Charcot-Marie-Tooth Disease Type 3

About the Disease
Hypertrophic Neuropathy of Dejerine-Sottas, also known as dejerine-sottas disease, is related to charcot-marie-tooth disease, demyelinating, type 4f and charcot-marie-tooth disease, demyelinating, type 1b, and has symptoms including ataxia, sensory An important gene associated with Hypertrophic Neuropathy of Dejerine-Sottas is MPZ (Myelin Protein Zero), and among its related pathways/superpathways are Neural crest differentiation and EGR2 and SOX10-mediated initiation of Schwann cell myelination. Affiliated tissues include tongue, dorsal root ganglion and spinal cord, and related phenotypes are nystagmus and scoliosis

Common Targets
SH3TC2 | PRX | SACS

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