Pseudoexfoliation Syndrome

About the Disease
Exfoliation Syndrome, also known as pseudoexfoliation glaucoma, is related to open-angle glaucoma and cataract, and has symptoms including progressive decreased vision An important gene associated with Exfoliation Syndrome is LOXL1 (Lysyl Oxidase Like 1), and among its related pathways/superpathways are Extracellular matrix organization and Burn wound healing. The drugs Latanoprost and Timolol have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and retina, and related phenotypes are cataract and lens subluxation

Common Targets
PIGX | SIL1 | ISLR | MIR1268A | CTNNA1 | MIR1304 | HEXA-AS1 | MTHFR | TLN2 | FAM120B | FLT1 | CDKN2B-AS1 | CCN2 | F2 | RBFOX2 | MYOC | PCDH7 | MIR3161 | CLU | DICER1 | B4GALNT4 | LOC105369455 | AGPAT1 | LOXL1-AS1 | LOXL1 | LINC00484 | HEXA | F5 | CEP152 | CYP39A1 | PEAK1 | CEP19 | NOVA1-DT | PON1 | FBLN5 | CACNA1A | LOC105376400 | HSPA1A | CNTNAP2 | SNX20 | TLL1 | Uncharacterized LOC101929670, transcript variant X1 | FANCA | TLCD5 | HSPA1B | AHI1-DT | RBMS3 | LOC105376558 | LOC105376566 | BMP5 | TBC1D21 | FNDC3B | LOC105372561 | G6647 | LOC105372639 | ACCSL | SARDH | VGLL3 | AHI1 | LOC105379341

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