KBG Syndrome

About the Disease
Kbg Syndrome, also known as macrodontia, mental retardation, characteristic facies, short stature, and skeletal anomalies, is related to hypertelorism and 16q24.3 microdeletion syndrome. An important gene associated with Kbg Syndrome is ANKRD11 (Ankyrin Repeat Domain Containing 11), and among its related pathways/superpathways are Chromatin Regulation / Acetylation and 22q11.2 copy number variation syndrome. Affiliated tissues include bone, heart and kidney, and related phenotypes are scoliosis and short neck

Common Targets
AP4B1 | ACADS | SETD5 | ANKRD11 | SMARCB1 | MED12

Note: If you'd like to get a target analysis report for KBG Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of KBG Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

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Persistent Truncus Arteriosus | Gangliosidosis | Hereditary Elliptocytosis | Spinocerebellar Ataxia Type 5 | Atopic Dermatitis | Hemophagocytic Lymphohistiocytosis | Encephalocele | Nanophthalmos | Frontometaphyseal Dysplasia | Congenital Myopathy | Greig Cephalopolysyndactyly Syndrome | Varicocele | DRESS Syndrome | Jacobsen Syndrome | Aneurysm, Thoracic Aortic | Urolithiasis | Waardenburg Syndrome Type 4A | Whipple's Disease | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Infertility | Niemann-Pick Disease | Early Infantile Epileptic Encephalopathy 4 | Leukemia-lymphoma, Adult T-cell | Hartnup Disease | Methemoglobinemia | Homocystinuria | GLUT1 Deficiency Syndrome | Lymphangiomatosis | Neurofibroma | Ornithine Transcarbamylase Deficiency | Multiple Myeloma | Hypotonia-cystinuria Syndrome | Corneal Dystrophy And Perceptive Deafness | Dent Disease | Epicondylitis | Glaucomatocyclitic Crisis | Malnutrition | Muscle Wasting | Apert Syndrome | Dysfibrinogenemia | Neurotoxicity | Muscular Dystrophy | Cancer, Colon | Cancer, Brain | Carcinoid Tumor | Onchocerciasis | Schizoaffective Disorder | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Noonan Syndrome | Fuchs Heterochromic Iridocyclitis | Neurofibromatosis Type 2 | Corticobasal Syndrome | Orotic Aciduria | Zellweger Syndrome | Cervicitis | Multiple Sclerosis, Primary Progressive | Heart Failure | Glioblastoma Multiforme | Ocular Hypertension | Cole-Carpenter Syndrome | Metatropic Dysplasia | Hemorrhoids | Aneurysm, Abdominal Aortic | Hypervalinemia | Multisystemic Smooth Muscle Dysfunction Syndrome | Papillon-Lefevre Syndrome | Alveolar Capillary Dysplasia | Autosomal Recessive Congenital Ichthyosis | Myasthenia Gravis | Inflammatory Bowel Disease | Galactosemia | Neurofibromatosis | Portal Vein Thrombosis | Multicentric Carpotarsal Osteolysis Syndrome | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Holt-Oram Syndrome | Lymphopenia | Primary Aldosteronism | Myoclonus-dystonia Syndrome | Uveitis | Myelofibrosis | Aplasia Cutis Congenita | Giant Cell Glioblastoma | Hypertensive Retinopathy | Retinal Diseases | Phosphoglycerate Dehydrogenase Deficiency | Leukoplakia | Thrombocythemia, Essential | Glanzmann Thrombasthenia | Proctitis | Autonomic Neuropathy | Glioma | Familial Glucocorticoid Deficiency | Torticollis | Cone Dystrophy | Benign Familial Neonatal Convulsions | Stromal Corneal Dystrophy | Multiple System Atrophy | Gastritis, Atrophic | Patent Foramen Ovale | Epidermolytic Ichthyosis, Annular | High Molecular Weight Kininogen Deficiency | Sarcoma | Wilson's Disease | Carcinoma, Transitional Cell | Oligoasthenoteratozoospermia | Vici Syndrome | Agranulocytosis | Japanese Encephalitis | Hemangioblastoma | Thrombocytopenia | Gestational Trophoblastic Disease | Proopiomelanocortin Deficiency | Bronchitis, Chronic | Spinal Cord Diseases | Coffin-Lowry Syndrome | Narcolepsy | Restless Legs Syndrome | Spondylo-ocular Syndrome | Cholangitis | Adenosine Deaminase 2 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