Binge Eating Disorder

About the Disease
Bulimia Nervosa, also known as bulimia, is related to abdominal obesity-metabolic syndrome 1 and polysubstance abuse, and has symptoms including salt craving, symptoms and decrease in appetite. An important gene associated with Bulimia Nervosa is BULN (Bulimia Nervosa, Susceptibility To), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Memantine and Sibutramine have been mentioned in the context of this disorder. Affiliated tissues include thyroid, prefrontal cortex and skin, and related phenotypes are bulimia and nervous system

Common Targets
Carbonic Anhydrase (nonspecified subtype) | BDNF | GPR139 | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | G7099 | CACNA2D1 | OPRK1 | GHSR | Kainate Receptor (GluR) (nonspecified subtype) | OPRM1 | Metabotropic glutamate (mGluR) receptor (nonspecified subtype) | Gamma-Aminobutyric acid type B receptor | DRD2 | SIGMAR1 | Alpha-2 Adrenergic receptors (nonspecified subtype) | T-Type Calcium Channel | HTR1A | CRH | SLC6A2 | ANKK1 | HCRTR1 | LINC00880 | Glutamate Transporter (nonspecified subtype) | SLC44A3-AS1 | LINC01260 | FLNA | Voltage-Gated Sodium Channel Complex | OXT | ARHGAP8 | OPRD1 | PRR5-ARHGAP8 | NPY5R | Sodium channel (nonspecified subtype) | HCRTR2 | BDNF-AS | FASN | SLC6A4 | ANG | CRHR1 | NMDA receptor | CA2 | RNASE4 | HTR2A | SLC5A1 | HTR1B | DAGLA | alpha1-Adrenoceptor (nonspecified subtype) | FTO | 5-Hydroxytryptamine Receptor (nonspecified subtype) | PNLIP | DRD3 | ANK2 | PNOC | GLP1R | SLC6A3 | OXTR | TAAR1 | CLOCK | HTR1D | HTR7 | ENPP2 | Glutamate Receptor Ionotropic AMPA Receptor | NRXN3 | LIPF

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