Disease

Retinal Degeneration

About the Disease
Peripheral Retinal Degeneration, also known as peripheral degeneration of retina, is related to late-onset retinal degeneration and ceroid lipofuscinosis, neuronal, 3. An important gene associated with Peripheral Retinal Degeneration is CLN3 (CLN3 Lysosomal/Endosomal Transmembrane Protein, Battenin), and among its related pathways/superpathways are Visual phototransduction and Retinoid cycle disease events. The drugs Dorzolamide and Carbonic Anhydrase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and bone marrow, and related phenotypes are no effect and no effect

Common Targets
SLC12A2 | NEO1 | CFB | MYD88 | FAM162B | FAM161A | GUCY2D | VOR Complex | G7852 | CFD | PRPH2 | ABHD12 | PDE6A | beta-Secretase (nonspecified subtype) | PLA2G5 | CLN3 | SORT1 | LRP5 | RAX2 | RHO | RPGRIP1 | CRX | LCA5 | CERKL | HTRA1 | FAT3 | PRPF8 | TOPORS | IMPDH1 | AKAP2 | DRAM2 | GADD45A | IFT88 | CEP290 | RD3 | GSK3B | MVK | TULP1 | PDE6B | MID1 | RLBP1 | ABCA4 | LRIT3 | TSPO | JAG1 | NRL | MERTK | BACE1 | EYS | RB1 | RP1 | ARMS2 | HK1 | CD59 | PALM2AKAP2 | PITPNM3 | PDZD7 | PROM1 | RP2 | CR1 | USH2A | RDH12 | LOC105378525 | CDHR1 | ERN1 | VCP | C1QTNF5 | NOX3 | G7422 | BEST1 | ATP6 | IFT43 | CNGB1 | MSI2 | Complement Complex | OPN1SW | PCARE | CCR5 | ZNF692 | IL1B | CRB1 | CEP164 | COL11A1 | NADPH Oxidase Complex | ATF6 | MFRP | COL2A1 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | USH1C | GRN | RPE65 | ARFGAP2 | NADPH Oxidase (nonspecified subtype) | NTRK2 | RP1L1 | CACNA1F | SLC6A6 | NR2E3 | PRPS1 | ASRGL1 | FGFR2 | Protein farnesyltransferase

疾病靶点研报
Retinal Degeneration

Note: If you'd like to get a target analysis report for Retinal Degeneration, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Retinal Degeneration at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Hypothyroidism | Achromatopsia | T-cell Prolymphocytic Leukemia | Low Phospholipid Associated Cholelithiasis | Crigler-Najjar Syndrome | Hemosiderosis | Roberts Syndrome | Encephalocele | Esophageal Carcinoma | Gerodermia Osteodysplastica | Thrombophlebitis | Tinea Versicolor | Amyotrophic Lateral Sclerosis, Juvenile | Congenital Heart Defects | Myosin Storage Myopathy | Androgen Insensitivity | Atrioventricular Septal Defect | Chloridorrhea, Congenital | Spinal And Bulbar Muscular Atrophy | Orthostatic Intolerance | Hereditary Sensory Neuropathy Type 1 | Leukodystrophies | Delayed Sleep Phase Syndrome | Leukoplakia, Oral | Chronic Leukemia | Trichorhinophalangeal Syndrome | Myasthenia | Multiple Sulfatase Deficiency | Cholestasis | Stromal Corneal Dystrophy | Wagner Disease | Infertility, Male | Waardenburg Syndrome | Lymphomatoid Granulomatosis | Lymphoma, Mantle Cell | Fetal Alcohol Syndrome | Malonyl-CoA Decarboxylase Deficiency | Hyperlipidemia | Peeling Skin Syndrome Type B | Atopic Dermatitis | Persistent Truncus Arteriosus | Coronary Artery Disease | Dowling-Degos Disease | Constipation | Enterocolitis, Necrotizing | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Liddle Syndrome | Nicolaides-Baraitser Syndrome | Pontocerebellar Hypoplasia | Situs Inversus | Axenfeld-Rieger Syndrome | Hypermethioninemia | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Narcolepsy | Anthrax | Congenital Fiber-type Disproportion Myopathy | Familial Episodic Pain Syndrome | Gangliosidosis | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Cerebral Amyloid Angiopathy | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Gynecomastia | Hypopigmentation | Microcephalic Primordial Dwarfism | Multiple System Atrophy | Chordoma | Schizophrenia | Budd-Chiari Syndrome | Cranioectodermal Dysplasia | Johanson-Blizzard Syndrome | Primary Lateral Sclerosis | Waardenburg Syndrome Type 1 | Hyperacusis | Polycythemia Vera | Lymphoma | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Pitt-Hopkins Syndrome | Dupuytren Disease | Recurrent Respiratory Papillomatosis | Tonsillitis | Charcot-Marie-Tooth Disease, Type 1A | Pulmonary Alveolar Microlithiasis | Cervical Dystonia | Oligospermia | Granular Corneal Dystrophy | Colitis | Hypophosphatasia | Nephrotic Syndrome | Gastroenteritis | Nasodigitoacoustic Syndrome | Leukemia | Ganglioneuroma | Spinal Muscular Atrophy | Lipid Storage Diseases | MELAS Syndrome | Rickets | Holoprosencephaly | Liebenberg Syndrome | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Diffuse Palmoplantar Keratoderma | Mountain Sickness | Specific Granule Deficiency | GM2-gangliosidosis AB Variant | Chronic Lymphocytic Leukemia | Schwartz-Jampel-Aberfeld Syndrome | Hashimoto Thyroiditis | Sweet Syndrome | Chorioretinitis | Juvenile Myelomonocytic Leukemia | Keratosis | Cole-Carpenter Syndrome | Ventricular Septal Defect | Parkinson's Disease | Sclerocornea | Hidradenitis | Nemaline Myopathy 8 | Hypersomnia | Liver Failure | Anal Fissure | Werner's Syndrome | Pseudohermaphroditism | Hypertension | Sclerosing Cholangitis | Asphyxia Neonatorum | Erectile Dysfunction | Hypogonadism | Amish Infantile Epilepsy Syndrome | Pseudohypoparathyroidism Type 1C | Cerebellar Ataxia, Cayman Type | Hyperuricemia | Cancer, Breast | Wolfram Syndrome 2 | Spinocerebellar Ataxia Type 31 | Ocular Surface Squamous Neoplasia | Aromatic L-amino Acid Decarboxylase Deficiency | Varicocele | Platelet Disorders | Alcoholism | Sarcoidosis, Pulmonary | Urticaria | Tetanus | Glomerulonephritis | Thrombosis | Progressive Myoclonic Epilepsy | Hereditary Spastic Paraplegia | Cantu Syndrome | Kleine-Levin Syndrome | Mitochondrial Encephalomyopathy | Lysosomal Acid Lipase Deficiency | Nephroblastoma | Bursitis | Urofacial Syndrome | IgA Nephropathy | Tuberculous Meningitis | Heterotaxy | D-2-Hydroxyglutaric Aciduria | Knobloch Syndrome | Encephalopathy, Hepatic | Dent Disease | Motion Sickness | Follicular Dendritic Cell Sarcoma | Common Variable Immunodeficiency | Hartsfield Syndrome | Hemoglobinopathies | Infantile Refsum Disease | Anuria | Schistosomiasis Mansoni | Goiter, Nodular | Angiomyolipoma | Impetigo | Chondrosarcoma | 3-methylglutaconic Aciduria Type IV | Insulin Resistance | Hepatopulmonary Syndrome | Usher Syndrome Type IIC | Neuroectodermal Tumors, Primitive | Hamartoma | Long QT Syndrome Type 3 | Stroke | Leukocyte Adhesion Deficiency Type 1 | Carcinoid Syndrome | Erythrokeratodermia Variabilis | DEND Syndrome | Glanzmann Thrombasthenia | Polycystic Kidney, Autosomal Recessive | Bone Giant Cell Tumor | Hemangioblastoma | Carcinoma In Situ | Spinocerebellar Ataxia Type 6 | Stuttering | Acne Vulgaris | Keratocystic Odontogenic Tumor | Wiskott-Aldrich Syndrome | Riboflavin Transporter Deficiency Neuronopathy | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Infertility | Adrenomyeloneuropathy | Asthma, Exercise-induced | Sickle Cell Anemia | Molybdenum Cofactor Deficiency | Senior-Loken Syndrome | Encephalopathy, Ethylmalonic | Vestibular Disease | Uremia | Liver Failure, Acute Infantile | Filariasis | Maternally Inherited Diabetes And Deafness | Anemia | Bipolar Disorder | Harlequin Ichthyosis | Bloom Syndrome | Myocarditis | Diabetes Mellitus, Transient Neonatal | Chronic Myelomonocytic Leukemia | Demyelinating Diseases | Hypertension, Essential | Meniere's Disease | Steel Syndrome | Alopecia Totalis | Neurofibrosarcoma | Hermansky-Pudlak Syndrome | Retinoblastoma | Lassa Fever | Hypertensive Nephropathy | Borjeson-Forssman-Lehmann Syndrome | Hepatorenal Syndrome | Sleep Apnea, Obstructive | Acrocallosal Syndrome | Corneal Dystrophy And Perceptive Deafness | Epilepsy Of Infancy With Migrating Focal Seizures | Rolandic Epilepsy | Macrophagic Myofasciitis | Congenital Bilateral Absence Of Vas Deferens | Hemolytic Uremic Syndrome, Atypical | Leukoplakia | Sorsby Fundus Dystrophy | N-acetylglutamate Synthase Deficiency | Myotonia | Spinal Cord Diseases | Kearns-Sayre Syndrome | Spitzoid Melanoma | Sandhoff Disease | Myopathy | Pterygium | Retinal Degeneration | Pleomorphic Xanthoastrocytoma | Headache | LMNA-related Congenital Muscular Dystrophy | Chronic Beryllium Disease | Keratitis | Micropenis | Hypercholesterolemia, Familial | Lissencephaly 2 | Cervicitis | Weill-Marchesani Syndrome | Immunoproliferative Disorders | Encephalopathy | Prolymphocytic Leukemia | Pyruvate Dehydrogenase Deficiency | Hepatitis, Alcoholic | T-cell Lymphoma, Subcutaneous Panniculitis-like | Central Pain Syndrome | Congenital Mirror Movements | Vitreoretinopathy, Proliferative | Melanocytic Nevus | Cri-du-chat Syndrome | Aplastic Anemia | Carcinoma, Merkel Cell | Tylosis With Esophageal Cancer | Olmsted Syndrome | Otitis Externa | Hyperhomocysteinemia | Saul-Wilson Syndrome | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Cystinuria | Adenomatoid Tumor | Bare Lymphocyte Syndrome | Fahr Disease | Osteoglophonic Dysplasia | Anosmia, Congenital | Fanconi Syndrome | Noonan Syndrome | Connective Tissue Disorders | Hepatitis C, Chronic | Waardenburg Syndrome Type 2 | Spinocerebellar Ataxia Type 5 | Chronic Periodontitis | Pulverulent Zonular Cataract | Preaxial Polydactyly | Neurofibromatosis Type 2 | Fibrodysplasia Ossificans Progressiva | Leri-Weill Dyschondrosteosis | Macular Corneal Dystrophy | Niemann-Pick Disease, Type C | Congenital Generalized Lipodystrophy | AIDS | Rosacea | Thrombophilia | Lymphoproliferative Disease, X-linked | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Otosclerosis | Congenital Dyserythropoietic Anemia Type 4 | Crisponi Syndrome | Hemangioendothelioma | Pityriasis Rubra Pilaris | Angelman Syndrome | Multicystic Renal Dysplasia | Glaucoma | Poikiloderma With Neutropenia | Glaucoma, Congenital | Vaginitis | Diverticulitis | Myasthenia Gravis | Compartment Syndrome | Lathosterolosis | Hypertensive Retinopathy | Alazami Syndrome | Guanidinoacetate Methyltransferase Deficiency | Angiodysplasia | McLeod Syndrome | Aplasia Cutis Congenita | Graft-versus-host Disease | Mevalonate Kinase Deficiency | Isovaleric Acidemia | Carbamoyl Phosphate Synthetase I Deficiency | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Vertigo | Cousin Syndrome | Lichen Planus | Glycogen Storage Disease Type 9 | Hereditary Xerocytosis | Obesity, Morbid | Congestive Heart Failure | Alpha-mannosidosis | Esotropia | Alzheimer Disease, Late Onset | Tyrosinemia Type 2 | Long QT Syndrome Type 1 | Vascular Calcification | Non-Langerhans Cell Histiocytosis | Pineoblastoma | Spinocerebellar Ataxia Type 2 | Schwannoma | Avellino Corneal Dystrophy | Pyelonephritis | Hereditary Spherocytosis | Phosphoglycerate Dehydrogenase Deficiency | Leigh Syndrome | Tendinitis | Hepatic Steatosis | Syncope | Multiple Hamartoma Syndrome | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Gestational Trophoblastic Disease | Metabolic Diseases | Fibrillation, Atrial | Tricho-hepato-enteric Syndrome | Early Infantile Epileptic Encephalopathy 13 | Tangier Disease | Arthritis, Gouty | Delirium | Keratopathy | Cellulitis | Ectrodactyly | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Brachydactyly | Iron Metabolism Disorders | Glutaric Aciduria Type 3 | GNE Myopathy | Schnyder Crystalline Corneal Dystrophy | Metaphyseal Chondrodysplasia, Schmid Type | Premature Ejaculation | Peripheral Neuropathy | Greig Cephalopolysyndactyly Syndrome | Methemoglobinemia Type IV | Shprintzen-Goldberg Syndrome | Prader-Willi Syndrome | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Congenital Aniridia | Prediabetes | Inborn Errors Of Metabolism | Patent Ductus Arteriosus | Pneumonia, Bacterial | Porphyria, Acute Intermittent | Amenorrhea | Familial Mediterranean Fever | Meningioma, Benign | Triple A Syndrome | Leukoencephalopathy, Progressive Multifocal | Cenani-Lenz Syndactyly Syndrome | Withdrawal Syndrome | Combined Malonic And Methylmalonic Acidemia | Alveolar Capillary Dysplasia | Hypertrophy | Familial Male-limited Precocious Puberty | Pendred Syndrome | Dystonia Musculorum Deformans | Spondylocostal Dysostosis | Lymphoma, Follicular | Pericarditis