Granular Corneal Dystrophy Type 1

About the Disease
Corneal Dystrophy, Groenouw Type I, also known as cdgg1, is related to corneal dystrophy and corneal dystrophy, reis-bucklers type. An important gene associated with Corneal Dystrophy, Groenouw Type I is TGFBI (Transforming Growth Factor Beta Induced), and among its related pathways/superpathways are Keratan sulfate biosynthesis and Articular Cartilage Extracellular Matrix. Affiliated tissues include cornea and eye, and related phenotypes are corneal crystals and central corneal dystrophy

Common Targets
TGFBI

Note: If you'd like to get a target analysis report for Granular Corneal Dystrophy Type 1, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Granular Corneal Dystrophy Type 1 at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Neonatal Progeroid Syndrome | Ellis-Van Creveld Syndrome | X-linked Creatine Transporter Deficiency | Restrictive Dermopathy | Facioscapulohumeral Muscular Dystrophy | Familial Male-limited Precocious Puberty | Postaxial Polydactyly | Angina Pectoris | Mumps | Fibromuscular Dysplasia | Epidermolysis Bullosa Acquisita | IgA Deficiency | Pontocerebellar Hypoplasia Type 2 | Hypersomnia | Peeling Skin Syndrome, Acral Type | Inflammatory Bowel Disease | Hypothyroidism | Chylothorax, Congenital | Potocki-Shaffer Syndrome | Herpes Genitalis | Joubert Syndrome | Pterygium | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Anuria | Echinococcosis | Hepatitis, Autoimmune | Schizencephaly | Danon Disease | Brugada Syndrome 1 | Skin Papilloma | Intellectual Disability, Autosomal Dominant 5 | Anterior Segment Dysgenesis | Giant Axonal Neuropathy | Acanthosis Nigricans | Adams-Oliver Syndrome | Alkaptonuria | Malaria, Cerebral | Hyperammonemia | Osteochondrosis | Hennekam Lymphangiectasia-lymphedema Syndrome | Chromosome 8q21.11 Deletion Syndrome | Multiple Epiphyseal Dysplasia | Blood Protein Disorders | Torticollis | Woodhouse-Sakati Syndrome | Melanocytic Nevus | Hashimoto Thyroiditis | Spinocerebellar Ataxia Type 8 | Bronchiectasis | Temtamy Preaxial Brachydactyly Syndrome | Lymphoma, Follicular | Congenital Bilateral Absence Of Vas Deferens | Martsolf Syndrome | Craniosynostosis | Avellino Corneal Dystrophy | Achromatopsia | Astigmatism | Intestinal Tuberculosis | Orotic Aciduria | Periventricular Nodular Heterotopia | Long QT Syndrome Type 2 | Costello Syndrome | Patent Foramen Ovale | Neuromyelitis Optica | Glycogen Storage Disease | Carney-Stratakis Syndrome | Osteoporosis-pseudoglioma Syndrome | McLeod Syndrome | DEND Syndrome | Osmotic Demyelination Syndrome | Desbuquois Syndrome | Albinism | Progressive Encephalopathy-optic Atrophy Syndrome | Renal Medullary Carcinoma | Basal Ganglia Disease, Biotin-responsive | Dysmorphophobia | Hypertension, Renovascular | Osteoporosis | Short-chain Acyl-CoA Dehydrogenase Deficiency | Jalili Syndrome | Hypertriglyceridemia | Familial Digital Arthropathy-brachydactyly | Cryptococcal Meningitis | Oculocutaneous Albinism Type 1 | Autonomic Neuropathy | Barrett Esophagus | Antenatal Bartter Syndrome Type 1 | Neovascular Glaucoma | Hyperostosis | Progressive Familial Intrahepatic Cholestasis | Dominant Optic Atrophy | Stroke | Dyslipidemia | Primary Cutaneous Amyloidosis | 3-methylglutaconic Aciduria Type I | Epidermolytic Ichthyosis, Annular | Galloway-Mowat Syndrome | Paraganglioma, Carotid Body | Cone Dystrophy | Guanidinoacetate Methyltransferase Deficiency | Large Granular Lymphocytic Leukemia | Usher Syndrome Type II | Ovarian Hyperstimulation Syndrome | Migraine | Epidermal Nevus Syndrome | Twin-to-twin Transfusion Syndrome | Wolfram Syndrome 2 | Urofacial Syndrome | Corneal Neovascularization | Cousin Syndrome | Acute Leukemia | Multiple Sulfatase Deficiency | Cenani-Lenz Syndactyly Syndrome | Hyperoxaluria | Androgen Insensitivity | Multicystic Renal Dysplasia | Paracoccidioidomycosis | Chondrodysplasia Punctata 1, X-linked Recessive | Patent Ductus Arteriosus | Oculocutaneous Albinism | McCune-Albright Syndrome | Vertebrobasilar Insufficiency | Zollinger-Ellison Syndrome | Abetalipoproteinemia | Takotsubo Cardiomyopathy | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Nicolaides-Baraitser Syndrome | Phenylketonuria II | Hemorrhagic Disorders | Renal Hypomagnesemia 3 | Poretti-Boltshauser Syndrome | Leri Pleonosteosis | Osteosarcoma | Erythema Nodosum | Wieacker-Wolff Syndrome | Melanoma | Miyoshi Myopathy | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Thyroid Dysgenesis | Spinocerebellar Ataxia Type 42 | Osteogenesis Imperfecta Type IV | Charcot-Marie-Tooth Disease, Type 2C | Ectopia Lentis, Isolated, Autosomal Recessive | Autosomal Recessive Spastic Paraplegia Type 54 | Congenital Lipoid Adrenal Hyperplasia | Presbycusis | Mitochondrial Cytopathy | Hartnup Disease | Arthritis, Psoriatic | Adenomatoid Tumor | Cancer, Brain | Pulmonary Tuberculosis | Erythrokeratodermia Variabilis | Endophthalmitis | Stomatitis | Cellulitis | Stargardt Disease | Phenylketonuria | Nephroblastoma | Hereditary Hemorrhagic Telangiectasia Type 2 | Hepatitis E | Cantu Syndrome | Angiosarcoma | Multiple Sclerosis, Secondary Progressive | Glioblastoma Multiforme | Leishmaniasis, Visceral | Acral Lentiginous Melanoma | FG Syndrome | Alpers Syndrome | Gray Platelet Syndrome | X-linked Myotubular Myopathy | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Progressive Myoclonic Epilepsy | Low Tension Glaucoma | Maternally Inherited Diabetes And Deafness | Arts Syndrome | Meningitis | Colitis | Neuroectodermal Tumors, Primitive | Parkinsonism | Retinitis | Central Pain Syndrome | Asthma, Nocturnal | Focal Cortical Dysplasia Type 2 | Keratitis | Genitopatellar Syndrome | Hypertension, Portal | Oral Lichen Planus | Hepatoblastoma | Interstitial Lung Diseases | Atopic Dermatitis | Dubin-Johnson Syndrome | Chromosome 5q Deletion Syndrome | Focal Facial Dermal Dysplasia | Fanconi Syndrome | Osteomyelitis | Strabismus | Metabolic Diseases | Obesity | X-linked Acrogigantism | Meningioma, Benign | Noonan Syndrome-like Disorder With Loose Anagen Hair | Hypermetropia | Castleman Disease | Neuroleptic Malignant Syndrome | Osteoporosis, Postmenopausal | Steel Syndrome | Lymphomatoid Granulomatosis | Autosomal Recessive Congenital Ichthyosis | Waardenburg Syndrome Type 2 | Common Variable Immunodeficiency | Neurofibromatosis Type 2 | Congenital Generalized Lipodystrophy | Proopiomelanocortin Deficiency | Leukocyte Adhesion Deficiency Type 1 | Sarcoma, Ewing | Leukoplakia, Oral | Early Infantile Epileptic Encephalopathy 28 | Cold-induced Sweating Syndrome | Glycogen Storage Disease Type 1a | Leri-Weill Dyschondrosteosis | Orthostatic Intolerance | Congenital Dyserythropoietic Anemia Type 4 | Neurocutaneous Syndromes | Van Der Knaap Disease | Evans Syndrome | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Bare Lymphocyte Syndrome | Polycystic Ovary Syndrome | Cushing Syndrome | Withdrawal Syndrome | Congenital Fiber-type Disproportion Myopathy | Methemoglobinemia | Uterine Leiomyoma | Allan-Herndon-Dudley Syndrome | Basan Syndrome | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Tyrosinemia Type 1 | Neurofibrosarcoma | Facioscapulohumeral Muscular Dystrophy Type 1 | Congenital Hereditary Endothelial Dystrophy Type II | Gastroschisis | Axenfeld-Rieger Syndrome | Carbohydrate Metabolism Disorders | Lathosterolosis | Farber Disease | Cavitary Optic Disc Anomalies | Borjeson-Forssman-Lehmann Syndrome | Lymphangioleiomyomatosis | Pityriasis Rubra Pilaris | Pendred Syndrome | Homocystinuria | Osteogenesis Imperfecta Type V | Protein S Deficiency | Chondromyxoid Fibroma | Oligoasthenoteratozoospermia | Uveitis, Anterior | Prediabetes | Hemorrhage | Progressive External Ophthalmoplegia | Heart Septal Defects | Dental Caries | Adenoid Cystic Carcinoma | Brachydactyly | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Diabetes Type 1 | Erythematotelangiectatic Rosacea | Myoclonus-dystonia Syndrome | Purpura, Thrombotic Thrombocytopenic | Thrombocythemia, Essential | Bloom Syndrome | Hemoglobinopathies | Shock, Cardiogenic | Early Infantile Epileptic Encephalopathy 13 | Blepharospasm | Myelomeningocele | Odonto-onycho-dermal Dysplasia | Exotropia | Fibrillation, Atrial | Dysgerminoma | Duodenal Atresia | Congenital Primary Aphakia | DRESS Syndrome | Hypertelorism | Glycogen Storage Disease Type 1b | Sjogren Syndrome | Pfeiffer Syndrome | Erdheim-Chester Disease | Rhizomelic Chondrodysplasia Punctata | Cholera | Glycogen Storage Disease Type 6 | NDH Syndrome | Charcot-Marie-Tooth Disease Type 2D | Hypopituitarism | Early Infantile Epileptic Encephalopathy 1 | Viral Meningitis | Hartsfield Syndrome | Nestor-Guillermo Progeria Syndrome | Spinocerebellar Ataxia Type 23 | Wolcott-Rallison Syndrome | Asphyxia Neonatorum | Autoimmune Disease | T-cell Chronic Lymphocytic Leukemia | Congenital Dyserythropoietic Anemia Type 1 | Encephalopathy, Glycine | Acromesomelic Dysplasia | Hypertension, Essential | Klippel-Feil Syndrome | Psoriasis | Bulimia Nervosa | Pneumonia, Viral | Gaucher Disease | Johanson-Blizzard Syndrome | Diabetes Gestational | Neurogenic Bladder | Sorsby Fundus Dystrophy | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Osteonecrosis | Cholestasis, Intrahepatic | Peritonitis | Blue Rubber Bleb Nevus Syndrome | Left Ventricular Noncompaction | Takayasu's Arteritis | Chromosome 17q21.31 Deletion Syndrome | Myoclonic Epilepsy With Ragged Red Fibers | Antisynthetase Syndrome | Fetal Akinesia Deformation Sequence | Glaucoma, Congenital | Methylmalonic Acidemia | Pneumonia, Bacterial | Osteochondroma | Optic Nerve Diseases | Leber Congenital Amaurosis | Dysfibrinogenemia | Familial Thoracic Aortic Aneurysm | 5-oxoprolinase Deficiency | Usher Syndrome Type III | Babesiosis | Spasticity | Ligneous Conjunctivitis | Kidney Stones | Melanoma, Uveal | Primary Progressive Aphasia | Schwannomatosis | Pancytopenia | Mastitis | Chorea-acanthocytosis | Hypolipoproteinemia | Spondylo-ocular Syndrome | Persistent Truncus Arteriosus | Oligospermia | Localized Scleroderma | Seizures | Hyperparathyroidism | Congenital Mirror Movements | Polymyalgia Rheumatica | Arthropathy | Waardenburg Syndrome | Leukemia | DOCK8 Immunodeficiency Syndrome | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Learning Disability | Pemphigus | Charcot-Marie-Tooth Disease Axonal Type 2N | Histiocytosis | Pancreatitis, Chronic | Disseminated Superficial Actinic Porokeratosis | Necrobiosis Lipoidica | Familial Hypobetalipoproteinemia | Pitt-Hopkins Syndrome | Conjunctivitis | Premenstrual Syndrome | Beta-Propeller Protein-associated Neurodegeneration | Oculodentodigital Dysplasia | Pericarditis | Schizophrenia, Paranoid | Prolidase Deficiency | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Peters-plus Syndrome | Seminoma | Preaxial Polydactyly | Ganglioglioma | GATA2 Deficiency | Sick Sinus Syndrome | Early Infantile Epileptic Encephalopathy | Fibrosarcoma | Tinea Versicolor | Myasthenia | Cardiomyopathy, Dilated, 1L | Congenital Central Hypoventilation Syndrome | Varicocele | Hyperparathyroidism, Secondary | Whipple's Disease | Hereditary Pyropoikilocytosis | Myositis, Focal | Fucosidosis | Heimler Syndrome | Cancer, Prostate | Pneumonia, Mycoplasma | Herpes Simplex Dermatitis