Neuropathy

About the Disease
Neuropathy, also known as peripheral neuropathy, is related to neuropathy, hereditary, with liability to pressure palsies and neuropathy, hereditary sensory and autonomic, type iia, and has symptoms including back pain, headache and neuralgia. An important gene associated with Neuropathy is DLX6-AS1 (DLX6 Antisense RNA 1), and among its related pathways/superpathways are Neural crest differentiation and EGR2 and SOX10-mediated initiation of Schwann cell myelination. The drugs Capsaicin and Mexiletine have been mentioned in the context of this disorder. Affiliated tissues include nerves, dorsal root ganglion and bone marrow, and related phenotypes are no effect and no effect

Common Targets
IL1B | G23411 | TARDBP | GARS1 | SLC28A3 | LOC100506071 | G3845 | FDXR | AARS1 | TRPV4 | SPTLC2 | ORAI1 | SFN | IL10 | FKBP4 | PMP22 | IL4R | MDK | SLC28A1 | RRM1 | WARS1 | NTRK1 | ABCC5 | HRH2 | Calcium release-activated channel (CRAC) | UBA5 | TSFM | GCK | Neurotrophic Factor (nonspecified subtype) | SLC22A12 | AKR1B1 | DDX39B | GSK3B | ABCC2 | SOD2 | NTRK3 | SLC6A4 | STOML3 | MPZ | SSTR3 | ERCC2 | ATP7A | Gap junction Connexin ( (nonspecified subtype) | CYP2C8 | IL-4 receptor | FAT3 | G4137 | PRX | NMDA receptor | SEPTIN9 | BICD2 | PDK3 | SLC19A1 | ANK1 | GSTP1 | RARB | GM1 ganglioside | KCNS1 | LOC100287329 | AGTR1 | SBF2 | CA7 | USP14 | TRPA1 | CYP3A5 | MME | POLG | IL1A | HARS1 | SCN11A | G472 | CCND3 | NDRG1 | IGHMBP2 | CA13 | SSTR4 | BSCL2 | SCN9A | TK2 | KIF5A | CHAF1A | LRSAM1 | GSTM1 | ROCK2 | HRH1 | mTOR complex 2 | SPIDR | NDUFAF6 | HSPB8 | KLC3 | HINT1 | WNK1 | MFN2 | APOE | IL4 | TYMS | CA2 | sigma Receptor (nonspecified subtype) | HMBS | ACTG2 | APEX1 | FPR2 | Potassium Channels (nonspecified subtype) | PARP2 | POLR1G | HSPB1 | EPOR | NMNAT2 | HK1 | OGA | SCN5A | SYT2 | AGTR2 | VCP | XRCC1 | SBF1 | DNAJB2 | SAMHD1 | SLC12A6 | DHFR | MARS1 | CDK6/Cyclin D3 | EPHA5 | HK2 | KRR1 | SLC5A7 | CYP11B2 | LOC105374608 | CYP4F2 | OPRM1 | G2475 | RIPK1 | Gap Junction Protein (nonspecified subtype) | VRK1 | HIF1A | IL18 | HDAC6 | CA14 | OTOF | G4780 | COCH | MTHFR | FIG4 | MYH7 | G5243 | NTRK2 | CA5B | ATL3 | FGD2 | CEP72-DT | GDAP1 | IL-13 receptor | KIF1A | Glutamate Receptor Ionotropic AMPA Receptor | AGXT | CYP3A4 | NEFL | ALDOB | CDK4 | NGF | SLCO1B3 | ADRA2C | IL12B | CEP72 | SLC31A1 | INF2 | SCN10A | Heat shock protein 90 (nonspecified subtype) | TUBB2A | TRPM3 | GJB1 | DCLRE1A | CDK4/Cyclin D3 | G142 | ERCC1 | G5743 | XPC | RRM2B | G7124 | SSTR2 | GJB2 | SLC6A2 | PRPS1 | MFN1 | C5 | EPHA6 | G9429 | HTR1A | Alpha-2 Adrenergic receptors (nonspecified subtype) | TTR | TFG | TUBB | CAPN10 | AIFM1 | FANCD2 | SH3TC2 | Kainate Receptor (GluR) (nonspecified subtype) | Voltage-Gated Sodium Channel Complex | KCNN3 | Sodium channel (nonspecified subtype) | MAP3K12 | LTA

Note: If you'd like to get a target analysis report for Neuropathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Neuropathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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