Gestational Trophoblastic Disease

About the Disease
Gestational Trophoblastic Neoplasm, also known as hydatidiform mole, is related to partial hydatidiform mole and placental site trophoblastic tumor. An important gene associated with Gestational Trophoblastic Neoplasm is NLRP7 (NLR Family Pyrin Domain Containing 7), and among its related pathways/superpathways are Peptide hormone metabolism and Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Amifostine and Nitroglycerin have been mentioned in the context of this disorder. Affiliated tissues include placenta, lung and t cells, and related phenotypes are endocrine/exocrine gland and reproductive system

Common Targets
DNA-Directed RNA Polymerase (nonspecified subtype)

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