Bruck Syndrome

About the Disease
Bruck Syndrome, also known as osteogenesis imperfecta-congenital joint contractures syndrome, is related to scoliosis and distal arthrogryposis. An important gene associated with Bruck Syndrome is FKBP10 (FKBP Prolyl Isomerase 10), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. Affiliated tissues include bone and bone marrow, and related phenotypes are joint stiffness and short stature

Common Targets
PLOD2 | FKBP10 | TRNL1

Note: If you'd like to get a target analysis report for Bruck Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Bruck Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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