T-cell Prolymphocytic Leukemia

About the Disease
T-Cell Prolymphocytic Leukemia, also known as t cell prolymphocytic leukemia, is related to prolymphocytic leukemia and ataxia-telangiectasia. An important gene associated with T-Cell Prolymphocytic Leukemia is ATM (ATM Serine/Threonine Kinase), and among its related pathways/superpathways are Akt Signaling and TCR Signaling (Qiagen). The drugs Fludarabine and Mycophenolic acid have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, spleen and liver.

Common Targets
HDAC6 | HDAC2 | DTX2 | G598 | HDAC3 | NOTCH4 | HDAC1 | CD7 | MAML2 | G4193 | MAML1 | KDM6B | NOTCH2 | CD37 | G596 | STAT5B

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