Hemoglobinopathies

About the Disease
Hemoglobinopathy, also known as hemoglobinopathies, is related to methemoglobinemia, beta-globin type and heinz body anemias, and has symptoms including cyanosis An important gene associated with Hemoglobinopathy is HBB (Hemoglobin Subunit Beta), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and HIF-1-alpha transcription factor network. The drugs Ribavirin and Peginterferon alfa-2b have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, t cells and bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Common Targets
DNA-Directed RNA Polymerase (nonspecified subtype) | PRMT5 | BCL11A | RIOK3 | EED | TMPRSS6 | KLF10 | HLA-L | KDM1A | G196 | HBA1 | G1786 | MTARC2 | HBA2 | HBB | EPOR | ZNF410 | Polycomb Repressive Complex 2 | KLF1 | HDAC6 | HBG1 | SIN3A | HBG2 | GPR83 | HDAC2 | SEC31B | G7124 | CD5 | Monoamine oxidase (MAO) (nonspecified subtype) | HDAC1 | DDC | ICOS | SERPINF1 | ATRX

Note: If you'd like to get a target analysis report for Hemoglobinopathies, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hemoglobinopathies at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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