Gardner Syndrome

About the Disease
Familial Adenomatous Polyposis 1, also known as gardner syndrome, is related to apc-associated polyposis conditions and mismatch repair cancer syndrome 1, and has symptoms including abdominal pain and diarrhea. An important gene associated with Familial Adenomatous Polyposis 1 is APC (APC Regulator Of WNT Signaling Pathway). The drugs Azithromycin and Erythromycin have been mentioned in the context of this disorder. Affiliated tissues include colon, brain and skin, and related phenotypes are brain neoplasm and colon cancer

Common Targets
G4089 | POLE | MUTYH | BMPR1A | APC

Note: If you'd like to get a target analysis report for Gardner Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Gardner Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Tricho-hepato-enteric Syndrome | Hemangioendothelioma | Von Hippel-Lindau Disease | Tendinopathy | Familial Hyperaldosteronism | Eccrine Porocarcinoma | Thrombosis | Goiter, Nodular | Turner's Syndrome | Chondroma | Anorectal Malformations | Cryptococcal Meningitis | Renal-hepatic-pancreatic Dysplasia | Charcot-Marie-Tooth Disease Type 4B1 | Poirier-Bienvenu Neurodevelopmental Syndrome | Atelosteogenesis Type 2 | Pregnancy, Ectopic | Lymphangioma | Ectodermal Dysplasia | Congenital Hypofibrinogenemia | Hyperthyroidism | Necrobiosis Lipoidica | Endocarditis | Papilloma | Netherton Syndrome | Lichen Sclerosus | Toxic Epidermal Necrolysis | Proximal Symphalangism | ACTH-independent Macronodular Adrenal Hyperplasia | Holt-Oram Syndrome | Leukemia-lymphoma, Adult T-cell | Cerebellofaciodental Syndrome | Osteonecrosis | Panic Disorder | Autonomic Neuropathy | Panuveitis | T-cell Prolymphocytic Leukemia | Diarrhea | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Hepatitis B, Chronic | Thanatophoric Dysplasia | Rhabdomyosarcoma, Alveolar | Diabetic Encephalopathy | Eczema | Galloway-Mowat Syndrome | Acne | Adams-Oliver Syndrome | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Inflammatory Myofibroblastic Tumor | Osteoporosis-pseudoglioma Syndrome | Micropenis | Progressive Myoclonic Epilepsy | 3-methylcrotonyl-CoA Carboxylase Deficiency | Robinow Syndrome | Chronic Lymphocytic Leukemia | Porphyria, Acute Intermittent | Cyst | Retinal Diseases | Spinocerebellar Ataxia Type 28 | Chromosome 8q21.11 Deletion Syndrome | Stromal Corneal Dystrophy | Congenital Adrenal Hyperplasia 1 | Blepharophimosis Syndrome | Juvenile Myoclonic Epilepsy | Cardiomyopathy, Hypertrophic | Whipple's Disease | Stuve-Wiedemann Syndrome | Melnick-Needles Syndrome | Conduct Disorder | Loeys-Dietz Syndrome | Congenital Nystagmus | Fabry's Disease | Corneal Dystrophy And Perceptive Deafness | Vitamin K Deficiency | Hairy Cell Leukemia | Mitochondrial Disease | Osteochondrosis | Osteogenesis Imperfecta Type VI | Osteogenesis Imperfecta Type II | Blepharospasm | Renal Tubular Dysgenesis | Blood Protein Disorders | Myasthenia Gravis | Infantile Nephropathic Cystinosis | Niemann-Pick Disease, Type C | Encephalopathy | NDH Syndrome | Hepatitis C, Chronic | Angiomyolipoma | Rett Syndrome | Oculocutaneous Albinism Type 2 | Trichuriasis | Familial Exudative Vitreoretinopathy | Hypertension, Renal | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Amish Infantile Epilepsy Syndrome | Glutaric Aciduria Type 3 | Congenital Primary Aphakia | Sick Sinus Syndrome | Leukodystrophies | Vitamin B12 Deficiency | Cat Eye Syndrome | Beckwith-Wiedemann Syndrome | Acute Coronary Syndrome | Alpha-1 Antitrypsin Deficiency | Empyema | Spinal Muscular Atrophy Type 2 | Neurocutaneous Melanocytosis | Dyskeratosis Congenita | Bladder Exstrophy | Hyperferritinemia-cataract Syndrome | Amyloidosis | Thanatophoric Dysplasia Type 1 | Pyloric Stenosis, Infantile Hypertrophic | Bartsocas-Papas Syndrome | Paroxysmal Kinesigenic Dyskinesia | Inflammatory Myopathy | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Cold Agglutinin Disease | Cardiomyopathy, Restrictive | Hyperkalemic Periodic Paralysis | Mosaic Variegated Aneuploidy Syndrome 2 | Glaucoma, Congenital | Polyneuropathy | Pneumoconiosis | B-cell Prolymphocytic Leukemia | Hepatitis, Chronic | Pseudohermaphroditism | Delayed Sleep Phase Syndrome | Neurofibroma, Plexiform | Atelosteogenesis Type 1 | Pilomatrix Carcinoma | Esthesioneuroblastoma | Atopic Dermatitis | Peters-plus Syndrome | Wieacker-Wolff Syndrome | Spitz Nevus | Frontotemporal Dementia | GATA2 Deficiency | Thrombotic Microangiopathy | Neurofibromatosis Type 1 | Hemorrhage | X-linked Acrogigantism | Hemochromatosis | Liver Diseases | Lymphoma, AIDS-related | Cabezas Syndrome | Hypertensive Retinopathy | Cystitis | Metabolic Diseases | Esophagitis, Eosinophilic | Bipolar Disorder | Molybdenum Cofactor Deficiency | Ganglioneuroma | Demyelinating Diseases | Dowling-Degos Disease | Acrocallosal Syndrome | Otopalatodigital Syndrome Type 2 | Keratosis | Dysmorphophobia | Primary Familial Brain Calcification | Duchenne Muscular Dystrophy | Krabbe Disease | Prediabetes | Kallmann Syndrome | Tylosis With Esophageal Cancer | Ovarian Hyperstimulation Syndrome | Ollier Disease | GLUT1 Deficiency Syndrome | Leiomyosarcoma | Hyperparathyroidism | Pituitary Dwarfism | Odonto-onycho-dermal Dysplasia | Paraplegia | Generalized Epilepsy And Paroxysmal Dyskinesia | Oligoasthenoteratozoospermia | Neuroendocrine Cancer | Transient Bullous Dermolysis Of The Newborn | Retinopathy Of Prematurity | Acute Anterior Uveitis | Nail Disorder, Nonsyndromic Congenital | Carcinoid Syndrome | Pierre Robin Syndrome | GAPO Syndrome | Methemoglobinemia | Tibial Muscular Dystrophy | Giant Cell Glioblastoma | Thrombocytopenia | Pterygium | Acute Leukemia | Prurigo Nodularis | CHOPS Syndrome | Cholera | Trichomegaly | Osteopathia Striata With Cranial Sclerosis | VACTERL Association | Craniopharyngioma | Heterotopic Ossification | Fanconi Syndrome | Combined Malonic And Methylmalonic Acidemia | McCune-Albright Syndrome | Hypoproteinemia, Hypercatabolic | Pouchitis | Cancer, Skin | Intermittent Explosive Disorder | Camurati-Engelmann Disease | Meningioma | Ulcerative Colitis | Paronychia | Cholesteryl Ester Storage Disease | Citrullinemia | Hereditary Hemorrhagic Telangiectasia Type 2 | Nanophthalmos | Erectile Dysfunction | Absence Epilepsy | Hyperparathyroidism-jaw Tumor Syndrome | Anosmia, Congenital | Limb Girdle Muscular Dystrophy | Ichthyosis | Hereditary Mixed Polyposis Syndrome | Cardiac Sarcoidosis | Alexander Disease | Corneal Dystrophies, Hereditary | Congenital Heart Defects | Pelvic Inflammatory Disease | Paraganglioma, Carotid Body | Bainbridge-Ropers Syndrome | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Multiple Sulfatase Deficiency | Cardiospondylocarpofacial Syndrome | Aarskog-Scott Syndrome | Martsolf Syndrome | Pfeiffer Syndrome | Hyperlipidemia, Familial Combined | Pendred Syndrome | Neuropathy | Gastritis, Atrophic | Trismus-pseudocamptodactyly Syndrome | Infectious Diarrhea | Pericarditis | Marfan Syndrome | Hepatorenal Syndrome | Lupus Erythematosus | Gallstones | Common Cold | Cholangitis | Autonomic Nervous System Disorders | Leri Pleonosteosis | Blepharitis | Choroiditis | Smoldering Myeloma | Spitzoid Melanoma | Apraxia | Lymphoma, B-cell | Distal Myopathy 2 | Non-epidermolytic Palmoplantar Keratoderma | Sensorineural Hearing Loss | Bethlem Myopathy | Ligneous Conjunctivitis | Scabies | Pityriasis Rubra Pilaris | Gout | Presbycusis | Familial Partial Lipodystrophy | Zollinger-Ellison Syndrome | Facioscapulohumeral Muscular Dystrophy | Scleroderma, Diffuse | Aphasia | Diabetes Insipidus, Neurogenic | Ichthyosis Bullosa Of Siemens | Thymoma, Malignant | Jacobsen Syndrome | Diverticulitis | Angioedema | Neurogenic Bladder | Migraine | Autosomal Recessive Spastic Paraplegia Type 54 | Cold-induced Sweating Syndrome | Carcinoid Tumor | Lipid Metabolism Disorders | Fibronectin Glomerulopathy | Arts Syndrome | Methylmalonic Acidemia | VACTERL/VATER Association | Phenylketonuria | X-linked Sideroblastic Anemia | Corneal Neovascularization | Kidney Stones | Cirrhosis | Chronic Myeloid Leukemia | Angiodysplasia | Hemorrhoids | Esophageal Motility Disorders | Cavitary Optic Disc Anomalies | Uveitis, Anterior | Autoimmune Hemolytic Anemia | Peeling Skin Syndrome, Acral Type | Creutzfeldt-Jakob Disease | Congenital Hereditary Endothelial Dystrophy Type I | Pyruvate Carboxylase Deficiency Disease | Lewy Body Dementia | Sclerosing Cholangitis | Congenital Lipoid Adrenal Hyperplasia | Persistent Fetal Circulation | Charcot-Marie-Tooth Disease Axonal Type 2N | Fetal And Neonatal Alloimmune Thrombocytopenia | Hyperkeratosis | Polydactyly | Zygomycosis | Alopecia | Niemann-Pick Disease, Type A | Epiphyseal Chondrodysplasia, Miura Type | Hereditary Sensory And Autonomic Neuropathy | Sclerocornea | Spinocerebellar Ataxia Type 8 | Usher Syndrome Type III | Early Infantile Epileptic Encephalopathy 13 | Exostoses | Priapism | Cryptorchidism | Spondylo-ocular Syndrome | Choriocarcinoma | Osteogenesis Imperfecta Type I | Hypertensive Nephropathy | Congenital Dyserythropoietic Anemia | Gray Platelet Syndrome | Hypertension | Lattice Corneal Dystrophy | Scleritis | Retinitis | Antisynthetase Syndrome | Peyronie's Disease | Vascular Cognitive Impairment | Pain | Familial Thoracic Aortic Aneurysm | Zimmermann-Laband Syndrome | Spinocerebellar Ataxia Type 14 | Hypermethioninemia | Hereditary Spastic Paraplegia | Multiple Sclerosis, Secondary Progressive | CHARGE Syndrome | Otitis Media | Reflex Epilepsy | Dyggve-Melchior-Clausen Disease | DNA Ligase IV Deficiency | Saethre-Chotzen Syndrome | Cholestasis, Intrahepatic | Syndactyly | Proteus Syndrome | Hepatitis, Alcoholic | Pituitary Stalk Interruption Syndrome | Early Infantile Epileptic Encephalopathy 1 | Dementia | Multiple Sclerosis, Chronic Progressive | Neuroma | Thyroid Hormone Resistance | Lafora Disease | Megaloblastic Anemia | Meconium Ileus | Achondrogenesis | Optic Nerve Diseases | Ileitis | Hereditary Coproporphyria | Cardiac Arrest | Carcinoma, Small Cell | Ebstein Anomaly | Familial Advanced Sleep Phase Syndrome | Amelanotic Melanoma | Astigmatism | Avian Influenza | Pseudo-pseudohypoparathyroidism | Basal Ganglia Disease, Biotin-responsive | Giant Cell Arteritis | Farber Disease | Takenouchi-Kosaki Syndrome | Monilethrix | Sjogren Syndrome | Osteoporosis | Hyperbilirubinemia | Neurotoxicity | Hypoglycemia | GM2-gangliosidosis AB Variant | Leprosy | Thrombocythemia, Essential | Vitreoretinal Degeneration, Snowflake Type | Diabetic Macular Edema | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Primary Ovarian Insufficiency | Micro Syndrome | Optic Atrophy 2 | Nemaline Myopathy 10 | Coronary Restenosis | Dermatofibrosarcoma | Cutaneous Lupus Erythematosus | Cramp Fasciculation Syndrome | Hypoalbuminemia | Antiphospholipid Syndrome | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Thrombasthenia | Retinal Detachment