Pseudohypoparathyroidism Type 1B

About the Disease
Pseudohypoparathyroidism, Type Ib, also known as pseudohypoparathyroidism type 1b, is related to hyperphosphatemia and pseudohypoparathyroidism. An important gene associated with Pseudohypoparathyroidism, Type Ib is GNAS (GNAS Complex Locus), and among its related pathways/superpathways are Presynaptic function of Kainate receptors and Endochondral ossification. The drugs Benzocaine and Theophylline have been mentioned in the context of this disorder. Affiliated tissues include thyroid, kidney and bone, and related phenotypes are pseudohypoparathyroidism and hyperphosphatemia

Common Targets
SNU13 | PPIEL | GET1 | GNAS-AS1 | GNAS | STX16

Note: If you'd like to get a target analysis report for Pseudohypoparathyroidism Type 1B, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Pseudohypoparathyroidism Type 1B at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Sepiapterin Reductase Deficiency | Yellow Fever | Lentigo | Lymphoma, Follicular | Heterotopic Ossification | Tumoral Calcinosis | Persistent Hyperplastic Primary Vitreous | Optic Neuropathy | Choriocarcinoma | Saul-Wilson Syndrome | Bacterial Meningitis | Irritable Bowel Syndrome | Genee-Wiedemann Syndrome | Cirrhosis | Agammaglobulinemia | Anuria | Aphasia | Abetalipoproteinemia | Neuroleptic Malignant Syndrome | Stroke, Ischemic | VACTERL Association | Pulmonary Stenosis | Micro Syndrome | Retinitis Pigmentosa | Esophageal Adenocarcinoma | Paracoccidioidomycosis | Brachial Plexus Neuropathy | Scoliosis | Lymphoma, Mantle Cell | Atrial Septal Defect | Nutrition Disorders | CREST Syndrome | Thrombasthenia | Gardner Syndrome | Follicular Dendritic Cell Sarcoma | Holt-Oram Syndrome | Tuberculous Meningitis | Pulmonary Alveolar Microlithiasis | Pancytopenia | Thymoma, Malignant | Multiple System Atrophy | Porphyria, Acute Intermittent | Tetanus | Nicolaides-Baraitser Syndrome | Dysgerminoma | Osteoporosis | Blepharophimosis Syndrome | Spinocerebellar Ataxia Type 6 | Autoimmune Disease | Primary Familial Brain Calcification | Paget's Disease Of The Breast | Hamartoma | Hepatitis D | Acrodermatitis | Swine Influenza | Lipid Storage Diseases | Kohlschutter-Tonz Syndrome | Cardiomyopathy, Restrictive | Hoyeraal-Hreidarsson Syndrome | Renal Dysplasia | Endophthalmitis | Congenital Myasthenic Syndrome | Panic Disorder | Turner's Syndrome | Waldenstrom Macroglobulinemia | Nephropathy | Migraine | Congenital Hereditary Endothelial Dystrophy Type I | Schwannoma | Acute Generalized Exanthematous Pustulosis | Fibrillation, Atrial | Amelogenesis Imperfecta | H Syndrome | Waardenburg Syndrome Type 4A | Primary Hyperoxaluria Type 3 | Macrophagic Myofasciitis | Meconium Ileus | Emery-Dreifuss Muscular Dystrophy | Cutis Laxa | Neuromuscular Disorders | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Neurofibroma | 3-methylglutaconic Aciduria | Acquired Partial Lipodystrophy | Anterior Segment Dysgenesis | Porokeratosis | Congenital Afibrinogenemia | Iron Metabolism Disorders | Maple Syrup Urine Disease | Uterine Leiomyoma | Angiomyolipoma | Rhabdomyosarcoma, Embryonal | Diffuse Intrinsic Pontine Glioma | Phenylketonuria | Duchenne Muscular Dystrophy | Primary Cutaneous Amyloidosis | Persistent Truncus Arteriosus | Paraplegia | Leigh Syndrome | Martsolf Syndrome | TARP Syndrome | Trimethylaminuria | Relapsing Polychondritis | Atelosteogenesis Type 1 | Hypertension | Kaposiform Hemangioendothelioma | Tic Disorder | Cleidocranial Dysplasia | Pierpont Syndrome | Epidermolytic Hyperkeratosis | Marinesco-Sjogren Syndrome | Otitis Externa | Absence Epilepsy | Adenoma, Pleomorphic | Osteogenesis Imperfecta Type III | Scleroderma, Diffuse | Paroxysmal Nocturnal Hemoglobinuria | B-cell Prolymphocytic Leukemia | Keratoacanthoma | Pulverulent Zonular Cataract | Transient Bullous Dermolysis Of The Newborn | Spinocerebellar Ataxia Type 1 | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Lymphangioleiomyomatosis | Borjeson-Forssman-Lehmann Syndrome | Marshall-Smith Syndrome | Ganglioneuroma | Lymphangiomatosis | Charcot-Marie-Tooth Disease, Type 1A | Amish Infantile Epilepsy Syndrome | Amyloidosis | Walker-Warburg Syndrome | Pemphigoid | Cardiac Sarcoidosis | Patent Foramen Ovale | Spinocerebellar Ataxia Type 40 | Lymphedema-distichiasis Syndrome | Cranial Nerve Disease | Anovulation | Stargardt Disease | Chronic Myeloid Leukemia | Periventricular Leukomalacia | Hyperthermia, Malignant | Preaxial Polydactyly | Chronic Lymphocytic Leukemia | Gitelman Syndrome | Ocular Hypertension | Renal Hypomagnesemia 3 | McKusick Type Metaphyseal Chondrodysplasia | Portal Vein Thrombosis | Allan-Herndon-Dudley Syndrome | Lamellar Ichthyosis | Glycogen Storage Disease Type 1a | Pseudohypoparathyroidism Type 1C | Waardenburg Syndrome | Pneumothorax | Chronic Neutrophilic Leukemia | Von Hippel-Lindau Disease | Common Cold | Bartsocas-Papas Syndrome | Restrictive Dermopathy | Hyperbilirubinemia, Neonatal | Microcephaly | Cranioectodermal Dysplasia | Crohn's Disease | Asthma, Exercise-induced | Retinal Coloboma | Mabry Syndrome | Glaucoma | Dupuytren Disease | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Apraxia | Gigantism | Glomerulonephritis, Membranous | Epidermolysis Bullosa Acquisita | Polymyositis | Granuloma Annulare | Poretti-Boltshauser Syndrome | Primary Carnitine Deficiency | Multiple Sclerosis, Primary Progressive | Mood Disorder | Congenital Poikiloderma | Trichothiodystrophy | Uremia | McCune-Albright Syndrome | Liver Diseases | Dowling-Degos Disease | Familial Exudative Vitreoretinopathy | Microtia | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Chromosome 8q21.11 Deletion Syndrome | Blau Syndrome | Charcot-Marie-Tooth Disease, Type 6 | Epidermolysis Bullosa Simplex, Generalized | Scleritis | Cholangitis | Lipoma | Bronchitis | Congenital Hemolytic Anemia | Larsen Syndrome | Cerebellar Ataxia, Cayman Type | Creutzfeldt-Jakob Disease | CHARGE Syndrome | Waardenburg Syndrome Type 1 | Early Infantile Epileptic Encephalopathy 13 | Myopathy | Hepatitis | Pernicious Anemia | Myelitis | Cholangiocarcinoma | Glioblastoma | Trachoma | Influenza | Pupil Disorders | Corneal Ulcer | Alpha-mannosidosis | Spondylometaphyseal Dysplasia | Autosomal Recessive Spastic Paraplegia Type 54 | Renal Medullary Carcinoma | Melnick-Needles Syndrome | Oculocutaneous Albinism | Ependymoma | Feingold Syndrome | Leiomyosarcoma | Rhabdoid Tumor | Takotsubo Cardiomyopathy | Seasonal Mood Disorder | Auriculocondylar Syndrome | Intracranial Hypertension | Borderline Personality Disorder | Loeys-Dietz Syndrome | Oculopharyngeal Muscular Dystrophy | Disseminated Superficial Actinic Porokeratosis | Cerebral Cavernous Malformations | Multicystic Renal Dysplasia | Pyoderma Gangrenosum | Osteoarthritis | Sialidosis | Angiosarcoma | Lassa Fever | Achromatopsia | Infantile Neuroaxonal Dystrophy | Patent Ductus Arteriosus | Mosaic Variegated Aneuploidy Syndrome 2 | Microphthalmia, Syndromic 7 | Van Der Knaap Disease | Obesity, Morbid | Glutaric Aciduria Type 3 | Lymphoproliferative Disease, X-linked | Tylosis With Esophageal Cancer | Stuve-Wiedemann Syndrome | Familial Digital Arthropathy-brachydactyly | Sponastrime Dysplasia | Progressive Familial Intrahepatic Cholestasis | Spinocerebellar Ataxia Type 16 | Sleep Apnea | IgA Nephropathy | Jaundice, Obstructive | Primary Progressive Aphasia | Lymphoma, AIDS-related | Wieacker-Wolff Syndrome | Platelet Disorders | Left Ventricular Noncompaction | Epithelioid Hemangioma | Hereditary Folate Malabsorption | Takenouchi-Kosaki Syndrome | Axenfeld-Rieger Syndrome | Angioedema, Acquired | Epidermolysis Bullosa Dystrophica | Myelodysplasia | Parvovirus B19 Infection | Oculocutaneous Albinism Type 2 | Nemaline Myopathy | Malignant Fibrous Histiocytoma | Lymphoproliferative Disorders | Guttate Psoriasis | Rhizomelic Chondrodysplasia Punctata | Congenital Heart Block | Hyperekplexia | Hypothalamic Obesity | Multisystemic Smooth Muscle Dysfunction Syndrome | Pyruvate Kinase Deficiency | Brenner Tumor | Spitzoid Melanoma | Sarcoma | Branchiootorenal Syndrome | Glutathione Synthetase Deficiency | Silver-Russell Syndrome | Ichthyosis Hystrix, Curth-Macklin Type | Bipolar Disorder | Focal Facial Dermal Dysplasia | Spermatocele | Menkes Disease | Polyarteritis Nodosa | GLUT1 Deficiency Syndrome | Subcortical Band Heterotopia | Hereditary Hemorrhagic Telangiectasia | Ameloblastoma | Blue Nevus | Anal Fissure | Papillorenal Syndrome | Spasticity | Pemphigus Foliaceus | Malnutrition | Congenital Muscular Dystrophy | Incontinentia Pigmenti | Speech Disorders | Fetal Alcohol Syndrome | Cryptococcal Meningitis | Choroideremia | Hepatitis B, Chronic | Oligodendroglioma | Meningococcal Meningitis | Traboulsi Syndrome | Cerebral Amyloid Angiopathy | X-linked Creatine Transporter Deficiency | Encephalocele | CEDNIK Syndrome | Hypoparathyroidism | Growth Hormone Excess | Sarcomatoid Carcinoma Of The Lung | Reflex Epilepsy | Barrett Esophagus | Renpenning Syndrome | Mucormycosis | Imerslund-Grasbeck Syndrome | Inflammatory Joint Disease | Oculocutaneous Albinism Type 1 | Pulmonary Alveolar Proteinosis | Paronychia | Spondylolisthesis | Charcot-Marie-Tooth Disease, Type 2C | Short-chain Acyl-CoA Dehydrogenase Deficiency | Tangier Disease | Myosin Storage Myopathy | Pantothenate Kinase-associated Neurodegeneration | Osteomalacia | Alagille Syndrome | Adenomyosis | Aldosterone Deficiency | Exfoliative Dermatitis | Varices | Hypertensive Retinopathy | Retinal Telangiectasia | Pierre Robin Syndrome | Sotos Syndrome | Cystitis, Interstitial | Persistent Mullerian Duct Syndrome | Familial Male-limited Precocious Puberty | Multiple Myeloma | Multiple Epiphyseal Dysplasia | Periodic Limb Movement Disorder | Alzheimer Disease, Late Onset | Palsy, Cerebral | Chronic Enteropathy Associated With SLCO2A1 Gene | Torticollis | Craniofrontonasal Syndrome | 3-methylglutaconic Aciduria Type IV | Greenberg Dysplasia | Learning Disability | Superficial Spreading Melanoma | Schuurs-Hoeijmakers Syndrome | Dystonia-parkinsonism, X-linked | Usher Syndrome Type I | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Motion Sickness | Hypopigmentation | Polyneuropathy | Heart Block | Poikiloderma With Neutropenia | Neuroectodermal Tumors, Primitive | Crisponi Syndrome | Mycosis Fungoides | Supravalvular Aortic Stenosis | Craniometaphyseal Dysplasia | Kallmann Syndrome | Parkinson's Disease | IgA Deficiency | Central Pain Syndrome | Cardiomyopathy, Dilated, 1L | Primary Lateral Sclerosis | Spinocerebellar Ataxia Type 8 | Juvenile Polyposis | Acute Motor Axonal Neuropathy | Esophageal Carcinoma | Hypervalinemia | Cancer, Bladder | Generalized Epilepsy And Paroxysmal Dyskinesia | Schizophrenia | Conduct Disorder | Hidradenitis Suppurativa | Vascular Calcification | Pseudohypoparathyroidism Type 2 | Dengue Hemorrhagic Fever | Pitt-Hopkins Syndrome | Rift Valley Fever | Noonan Syndrome | Endometrial Hyperplasia | Hypercholesterolemia | Cardiomyopathy, Hypertrophic