Disease

Atypical Hemolytic Uremic Syndrome

About the Disease
Hemolytic Uremic Syndrome, Atypical 1, also known as atypical hemolytic-uremic syndrome, is related to genetic atypical hemolytic-uremic syndrome and d-minus hemolytic uremic syndrome. An important gene associated with Hemolytic Uremic Syndrome, Atypical 1 is CFH (Complement Factor H), and among its related pathways/superpathways are Innate Immune System and Diseases of hemostasis. The drugs Hematinics and Epoetin Alfa have been mentioned in the context of this disorder. Affiliated tissues include kidney, skin and heart, and related phenotypes are proteinuria and thrombocytopenia

Common Targets
CFB | VWF | C1S | CFI | ADAMTS13 | C5 | CFD | C8B | CFHR1 | MMACHC | CAPG | PHB1 | PCSK9 | MASP2 | CFHR5 | CFHR4 | CFHR3 | C3AR1 | PLG | MTHFR | TRPC6 | DGKE | FCN1 | CR1 | FKRP | Complement Complex | C3 | C5AR1 | MASP1 | CFH | C9 | TFB1M | CD46 | THBD | C2 | F12 | CR2 | SMARCAL1 | C8A | CD36

疾病靶点研报
Atypical Hemolytic Uremic Syndrome

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