Retinal Degeneration

About the Disease
Peripheral Retinal Degeneration, also known as peripheral degeneration of retina, is related to late-onset retinal degeneration and ceroid lipofuscinosis, neuronal, 3. An important gene associated with Peripheral Retinal Degeneration is CLN3 (CLN3 Lysosomal/Endosomal Transmembrane Protein, Battenin), and among its related pathways/superpathways are Visual phototransduction and Retinoid cycle disease events. The drugs Dorzolamide and Carbonic Anhydrase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and bone marrow, and related phenotypes are no effect and no effect

Common Targets
SLC12A2 | NEO1 | CFB | MYD88 | FAM162B | FAM161A | GUCY2D | VOR Complex | G7852 | CFD | PRPH2 | ABHD12 | PDE6A | beta-Secretase (nonspecified subtype) | PLA2G5 | CLN3 | SORT1 | LRP5 | RAX2 | RHO | RPGRIP1 | CRX | LCA5 | CERKL | HTRA1 | FAT3 | PRPF8 | TOPORS | IMPDH1 | AKAP2 | DRAM2 | GADD45A | IFT88 | CEP290 | RD3 | GSK3B | MVK | TULP1 | PDE6B | MID1 | RLBP1 | ABCA4 | LRIT3 | TSPO | JAG1 | NRL | MERTK | BACE1 | EYS | RB1 | RP1 | ARMS2 | HK1 | CD59 | PALM2AKAP2 | PITPNM3 | PDZD7 | PROM1 | RP2 | CR1 | USH2A | RDH12 | LOC105378525 | CDHR1 | ERN1 | VCP | C1QTNF5 | NOX3 | G7422 | BEST1 | ATP6 | IFT43 | CNGB1 | MSI2 | Complement Complex | OPN1SW | PCARE | CCR5 | ZNF692 | IL1B | CRB1 | CEP164 | COL11A1 | NADPH Oxidase Complex | ATF6 | MFRP | COL2A1 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | USH1C | GRN | RPE65 | ARFGAP2 | NADPH Oxidase (nonspecified subtype) | NTRK2 | RP1L1 | CACNA1F | SLC6A6 | NR2E3 | PRPS1 | ASRGL1 | FGFR2 | Protein farnesyltransferase

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