Frontometaphyseal Dysplasia

About the Disease
Frontometaphyseal Dysplasia, also known as fmd, is related to frontometaphyseal dysplasia 2 and frontometaphyseal dysplasia 1. An important gene associated with Frontometaphyseal Dysplasia is FLNA (Filamin A), and among its related pathways/superpathways are TNF Superfamily - Human Ligand-Receptor Interactions and their Associated Functions and Cytoskeletal Signaling. Affiliated tissues include bone, heart and spinal cord, and related phenotypes are scoliosis and skeletal dysplasia

Common Targets
FLNA | MAP3K7

Note: If you'd like to get a target analysis report for Frontometaphyseal Dysplasia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Frontometaphyseal Dysplasia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Anovulation | Acrodermatitis | Panuveitis | Hypotension, Orthostatic | Ureteropelvic Junction Obstruction | Enterocolitis, Necrotizing | Dermatitis | McKusick Type Metaphyseal Chondrodysplasia | Kaposi Sarcoma | Auriculocondylar Syndrome | Schwannoma | Polycystic Kidney, Autosomal Dominant | Antisocial Personality Disorder | Familial Episodic Pain Syndrome | Craniofacial Dysostosis | Oral Lichen Planus | Sepiapterin Reductase Deficiency | Epithelial-myoepithelial Carcinoma | Astrocytoma, Anaplastic | Peripheral T-cell Lymphoma | Multiple Sclerosis | Hypospadias | Persistent Fetal Circulation | Vitamin B12 Deficiency | Pelvic Inflammatory Disease | Hyperparathyroidism, Secondary | Arthritis, Psoriatic | Branchiootorenal Syndrome | Pityriasis Rubra Pilaris | Language Disorders | Hydrocephalus | Cholera | Congenital Myasthenic Syndrome | Melanocytic Nevus | Incontinentia Pigmenti | Astrocytoma | Polyarteritis Nodosa | Syndactyly | Apparent Mineralocorticoid Excess Syndrome | Anemia | Giant Cell Glioblastoma | Nijmegen Breakage Syndrome | X-linked Creatine Transporter Deficiency | Kashin-Beck Disease | Hemorrhoids | Stiff-man Syndrome | Spinocerebellar Ataxia Type 12 | Delirium | Insulin Resistance | Wolfram Syndrome 2 | Wieacker-Wolff Syndrome | Pituitary Dwarfism | GLUT1 Deficiency Syndrome | Diabetic Nephropathy | Keratocystic Odontogenic Tumor | Scapuloperoneal Spinal Muscular Atrophy | Glucagonoma | Dysplastic Nevus | Agnathia-Otocephaly Complex | Subcortical Band Heterotopia | Endometritis | Stroke, Hemorrhagic | Myasthenia Gravis | Hypereosinophilic Syndrome | Cholangiocarcinoma | Corneal Ulcer | Ellis-Van Creveld Syndrome | Spinal Muscular Atrophy | C3 Glomerulonephritis | Leiomyoma | Schnyder Crystalline Corneal Dystrophy | Disseminated Intravascular Coagulation | Hermansky-Pudlak Syndrome | Familial Hemiplegic Migraine | Hemorrhagic Disorders | Hydrolethalus Syndrome | Omenn Syndrome | Waardenburg Syndrome Type 2E | Congenital Dysfibrinogenemia | Paget's Disease Of The Breast | Myocardial Infarction | Christianson Syndrome | Cluster Headache | Gyrate Atrophy Of The Choroid And Retina | Birt-Hogg-Dube Syndrome | Non-Hodgkin Lymphoma | Fetal Alcohol Syndrome | Intracerebral Hemorrhage | Silver-Russell Syndrome | Depression | Hyperthyroidism | Transcobalamin Deficiency | Aarskog-Scott Syndrome | Esophageal Carcinoma | Goldenhar Syndrome | Optic Atrophy 2 | Guttate Psoriasis | Spondylocarpotarsal Synostosis Syndrome | Congenital Heart Defects | Acne | Amyotrophic Lateral Sclerosis, Juvenile | Gout | Pseudomyxoma Peritonei | Skin Carcinoma | Prolidase Deficiency | Glycogen Storage Disease Type 1 | Okihiro Syndrome | Cartilage Disorders | Hypertrophy | Schnitzler Syndrome | Nicolaides-Baraitser Syndrome | Neonatal Progeroid Syndrome | Chorea | Norrie Disease | Rothmund-Thomson Syndrome | Fowler's Syndrome | Urolithiasis | Hernia, Inguinal | Robinow Syndrome | Odonto-onycho-dermal Dysplasia | Fuchs Heterochromic Iridocyclitis | Cornelia De Lange Syndrome | Vasculitis | Cole-Carpenter Syndrome | Hypoglycemia | Spinocerebellar Ataxia Type 14 | Tumoral Calcinosis | Charcot-Marie-Tooth Disease, Type 1A | Sulfite Oxidase Deficiency | Syphilis | Gerodermia Osteodysplastica | Sarcoidosis | Glioblastoma | Acrodermatitis Enteropathica | Kaposiform Hemangioendothelioma | Familial Isolated Hyperparathyroidism | Glomerulonephritis | Gastroenteritis, Eosinophilic | Hyperparathyroidism | Cutaneous Mastocytosis | Frontometaphyseal Dysplasia | Opisthorchiasis | Spasticity | Rash | Weill-Marchesani Syndrome | Thyroiditis, Autoimmune | Blue Nevus | Carcinoma, Squamous Cell | Ichthyosis | Best Macular Dystrophy | Pulmonary Veno-occlusive Disease | Pre-eclampsia | Osteoporosis-pseudoglioma Syndrome | Encephalopathy, Hepatic | Asthma, Nocturnal | Sturge-Weber Syndrome | Progressive Myoclonic Epilepsy | Osteopetrosis | Periodontitis | Bietti Crystalline Dystrophy | Schaaf-Yang Syndrome | Hypoalbuminemia | Paroxysmal Kinesigenic Dyskinesia | Familial Male-limited Precocious Puberty | Gastritis | Glycogen Storage Disease Type 0, Muscle | Chronic Thromboembolic Pulmonary Hypertension | N-acetylglutamate Synthase Deficiency | Polycystic Kidney, Autosomal Recessive | Familial Exudative Vitreoretinopathy | Corneal Edema | Heavy Chain Disease | Chondrodysplasia Punctata | Alstrom Syndrome | Cardiofaciocutaneous Syndrome | Cavitary Optic Disc Anomalies | Liver Diseases | Peters-plus Syndrome | Seizures | Xeroderma Pigmentosum | Mycosis Fungoides | MELAS Syndrome | Dermatomyositis | Cerebellar Ataxia, Cayman Type | Adenocarcinoma | Carpal Tunnel Syndrome | Pyelonephritis | Niemann-Pick Disease, Type A | Paraganglioma, Carotid Body | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Keratoconus | Sleep Disorder | Veno-occlusive Disease | Shock, Cardiogenic | Acromegaly | Heart Failure | Thyroid Dyshormonogenesis | Blastomycosis | Hoyeraal-Hreidarsson Syndrome | Dyslexia | Usher Syndrome Type I | Chordoid Glioma | Thyroid Dysgenesis | Cold-induced Sweating Syndrome | Inborn Errors Of Metabolism | Sarcoma, Ewing | Relapsing Polychondritis | Osteomalacia | Cabezas Syndrome | Long QT Syndrome Type 2 | Mountain Sickness | Early Infantile Epileptic Encephalopathy | Skin Papilloma | Tremor | Hemolytic Uremic Syndrome, Atypical | Pterygium | Johanson-Blizzard Syndrome | Thrombocytopenia | DEND Syndrome | Tardive Dyskinesia | Kawasaki Disease | Hepatitis, Chronic | Crimean-Congo Hemorrhagic Fever | HELLP Syndrome | DiGeorge Syndrome | Charcot-Marie-Tooth Disease Type 4D | Senior-Loken Syndrome | Sick Sinus Syndrome | Myhre Syndrome | Currarino Syndrome | Stroke | Osteochondroma | Canavan Disease | Reflex Epilepsy | Mitochondrial Disease | Kohlschutter-Tonz Syndrome | Pulmonary Sclerosing Hemangioma | Behcet's Disease | Asthma, Exercise-induced | Alcoholism | Long QT Syndrome Type 3 | Androgen Insensitivity | Hypertension, Renovascular | Carney Triad | Panniculitis | Silicosis | Pseudoachondroplasia | Spinocerebellar Ataxia Type 10 | Cantu Syndrome | Craniofrontonasal Syndrome | Neurofibromatosis | Temporal Lobe Epilepsy | GNE Myopathy | Schizophrenia | Meningitis | Hypoparathyroidism | Succinic Semialdehyde Dehydrogenase Deficiency | Neural Tube Defect | Optic Neuritis | Persistent Mullerian Duct Syndrome | Lymphedema | Pontocerebellar Hypoplasia Type 2 | Varices | Chronic Leukemia | Acute Motor Axonal Neuropathy | Seborrheic Dermatitis | Stomatitis | Asthma | Hemimegalencephaly | Sweet Syndrome | Essential Fructosuria | Encephalopathy, Glycine | Tendinopathy | Neurodermatitis | Coloboma | Spondylo-ocular Syndrome | Lipid Metabolism Disorders | Spinal Muscular Atrophy Type 2 | Scleroderma | Basal Ganglia Cerebrovascular Disease | Hemophilia | Bruck Syndrome | Polyneuropathy | Ileitis | Viral Meningitis | CEDNIK Syndrome | Fragile X Syndrome | KBG Syndrome | Lamellar Ichthyosis | Greenberg Dysplasia | Carpenter Syndrome | Spinal Cord Diseases | Gaucher Disease | Diabetes | Split Hand-foot Malformation | Syncope | Histoplasmosis | Porphyria Cutanea Tarda | Herpes Genitalis | Hypotonia-cystinuria Syndrome | MIRAGE Syndrome | Meier-Gorlin Syndrome | Pyloric Stenosis, Infantile Hypertrophic | Myopia | Benign Hereditary Chorea | Colitis, Microscopic | Hemoglobinopathies | Adenomyosis | Hyperinsulinemic Hypoglycemia | Paronychia | Hepatoblastoma | Mast Cell Leukemia | Chronic Idiopathic Myelofibrosis | Hypertensive Retinopathy | Cirrhosis | Erythema Nodosum | Shprintzen-Goldberg Syndrome | Sarcosinemia | Schizoaffective Disorder | 3-methylglutaconic Aciduria | Nutrition Disorders | Polymyositis | Waardenburg Syndrome | DRESS Syndrome | Glycogen Storage Disease | Ghosal Syndrome | Cyclic Vomiting Syndrome | Hepatitis C, Chronic | Strabismus | WAGR Syndrome | Congenital Dyserythropoietic Anemia Type 4 | Pernicious Anemia | Anodontia | Endometriosis | Congenital Tufting Enteropathy | Protein C Deficiency | Neuromyelitis Optica | Familial Advanced Sleep Phase Syndrome | Hyperandrogenemia | Loeys-Dietz Syndrome | Agammaglobulinemia | Encephalitis, Tick-borne | Psoriasis | Papillon-Lefevre Syndrome | Pilomatrix Carcinoma | Hyper IgE Syndrome | Ganglioglioma | Retinal Dystrophy | Osteogenesis Imperfecta Type III | Malnutrition | T-cell Chronic Lymphocytic Leukemia | VACTERL/VATER Association | Epithelioid Hemangioma | Familial Partial Lipodystrophy | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Exostoses | Mitochondrial Myopathy | Myositis, Focal | Fibromyalgia | Raynaud Phenomenon | Acute Coronary Syndrome | Joubert Syndrome 2 | Keratopathy | Thrombotic Microangiopathy | Alazami Syndrome | Malaria, Cerebral | Primary Carnitine Deficiency | VACTERL Association | Campomelic Dysplasia | Measles | Venous Insufficiency | Cervical Dystonia | Ichthyosis Hystrix, Curth-Macklin Type | Conn Syndrome | HIBCH Deficiency | Dermatitis Herpetiformis | Arthritis | Pyoderma Gangrenosum | Scapuloperoneal Myopathy, X-linked Dominant | Nevus | Primary Progressive Aphasia | Ectrodactyly | Chronic Mucocutaneous Candidiasis | Epidermolysis Bullosa Simplex, Localized | Olmsted Syndrome | Retinal Dystrophy, Early-onset Severe | Ichthyosis, X-linked | Astigmatism | Leri Pleonosteosis | Congenital Stromal Corneal Dystrophy | Leprosy | Peripheral Neuropathy | Intestinal Obstruction | Charcot-Marie-Tooth Disease Type 4B1 | Twin-to-twin Transfusion Syndrome | Colorectal Adenoma | Cancer, Prostate | LMNA-related Congenital Muscular Dystrophy | Menkes Disease | Cancer, Breast