Disease

Dyslipidemia

About the Disease
Lipid Metabolism Disorder, also known as dyslipidemia, is related to hyperlipoproteinemia, type iii and hypobetalipoproteinemia, familial, 1. An important gene associated with Lipid Metabolism Disorder is LIPC (Lipase C, Hepatic Type), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Tocopherol and Aripiprazole have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and bone marrow, and related phenotypes are no effect and no effect

Common Targets
ADORA1 | KEAP1 | IL10 | MIR541 | ANGPTL4 | FFAR1 | G367 | ADIPOQ | PDK1 | ZPR1 | DGAT1 | APLNR | TRPV2 | MOGAT2 | NPM1 | XDH | TMPRSS15 | ADORA2B | DHODH | TRIB1 | MIR33B | MIR33A | DSCAML1 | HSD11B1 | DPP4 | APOA5 | SCD | NPC1L1 | PTPN1 | ENG | Thyroid hormone receptor (nonspecified subtype) | NF-kappaB (NFkB) | UGCG | GCK | SLC6A4 | DGAT2 | PPARD | CES2 | ABCA1 | SLC22A12 | MAPK11 | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | MGAT2 | SLC12A4 | PDE9A | PCSK9 | OGFOD3 | ANGPTL3 | Serine palmitoyltransferase | PDK2 | UGT1A7 | PGAM5-KEAP1-NRF2 Complex | NR1H4 | S1PR2 | Cholesterol esterase (nonspecified subtype) | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | NMDA receptor | Oxysterols receptor LXR (nonspecified subtype) | NPY2R | APOC3 | Liver Bile Transporters (LBAT) (nonspecified subtype) | CES1 | RAMP2 | EIF4B | MMAB | GALNT2 | AGTR1 | GCKR | GIPR | TRPA1 | IFNG | IAPP | NOS2 | Casein kinase II (CKII) | IL2 | Amylin receptor | MIR379 | MVK | FASN | BAD | FASLG | FFAR2 | Histone deacetylase (nonspecified subtype) | P2RY13 | UGT2B7 | ANGPTL8 | Trypsin (nonspecified subtype) | NPY | SLC10A1 | LEPR | LIPC | CALCRL | ACVRL1 | FABP5 | HNF1A | IL4 | Pyruvate dehydrogenase kinase (nonspecified subtype) | CPB2 | CYP2C9 | STAT2 | UGT1A1 | Triacylglycerol Lipase (TG Lipase) (nonspecified subtype) | LMNA | PON1 | CYP19A1 | BTN2A1 | MTTP | HTR2C | SLCO1B1 | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | SLC5A1 | HCAR1 | FTO | SLC6A3 | GPR55 | GPIHBP1 | INSIG2 | GLP1R | APOA1 | RORB | ACACB | MAOB | SLC10A2 | AMP-activated protein kinase (AMPK) | ACE | ZC3H13 | ADIPOR2 | APOB | PLA2G2D | METAP2 | Phospholipase A2, Secretory (sPLA2) (nonspecified subtype) | IL18 | MSR1 | CRP | LIPE | G5243 | DAGLA | G4780 | IL23R | CNR2 | Sterol Regulatory Element-Binding Protein (nonspecified subtype) | HCAR2 | Fatty Acid Binding Protein (nonspecified subtype) | NR1D1 | Retinoid RXR receptor (nonspecified subtype) | ACLY | EPAS1 | CALCR | PPARG | PNLIP | HCAR3 | SOAT2 | PPARGC1A | ACACA | FAM3C | FABP4 | SLC30A8 | SIRT3 | Phosphodiesterase (nonspecified subtype) | DDAH2 | CYP3A4 | THRA | PPARA | HRH3 | SLCO1B3 | LIPG | NR3C1 | HTR7 | G7124 | 11beta-Hydroxysteroid Dehydrogenase (nonspecified subtype) | DOCK7 | IL12B | LDLR | Calcium channel (nonspecified subtype) | CYP2C19 | SPP1 | DAGLB | CAT | GCGR | APOC2 | CNR1 | MBOAT4 | SLC5A2 | GPBAR1 | TRPM8 | CLOCK | TRPV1 | G3569 | Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) | SLC6A2 | FADS1 | KCNJ11 | SIRT6 | PLA2G2A | CETP | ACHE | HTR1A | LCAT | G9429 | Acetyl-CoA Carboxylases (ACC) (nonspecified subtype) | BRD4 | G3630 | SREBF1 | FFAR4 | FGFR1 | CD36 | LPL | THRB | G23411 | HMGCR | Diacylglycerol Acyltransferase (DGAT) (nonspecified subtype) | G1432 | GPR119 | Estrogen receptor (nonspecified subtype) | PASK

疾病靶点研报
Dyslipidemia

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