Disease

X-linked Hypohidrotic Ectodermal Dysplasia, XLHED

About the Disease
Ectodermal Dysplasia 1, Hypohidrotic, X-Linked, also known as christ-siemens-touraine syndrome, is related to ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive and anhidrosis, and has symptoms including dyspnea, dry skin and koilonychia. An important gene associated with Ectodermal Dysplasia 1, Hypohidrotic, X-Linked is EDA (Ectodysplasin A), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Wnt / Hedgehog / Notch. The drugs Antibodies and Immunoglobulins, Intravenous have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and spinal cord, and related phenotypes are everted lower lip vermilion and microdontia

Common Targets
EDA | IKBKG

疾病靶点研报
X-linked Hypohidrotic Ectodermal Dysplasia, XLHED

Note: If you'd like to get a target analysis report for X-linked Hypohidrotic Ectodermal Dysplasia, XLHED, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of X-linked Hypohidrotic Ectodermal Dysplasia, XLHED at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Congenital Adrenal Hyperplasia 1 | Spitzoid Melanoma | Best Macular Dystrophy | HANAC Syndrome | Fibrillation, Atrial | Purpura, Thrombotic Thrombocytopenic | Congenital Sodium Diarrhea | Hereditary Pyropoikilocytosis | Pyelonephritis | Cryptorchidism | Dysferlinopathy | Lichen Planus | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Hemolytic Uremic Syndrome, Atypical | Addison Disease | Alazami Syndrome | Encephalitis, Tick-borne | Melanocytic Nevus | Corneal Edema | Influenza | Conjunctivitis | Renpenning Syndrome | TARP Syndrome | Hypohidrotic Ectodermal Dysplasia, X-linked | Hennekam Lymphangiectasia-lymphedema Syndrome | Progressive Familial Intrahepatic Cholestasis Type 2 | Calcium Pyrophosphate Deposition Disease | Aplasia Cutis Congenita | Anterior Segment Dysgenesis | Amyloidosis | Rheumatic Heart Disease | Inflammatory Myofibroblastic Tumor | Subcortical Band Heterotopia | Desbuquois Syndrome | Retinal Dystrophy | Congenital Bilateral Absence Of Vas Deferens | Occipital Neuralgia | Relapsing Polychondritis | Mevalonate Kinase Deficiency | Focal Cortical Dysplasia Type 2 | Sjogren Syndrome | H Syndrome | Endophthalmitis | Early Infantile Epileptic Encephalopathy 13 | Ophthalmoplegia | Epidermal Nevus Syndrome | Liebenberg Syndrome | Progressive Familial Intrahepatic Cholestasis Type 3 | Anovulation | Spinocerebellar Ataxia Type 28 | Cholangiocarcinoma | Charcot-Marie-Tooth Disease Type 4B1 | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Cornelia De Lange Syndrome | Sepiapterin Reductase Deficiency | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Thyroid Dyshormonogenesis | Alexander Disease | Plasmacytoma | Anuria | Hepatic Veno-occlusive Disease | Lissencephaly 2 | Angelman Syndrome | Spinocerebellar Ataxia Type 8 | Pitt-Hopkins Syndrome | Spondyloperipheral Dysplasia | Cavitary Optic Disc Anomalies | Sengers Syndrome | Paraganglioma, Carotid Body | Arterial Tortuosity Syndrome | Perry Syndrome | Focal Segmental Glomerulosclerosis | Micropenis | Chondrodysplasia Punctata 2, X-linked Dominant | Silver-Russell Syndrome | Dementia, Vascular | Leukemia | Double Outlet Right Ventricle | Pleurisy | Waardenburg Syndrome Type 4 | Lichen Sclerosus | Portal Vein Thrombosis | Psoriasis | Whipple's Disease | Neuroleptic Malignant Syndrome | Nemaline Myopathy | VEXAS Syndrome | Glycogen Storage Disease Type 1a | Hemochromatosis Type 1 | Ameloblastoma | Neurodegeneration With Brain Iron Accumulation | Nijmegen Breakage Syndrome | Dysthymia | Adrenomyeloneuropathy | Myofibromatosis | Pneumonia, Bacterial | Macular Degeneration | Pfeiffer Syndrome | Renal Tubular Dysgenesis | DOCK8 Immunodeficiency Syndrome | Schizophrenia | T-cell Prolymphocytic Leukemia | Basal Ganglia Disease | Keratoconjunctivitis | Chitayat Syndrome | Plasma Cell Dyscrasia | Familial Partial Lipodystrophy | Intestinal Hypomagnesemia 1 | Pityriasis Rubra Pilaris | Long QT Syndrome Type 3 | Mabry Syndrome | CHARGE Syndrome | Jawad Syndrome | Oligodendroglioma | Ganglioneuroma | Cystitis | Cyst | Leukoplakia | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Aspartylglycosaminuria | Down Syndrome | Central Retinal Artery Occlusion | Cat Eye Syndrome | Peritonitis | Eating Disorder | Lipodystrophy | Charcot-Marie-Tooth Disease Type 4 | Granuloma Annulare | Spondylometaphyseal Dysplasia | Neuronal Ceroid Lipofuscinosis | Chanarin-Dorfman Syndrome | L-2-Hydroxyglutaric Aciduria | Congenital Fiber-type Disproportion Myopathy | Primary Erythromelalgia | Spinocerebellar Ataxia | Heart Block | Benign Familial Pemphigus | Meningeal Melanocytoma | Hydrolethalus Syndrome | Ollier Disease | Headache | Colitis, Microscopic | Turner's Syndrome | Myocarditis | Celiac Disease | Adenoma, Villous | Methylmalonic Acidemia | Hyperammonemia | DICER1 Syndrome | Ligneous Conjunctivitis | Stomatitis | Dermatofibrosarcoma | Camptocormia | Vulvovaginitis | AIDS | Neuroendocrine Cancer | Congenital Dyserythropoietic Anemia | Meningococcal Infections | Dowling-Degos Disease | Parkinson's Disease | Pseudohypoaldosteronism | Milk Allergy | Aarskog-Scott Syndrome | Pontocerebellar Hypoplasia Type 7 | Gigantism | Personality Disorders | Diffuse Palmoplantar Keratoderma | Glycogen Storage Disease Type 4 | Tonsillitis | Chronic Granulomatous Disease, X-linked | Schnitzler Syndrome | Wolfram Syndrome | Systemic Lupus Erythematosus | Congenital Nephrotic Syndrome | Osteoporosis-pseudoglioma Syndrome | Dupuytren Disease | Hepatorenal Syndrome | Transcobalamin Deficiency | Cheilitis | Hypervalinemia | Myelodysplasia | Leiomyoma | Progressive External Ophthalmoplegia | Tinea | Stromal Corneal Dystrophy | Achondrogenesis | Brachial Plexus Neuropathy | Sleep Apnea | Homocystinuria | Leber Congenital Amaurosis | Polymyalgia Rheumatica | Greenberg Dysplasia | Dystrophy, Cone-rod | B-cell Prolymphocytic Leukemia | Renal Hypomagnesemia 3 | Rash | Platelet Disorders | Cabezas Syndrome | Acne Vulgaris | Osteogenesis Imperfecta Type V | Antiphospholipid Syndrome | Senior-Loken Syndrome | Schistosomiasis | Yellow Fever | Juvenile Hyaline Fibromatosis | Choroideremia | Heart Failure | Low Tension Glaucoma | Angiodysplasia | Vogt-Koyanagi-Harada Syndrome | Proteus Syndrome | Deafness, Dystonia, And Cerebral Hypomyelination | Schaaf-Yang Syndrome | Uremia | Rubinstein-Taybi Syndrome | Raine Syndrome | Agammaglobulinemia | Diabetes Type 1 | Loeys-Dietz Syndrome Type 4 | Hepatitis | Nail-Patella Syndrome | Porphyria Cutanea Tarda | Hypertension, Renal | Carcinoid Tumor | Retinopathy, Diabetic | Erythrokeratodermia Variabilis | Renal Dysplasia | Carbohydrate Metabolism Disorders | Rotor Syndrome | Early Infantile Epileptic Encephalopathy | Retinal Telangiectasia | Familial Mediterranean Fever | Holoprosencephaly | Cryptococcal Meningitis | Wiedemann-Steiner Syndrome | Bethlem Myopathy | Chordoid Glioma | Constipation | Transient Bullous Dermolysis Of The Newborn | Tularemia | Chondrodysplasia Punctata 1, X-linked Recessive | Brenner Tumor | Primary Hyperoxaluria Type 1 | Tietze Syndrome | Herpes Simplex Dermatitis | C3 Glomerulopathy | Pyruvate Kinase Deficiency | Rhabdomyosarcoma, Alveolar | Fibrodysplasia Ossificans Progressiva | Motion Sickness | Creatine Deficiency Syndrome Due To AGAT Deficiency | Macrophage Activation Syndrome | Encephalopathy, Hepatic | Majeed Syndrome | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Cleidocranial Dysplasia | Cancer, Skin | Fanconi Anemia | Chronic Lymphocytic Leukemia | Premenstrual Syndrome | Hepatic Steatosis | Epidermolytic Ichthyosis, Annular | Postpartum Depression | Acute Myeloid Leukemia | Peripheral T-cell Lymphoma | Axenfeld-Rieger Syndrome | Sarcoidosis, Pulmonary | Malaria, Cerebral | Apparent Mineralocorticoid Excess Syndrome | Rosacea | Tetanus | Inborn Errors Of Metabolism | Nicolaides-Baraitser Syndrome | Pre-eclampsia | Primary Ovarian Insufficiency | Iron Overload | Microphthalmia, Syndromic 7 | Hypercholesterolemia | Gastroenteritis | 3-hydroxy-3-methylglutaric Aciduria | Charcot-Marie-Tooth Disease | Mastitis | Otitis Externa | Communication Disorders | Optic Neuropathy | Sarcoma, Ewing | Takenouchi-Kosaki Syndrome | Neurodermatitis | Krabbe Disease | Meningococcal Meningitis | Essential Fructosuria | Pulmonary Veno-occlusive Disease | Cervical Dystonia | Lyme Disease | Neurotoxicity | CDKL5 Deficiency Disorder | Budd-Chiari Syndrome | Lymphangioma | Tuberculosis | Nephrotic Syndrome Type 1 | Chiari Malformation Type I | Glycogen Storage Disease Type 3 | Schnyder Crystalline Corneal Dystrophy | Skin Papilloma | Osteopathia Striata With Cranial Sclerosis | Neuromuscular Disorders | Spinocerebellar Ataxia Type 6 | Basal Ganglia Cerebrovascular Disease | Esophageal Adenocarcinoma | Bronchiolitis | Pheochromocytoma | Peutz-Jeghers Syndrome | Wieacker-Wolff Syndrome | Niemann-Pick Disease | Molybdenum Cofactor Deficiency | Atopy | Acute Coronary Syndrome | Temporal Lobe Epilepsy | Sarcomatoid Carcinoma Of The Lung | IgA Deficiency | Prader-Willi Syndrome | Coronary Restenosis | Retinoschisis | Wiskott-Aldrich Syndrome | Coloboma | Steel Syndrome | Central Core Disease | Leiomyosarcoma | Hypoproteinemia, Hypercatabolic | Urticaria | Cranial Nerve Disease | Snyder-Robinson Syndrome | Phenylketonuria | Carcinoma, Small Cell | Empyema | Hyperinsulinemia | Metachondromatosis | Barakat Syndrome | Necrotizing Autoimmune Myopathy | Keratitis-ichthyosis-deafness Syndrome | Potocki-Shaffer Syndrome | Eclampsia | Poretti-Boltshauser Syndrome | Haim-Munk Syndrome | Vitreoretinopathy, Proliferative | Usher Syndrome Type III | Charcot-Marie-Tooth Disease, Type 2A | Pituitary Disorders | Riboflavin Transporter Deficiency Neuronopathy | Episodic Ataxia Type 2 | Multifocal Motor Neuropathy | Hypersomnia | Autoimmune Hemolytic Anemia | Iron Deficiency Anemia | DEND Syndrome | Periodontitis | Neuromyelitis Optica | Schizophrenia, Paranoid | Inflammatory Myopathy | Metatropic Dysplasia | Alopecia | Lymphoma | Primary Torsion Dystonia | Hypotrichosis | Nicotine Addiction | GATA2 Deficiency | Microtia | Biotinidase Deficiency | Sponastrime Dysplasia | Osteonecrosis | Hyperthyroidism | Peeling Skin Syndrome Type B | GLUT1 Deficiency Syndrome | Spinal Muscular Atrophy Type 2 | Hyperparathyroidism, Primary | Obesity | Varices | Renal Failure | Osteosarcoma | Delirium | CREST Syndrome | Dyslexia | Congenital Disorders Of Glycosylation | Rheumatoid Arthritis | Cantu Syndrome | Thrombophilia | Acrodysostosis | Gyrate Atrophy Of The Choroid And Retina | Intestinal Tuberculosis | Benign Familial Infantile Seizures | Focal Facial Dermal Dysplasia | Angiosarcoma | Hypertension, Pulmonary | Costello Syndrome | Aromatic L-amino Acid Decarboxylase Deficiency | Lassa Fever | Epidermolysis Bullosa Simplex, Localized | Insulinoma | Cartilage Disorders | Blomstrand Osteochondrodysplasia