Disease

Angioedema

About the Disease
Angioedema, also known as angioneurotic oedema, is related to acquired angioedema and angioedema, hereditary, 3, and has symptoms including edema and peau d'orange. An important gene associated with Angioedema is F12 (Coagulation Factor XII), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Complement cascade. The drugs Omalizumab and Lactitol have been mentioned in the context of this disorder. Affiliated tissues include skin, tongue and brain, and related phenotypes are homeostasis/metabolism and renal/urinary system

Common Targets
BDKRB2 | PLA2G4A | ETV6 | SYK | TIE1 | DENND1B | MME | SPNS1 | TNFRSF11A | PLCG1 | Kallikrein (nonspecified subtype) | F5 | KCNMA1 | APP | CYSLTR2 | PRKCQ | F11 | CRB1 | LAT | KLKB1 | F7 | F12 | Complement component 1q

疾病靶点研报
Angioedema

Note: If you'd like to get a target analysis report for Angioedema, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Angioedema at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Anosmia, Congenital | Rhabdomyosarcoma, Alveolar | Alagille Syndrome | Panniculitis | Pemphigus | Uremic Pruritus | Bone Giant Cell Tumor | Seborrheic Dermatitis | Congenital Primary Aphakia | Christianson Syndrome | Hereditary Hemorrhagic Telangiectasia | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Familial Thoracic Aortic Aneurysm | Gigantism | Intestinal Pseudo-obstruction | Schizophrenia, Paranoid | Acute Motor Axonal Neuropathy | Monilethrix | GLUT1 Deficiency Syndrome | Keratopathy | Glycogen Storage Disease Type 9 | Stroke, Ischemic | Tetraplegia | Cancer, Breast | Omenn Syndrome | Pituitary Stalk Interruption Syndrome | Hypermethioninemia | Choroideremia | Idiopathic Multicentric Castleman Disease | Cutaneous T-cell Lymphoma | Niemann-Pick Disease, Type B | Epilepsy, Generalized | Hidradenitis | Glycogen Storage Disease Type 4 | Hepatitis, Chronic | Nephrocalcinosis | Urethritis | Hepatitis | Muscular Dystrophy | Disseminated Intravascular Coagulation | Spinocerebellar Ataxia Type 27 | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Non-Hodgkin Lymphoma | Combined Pituitary Hormone Deficiency | Becker Muscular Dystrophy | Hyperostosis | Dermatofibrosarcoma | Menetrier Disease | Li-Fraumeni Syndrome | Fibrosarcoma | WAGR Syndrome | Achondrogenesis | Larsen Syndrome | Supravalvular Aortic Stenosis | Krabbe Disease | Patent Ductus Arteriosus | Ataxia-ocular Apraxia 2 | Tumoral Calcinosis | Proopiomelanocortin Deficiency | Hypogonadism | Agammaglobulinemia | Diverticulitis | Purpura, Thrombotic Thrombocytopenic | Reticular Dysgenesis | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Glutaric Aciduria Type 2 | Antithrombin III Deficiency | Schizotypal Personality Disorder | Azoospermia | Mitochondrial Disease | Limb Girdle Muscular Dystrophy | Hypoplastic Left Heart Syndrome | Aspergillosis | Eosinophilia | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Hepatopulmonary Syndrome | C3 Glomerulonephritis | Oguchi Disease-2 | Autism | Echinococcosis | Astrocytoma, Anaplastic | Tardive Dyskinesia | Neuroma | Guttate Psoriasis | Pleomorphic Xanthoastrocytoma | Hypercholesterolemia, Familial | Hyperbilirubinemia | Fibrodysplasia Ossificans Progressiva | Myelodysplasia | Non-bullous Congenital Ichthyosiform Erythroderma | Myopia | Atelosteogenesis Type 1 | Focal Dermal Hypoplasia | Heart Septal Defects | Currarino Syndrome | Congenital Nephrotic Syndrome | Fraser Syndrome | Mountain Sickness | Nephrosclerosis | Olmsted Syndrome | Cranioectodermal Dysplasia | Tay-Sachs Disease | Carbonic Anhydrase VA Deficiency | DRESS Syndrome | Anorchia | Demyelinating Diseases | Microcephaly, Seizures, And Developmental Delay | Primary Hyperoxaluria Type 3 | Creatine Deficiency Syndrome | Glycogen Storage Disease Type 5 | Alexander Disease | Wolfram Syndrome 2 | Inflammatory Myofibroblastic Tumor | Hepatic Steatosis | POEMS Syndrome | Thyrotoxic Periodic Paralysis | Nemaline Myopathy | Angiodysplasia | Nanophthalmos | Hypercholesterolemia | 3-methylglutaconic Aciduria Type IV | Diamond-Blackfan Anemia | Coffin-Lowry Syndrome | CHOPS Syndrome | Erythema Nodosum | Peeling Skin Syndrome Type B | Congenital Myasthenic Syndrome | Colitis | Polyarteritis Nodosa | Keratoacanthoma | Brachydactyly | Chronic Myelomonocytic Leukemia | Greenberg Dysplasia | Gangliosidosis | McKusick Type Metaphyseal Chondrodysplasia | Tic Disorder | Renal Tubular Acidosis | Adult Polyglucosan Body Disease | Chronic Periodontitis | Cocaine-Related Disorders | T-cell Chronic Lymphocytic Leukemia | Richter's Syndrome | X-linked Acrogigantism | Multiple Hamartoma Syndrome | Stevens-Johnson Syndrome | T-cell Lymphoma, Subcutaneous Panniculitis-like | Hypoparathyroidism | Dementia, Vascular | Progressive Myoclonic Epilepsy | Arthritis, Gouty | Von Hippel-Lindau Disease | Primary Biliary Cholangitis | Non-small Cell Lung Cancer | Leukodystrophies | Waardenburg Syndrome Type 1 | Cramp Fasciculation Syndrome | Filariasis | Diabetes Type 1 | Nager Acrofacial Dysostosis | Yellow Fever | Acute Chest Syndrome | Waldenstrom Macroglobulinemia | Osteogenesis Imperfecta Type V | Cyclic Vomiting Syndrome | Trichorhinophalangeal Syndrome | Polyomavirus Nephropathy | Colitis, Lymphocytic | Cardiomyopathy, Hypertrophic | Glycogen Storage Disease Type 0, Muscle | Wiedemann-Steiner Syndrome | DICER1 Syndrome | Gliosarcoma | Episodic Ataxia Type 1 | Alpha-thalassemia Myelodysplasia Syndrome | Low Tension Glaucoma | Anuria | Corticobasal Syndrome | Acute Lung Injury | Hypertensive Retinopathy | Blastoma, Pleuropulmonary | IgA Nephropathy | Homocystinuria | Posterior Polar Cataract | Autosomal Recessive Spastic Paraplegia Type 75 | Cholesteryl Ester Storage Disease | IgA Deficiency | Hyperbilirubinemia, Neonatal | Central Retinal Artery Occlusion | T-cell Prolymphocytic Leukemia | Carney-Stratakis Syndrome | Nutrition Disorders | Gerstmann-Straussler-Scheinker Syndrome | Pierson Syndrome | Carcinoma, Merkel Cell | Cataract | Japanese Encephalitis | Histiocytosis | Klippel-Feil Syndrome | Tietze Syndrome | Juvenile Polyposis | Transient Bullous Dermolysis Of The Newborn | Neurofibromatosis Type 1 | Aldosteronism | Dysequilibrium Syndrome | Osteosclerosis | Hypoglycemia | Pigment Dispersion Syndrome | Primary Cutaneous Amyloidosis | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | H Syndrome | Palsy, Cerebral | Pulmonary Tuberculosis | Low Phospholipid Associated Cholelithiasis | Birk-Barel Syndrome | Primary Hyperoxaluria Type 1 | Encephalitis | Tinea Versicolor | Dystonia | Hypersensitivity | Leiomyosarcoma | Hypogammaglobulinemia | Holt-Oram Syndrome | Hereditary Sensory And Autonomic Neuropathy | Scoliosis | Paracoccidioidomycosis | Still Disease | Branchiootorenal Syndrome | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Familial Isolated Hyperparathyroidism | Nemaline Myopathy 10 | Stiff-man Syndrome | Calcium Pyrophosphate Deposition Disease | Double Outlet Right Ventricle | Myoclonic Epilepsy With Ragged Red Fibers | Alazami Syndrome | Adrenomyeloneuropathy | Familial Advanced Sleep Phase Syndrome | Familial Episodic Pain Syndrome | Oligodendroglioma | Generalized Epilepsy With Febrile Seizures Plus | Leri-Weill Dyschondrosteosis | X-linked Myotubular Myopathy | Diabetes Mellitus, Transient Neonatal | Osteogenesis Imperfecta | Cerebral Amyloid Angiopathy | Mitochondrial DNA Depletion Syndrome | Atrial Septal Defect | Schamberg Disease | Fabry's Disease | Xeroderma Pigmentosum Variant Type | Autoimmune Autonomic Ganglionopathy | Endometrial Hyperplasia | VEXAS Syndrome | Cabezas Syndrome | PASLI Disease | Hereditary Neuropathy With Liability To Pressure Palsies | Adenomatoid Tumor | Leber Congenital Amaurosis | Giant Cell Glioblastoma | Plasma Cell Dyscrasia | Epidermolysis Bullosa Simplex, Localized | Intracerebral Hemorrhage | Hyperkalemic Periodic Paralysis | Vitamin A Deficiency | DNA Ligase IV Deficiency | Lipid Storage Diseases | Congenital Torticollis | Pseudohermaphroditism | Phenylketonuria | Ghosal Syndrome | Anti-NMDA Receptor Encephalitis | Cold Agglutinin Disease | Contact Dermatitis | Trachoma | Myasthenia | Papulopustular Rosacea | Ebstein Anomaly | Influenza | Benign Familial Neonatal Convulsions | Maple Syrup Urine Disease | Gastric Atrophy | Acromesomelic Dysplasia | Myositis | Zimmermann-Laband Syndrome | Robinow Syndrome | Torticollis | 5-oxoprolinase Deficiency | Creutzfeldt-Jakob Disease | Histoplasmosis | Tangier Disease | Antisocial Personality Disorder | Neurofibroma, Plexiform | Cervicitis | Hemosiderosis | Glycogen Storage Disease | Chanarin-Dorfman Syndrome | Liddle Syndrome | Vitreoretinopathy, Proliferative | T-cell Leukemia | Cantu Syndrome | Methemoglobinemia Type IV | Anthrax | Acromegaly | Myocardial Infarction | Cardiospondylocarpofacial Syndrome | Adenoma, Pituitary | Angelman Syndrome | Oligoastrocytoma | Depression | IMAGe Syndrome | Vaginitis | Hyperammonemia | Infertility | Hydronephrosis | Oculodentodigital Dysplasia | Craniosynostosis | Hyperparathyroidism | Autism Spectrum Disorders | Adenoma, Pleomorphic | Restless Legs Syndrome | Spinocerebellar Ataxia Type 16 | Brenner Tumor | Basal Ganglia Cerebrovascular Disease | Eclampsia | Lymphomatoid Granulomatosis | Primrose Syndrome | Early Infantile Epileptic Encephalopathy 13 | Hypertension, Essential | Cerebral Cavernous Malformations | Encephalopathy | Prader-Willi Syndrome | Osteogenesis Imperfecta Type III | Retinal Dystrophy, Early-onset Severe | Acute Generalized Exanthematous Pustulosis | Arthrogryposis | Esotropia | Peripheral Neuropathy | Wilson's Disease | Basal Ganglia Disease, Biotin-responsive | Frontometaphyseal Dysplasia | Crimean-Congo Hemorrhagic Fever | Binge Eating Disorder | Basal Ganglia Disease | Dominant Optic Atrophy | Ichthyosis, X-linked | Huntington's Disease | Cone Dystrophy | Erectile Dysfunction | Osteonecrosis | Osteoporosis | B-cell Prolymphocytic Leukemia | Plasma Cell Leukemia | 3-M Syndrome | Short-chain Acyl-CoA Dehydrogenase Deficiency | Synovitis | Actinomycetoma | Retinopathy, Diabetic | Synpolydactyly | Opisthorchiasis | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Rift Valley Fever | Myelitis | Hereditary Xerocytosis | Pitt-Hopkins Syndrome | Acute Lymphocytic Leukemia | Corneal Dystrophy | Leukocyte Adhesion Deficiency Type 1 | Anodontia | Androgenic Alopecia | Jawad Syndrome | Rhabdomyosarcoma, Embryonal | CREST Syndrome | Peters-plus Syndrome | Alstrom Syndrome | Carcinoid Tumor | Non-proliferative Diabetic Retinopathy | Charcot-Marie-Tooth Disease Type 2D | Esophagitis, Eosinophilic | Distal Myopathy | Infantile Refsum Disease | Gray Platelet Syndrome | Oral Lichen Planus | Carotid Artery Disease | Renal Hypouricemia | Amelogenesis Imperfecta | Erythematotelangiectatic Rosacea | Polymyositis | Asplenia | Rubinstein-Taybi Syndrome | Lymphedema-distichiasis Syndrome | Multiple Sclerosis | Lymphoma, AIDS-related | Saul-Wilson Syndrome | Wolfram Syndrome | Anxiety Disorders | Cardiomyopathy, Restrictive | Lymphopenia | Aneurysm, Thoracic Aortic | Craniopharyngioma | Lateral Meningocele Syndrome