syndrome | Occipital Neuralgia | Pierre Robin Syndrome | Pierpont Syndrome | Diamond-Blackfan Anemia | Primary Erythromelalgia | Enlarged Vestibular Aqueduct | Dent Disease | Shock, Cardiogenic | Chronic Neutrophilic Leukemia | Senior-Loken Syndrome | Polydactyly | Peutz-Jeghers Syndrome | Cyclic Vomiting Syndrome | C3 Glomerulonephritis | Familial Advanced Sleep Phase Syndrome | Cornelia De Lange Syndrome | Bacterial Meningitis | Early Infantile Epileptic Encephalopathy 13 | Shwachman-Bodian-Diamond Syndrome | Sleep Apnea, Central | Ectodermal Dysplasia | Encephalitis | Intracranial Hypertension | Plasma Cell Dyscrasia | Stroke, Hemorrhagic | Pyoderma Gangrenosum | Glycogen Storage Disease Type 0, Muscle | Peyronie's Disease | Syndactyly | Niemann-Pick Disease, Type A | Cabezas Syndrome | Scoliosis | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Leigh Syndrome | Spinocerebellar Ataxia Type 7 | Tularemia | Keratosis, Actinic | Varices | Multiple Sclerosis, Primary Progressive | Pemphigoid | Myositis, Focal | Isovaleric Acidemia | Plasma Cell Leukemia | Dystonia-parkinsonism, X-linked | Progressive Familial Intrahepatic Cholestasis | Wieacker-Wolff Syndrome | Polycythemia | Autism | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Neurocutaneous Melanocytosis | Giant Cell Arteritis | Hepatitis A | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Metabolic Syndrome | Rothmund-Thomson Syndrome | Retinitis Pigmentosa 3 | Glycogen Storage Disease Type 3 | Alopecia Totalis | Beta-Propeller Protein-associated Neurodegeneration | McCune-Albright Syndrome | Frontotemporal Dementia | Hypersensitivity | Pierson Syndrome | Melanocytic Nevus | Ameloblastoma | Erectile Dysfunction | Charcot-Marie-Tooth Disease Axonal Type 2N | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Spinocerebellar Ataxia Type 17 | Botulism | Fanconi Syndrome | Pulmonary Alveolar Microlithiasis | Sclerosteosis 2 | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Aldosterone Deficiency | Alagille Syndrome | Spinal Muscular Atrophy Type 2 | Nijmegen Breakage Syndrome | Orotic Aciduria | Ichthyosis | Mabry Syndrome | Atelosteogenesis Type 2 | Primary Sclerosing Cholangitis | Charcot-Marie-Tooth Disease Type 2E | GM2-gangliosidosis AB Variant | Smith-Magenis Syndrome | Spitz Nevus | Thyrotoxic Periodic Paralysis | Mumps | Sezary Syndrome | Anorectal Malformations | PASLI Disease | Lattice Corneal Dystrophy Type 1 | N-acetylglutamate Synthase Deficiency | CEDNIK Syndrome | Loeys-Dietz Syndrome Type 4 | Hypotension, Orthostatic | Renpenning Syndrome | Motor Neuron Diseases | Chronic Mucocutaneous Candidiasis | Cutaneous Angiosarcoma | Anal Fissure | Birt-Hogg-Dube Syndrome | T-cell Chronic Lymphocytic Leukemia | Familial Hemiplegic Migraine | Combined Pituitary Hormone Deficiency | Craniometaphyseal Dysplasia | Progressive Myoclonic Epilepsy | Ollier Disease | Cold-induced Sweating Syndrome | Guttate Psoriasis | Chondrosarcoma | Salla Disease | Prune Belly Syndrome | Autoimmune Polyendocrinopathy Syndrome Type I | Hypertension, Renal | Leishmaniasis, Visceral | Eosinophilia | Patent Ductus Arteriosus | Erysipelas | Retinal Dystrophy | Amelogenesis Imperfecta | Hereditary Spastic Paraplegia | GAPO Syndrome | Celiac Disease | Migraine | Corneal Ulcer | Glaucomatocyclitic Crisis | Diffuse Intrinsic Pontine Glioma | T-cell Prolymphocytic Leukemia | Charcot-Marie-Tooth Disease Type 4 | Vulvovaginitis | Sialidosis | Vitamin D Deficiency | Progressive Familial Intrahepatic Cholestasis Type 3 | Behavioral Variant Of Frontotemporal Dementia | Dystonia Musculorum Deformans | Clouston Hidrotic Ectodermal Dysplasia | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Tatton-Brown-Rahman Syndrome | Greig Cephalopolysyndactyly Syndrome | Meningioma | Hepatopulmonary Syndrome | Low Phospholipid Associated Cholelithiasis | Hyper IgE Syndrome | Sertoli Cell-only Syndrome | Exfoliative Dermatitis | Exotropia | Neutrophilia | Cutaneous Lupus Erythematosus | Geleophysic Dysplasia | Cranial Nerve Disease | Lymphoproliferative Disorders | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Bruck Syndrome | Primary Cutaneous Amyloidosis | Autoimmune Disease | Hemophagocytic Lymphohistiocytosis | Poikiloderma With Neutropenia | Pituitary Stalk Interruption Syndrome | Preaxial Polydactyly | Cluster Headache | Heterotopic Ossification | Craniosynostosis | Rhabdomyosarcoma, Alveolar | Myocardial Infarction | Antisynthetase Syndrome | Amelanotic Melanoma | Hyperparathyroidism, Secondary | Congenital Aniridia | Prurigo Nodularis | Zimmermann-Laband Syndrome | Hepatitis B, Chronic | T-cell Lymphoma, Subcutaneous Panniculitis-like | Keratosis | Connective Tissue Disorders | Uveitis, Anterior | Angioedema, Acquired | Roberts Syndrome | Hereditary Multiple Exostoses | Colorectal Adenoma | Encephalocele | Adrenal Insufficiency | Pulmonary Stenosis | Hyperuricemia | Speech Disorders | Heart Failure | Currarino Syndrome | Reflex Epilepsy | Osteochondroma | Hepatic Veno-occlusive Disease | Kallmann Syndrome | Rhabdomyosarcoma, Embryonal | Chronic Granulomatous Disease | Chronic Periodontitis | Swine Influenza | Aneurysm, Abdominal Aortic | Congenital Hemolytic Anemia | Schwartz-Jampel-Aberfeld Syndrome | Nasodigitoacoustic Syndrome | Primary Pigmented Nodular Adrenocortical Disease | Noonan Syndrome | Proopiomelanocortin Deficiency | Allergic Contact Dermatitis | Pyelonephritis | Cholestasis, Intrahepatic | Venous Insufficiency | Patent Foramen Ovale | Crimean-Congo Hemorrhagic Fever | Blue Nevus | Myelomeningocele | Hypolipoproteinemia | Bicuspid Aortic Valve | Erythema Nodosum | Zygomycosis | Phosphoglycerate Dehydrogenase Deficiency | Fontaine Progeroid Syndrome | Farber Disease | Gout | Epidermolysis Bullosa Dystrophica | Inborn Errors Of Metabolism | Tietze Syndrome | Anovulation | Carney-Stratakis Syndrome | Synovitis | Cellulitis | Enhanced S-cone Syndrome | Cutis Laxa | Reticular Dysgenesis | TARP Syndrome | Splenomegaly | Anterior Segment Dysgenesis | Charcot-Marie-Tooth Disease Type 4D | Hamartoma | Hypertensive Nephropathy | Gastric Atrophy | Palsy, Cerebral | Cerebral Cavernous Malformations | Polyarteritis Nodosa | Renal Oncocytoma | Behcet's Disease | Rubeosis Iridis | Carbohydrate Metabolism Disorders | Retinopathy, Diabetic | Pulmonary Alveolar Proteinosis | Asthma | Megalencephaly | Compartment Syndrome | Cushing Syndrome | Myoclonic Atonic Epilepsy | Follicular Dendritic Cell Sarcoma | Hypertension, Essential | Autonomic Neuropathy | Spina Bifida | Spinocerebellar Ataxia Type 1 | Panuveitis | Peritonitis | Opisthorchiasis | Constipation | Pseudoachondroplasia | Sleep Disorder | Mevalonate Kinase Deficiency | Agoraphobia | Mitochondrial DNA Depletion Syndrome 13 | Norrie Disease | Lymphomatoid Granulomatosis | Esophageal Carcinoma | Contact Dermatitis | Leukoencephalopathy, Progressive Multifocal | Paracoccidioidomycosis | Porphyria, Acute Intermittent | Sick Sinus Syndrome | Phenylketonuria | Paraganglioma, Carotid Body | Perry Syndrome | Smoldering Myeloma | Holoprosencephaly | Hypervalinemia | Pelvic Inflammatory Disease | Hydrocephalus, Normal Pressure | Nephrotic Syndrome Type 1 | Tonsillitis | Intestinal Hypomagnesemia 1 | Spinocerebellar Ataxia Type 6 | Rolandic Epilepsy | Familial Digital Arthropathy-brachydactyly | ACTH-independent Macronodular Adrenal Hyperplasia | Rheumatic Heart Disease | Acromesomelic Dysplasia | Dyskeratosis Congenita | Pathological Gambling | Renal Tubular Acidosis | Cardiospondylocarpofacial Syndrome | Epidermolytic Hyperkeratosis | Thanatophoric Dysplasia | Autosomal Recessive Bestrophinopathy | Down Syndrome | Ureteropelvic Junction Obstruction | Carcinoma, Signet Ring Cell | Xeroderma Pigmentosum Variant Type | Hypertrophy | Best Macular Dystrophy | Mast Cell Leukemia | Porphyria, Variegate | Amblyopia | Isobutyryl-CoA Dehydrogenase Deficiency | Lactose Intolerance | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Hodgkin Lymphoma | Joubert Syndrome 2 | Sclerosing Cholangitis | Common Cold | Heart Block | GLUT1 Deficiency Syndrome | Vogt-Koyanagi-Harada Syndrome | Neuromyelitis Optica | Fanconi Anemia | Orthostatic Intolerance | Palmoplantar Keratoderma | Micro Syndrome | Chromosome 9q34.3 Deletion Syndrome | Fibromyalgia | B-cell Prolymphocytic Leukemia