Corticobasal Syndrome

About the Disease
Corticobasal Syndrome is related to progressive supranuclear palsy-corticobasal syndrome and frontotemporal dementia. An important gene associated with Corticobasal Syndrome is TBK1 (TANK Binding Kinase 1). The drugs Fasudil and Calcium, Dietary have been mentioned in the context of this disorder. Affiliated tissues include brain, subthalamic nucleus and cortex, and related phenotypes are parkinsonism and progressive extrapyramidal muscular rigidity

Common Targets
GBA1 | ADORA1 | C9orf72 | Tubulin | ITM2B | ADORA2A | MOBP | GSK3B | G4137 | PRKAG2 | G7422 | LOC101929419 | APOE | OGA | TRIM11 | MAOB | Rho kinase (ROCK) (nonspecified subtype) | NR4A2 | GRN | G8878 | GRIN3B | LRRK2 | SOS1 | TSPEAR

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