Heroin Dependence

About the Disease
Heroin Dependence is related to acute stress disorder and morphine dependence. An important gene associated with Heroin Dependence is MEG3 (Maternally Expressed 3), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Diamorphine and Methadone have been mentioned in the context of this disorder. Affiliated tissues include prefrontal cortex, brain and cortex, and related phenotypes are nervous system and homeostasis/metabolism

Common Targets
CHRM4 | DRD4 | GLRA1 | GABRG2 | TTC12 | GRIN2C | NCAM1 | GABRB2 | NPY1R | GAL | IPCEF1 | ANKK1 | POMC | DBH | SLC6A4 | HTR2A | OPRD1 | FAT3 | GRIN2A | NMDA receptor | ADH1B | KTN1 | CHRNA2 | CRHBP | FAAH | DLG2 | FKBP5 | GABRB3 | LOC101929309 | CAMK2A | HCRTR2 | ZNF804A | BDNF-AS | LINC02210-CRHR1 | CRHR1 | HTR1B | ENO2 | ANKS1B | HTR3B | TH | DRD3 | SLC6A3 | GRM3 | GRM1 | CHRM5 | KCNJ6 | CYP2B6 | GABRD | OPRM1 | LOC105378589 | GABRA2 | GRIN2B | CHRNA4 | GAD1 | CHRM2 | G5243 | PPARG | DRD2 | BDNF | CRHR2 | OPRK1 | GABRA6 | DCC | GRIN3A | AVPR1A | AUTS2 | NR3C1 | NR3C2 | DLGAP2 | MIR4761 | COMT | CLOCK | CHRNA5 | CNR1 | GRIN3B | AGBL4 | SLC6A2 | CSNK1E | LIN7C | CHRNA10 | PDYN | G3630 | ALDH2 | CT66 | AVP

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