Chordoma

About the Disease
Chordoma, also known as chdm, is related to chondroid chordoma and chondrosarcoma. An important gene associated with Chordoma is CHDM (Chordoma), and among its related pathways/superpathways are COPI-independent Golgi-to-ER retrograde traffic and Cytoskeletal Signaling. The drugs Dasatinib and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include bone, spinal cord and brain, and related phenotypes are astrocytoma and chordoma

Common Targets
CDK4 | WNT8A | PIK3CA | G5243 | BCR | G1956 | FLT4 | MYO10 | CDK9 | KDR | GART | G2064 | ZFHX4 | MUC1 | UROD | TUBB6 | BLM | DDX53 | NIPBL | CCND3 | RAB32 | PDGFRA | TMEM63C | PSKH2 | ITLN1 | ERBB4 | Histone deacetylase (nonspecified subtype) | TYMS | ZFP57 | KDM6B | LAMA1 | SLC16A5 | CTNNB1 | KIT | TOP2A | PALB2 | FAM181B | G2146 | CDK6/Cyclin D3 | SMARCB1 | DHFR | G238 | ABL1 | G5133 | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | MIR29B1 | TGFB3 | MIR29B2 | RNF123 | G5728 | TBXT | COL11A2 | HECW2 | G1029 | CSF1R | ERCC5 | NRAS | KDM6A | CDK4/Cyclin D3 | PDGFRB | TCERG1L | CDK6 | FGR | NPR3 | PON3 | BRCA2 | FAM110B

Note: If you'd like to get a target analysis report for Chordoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Chordoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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