Corticobasal Syndrome
Corticobasal Syndrome
About the Disease
Corticobasal Syndrome is related to progressive supranuclear palsy-corticobasal syndrome and frontotemporal dementia. An important gene associated with Corticobasal Syndrome is TBK1 (TANK Binding Kinase 1). The drugs Fasudil and Calcium, Dietary have been mentioned in the context of this disorder. Affiliated tissues include brain, subthalamic nucleus and cortex, and related phenotypes are parkinsonism and progressive extrapyramidal muscular rigidity
Common Targets
GBA1 | ADORA1 | C9orf72 | Tubulin | ITM2B | ADORA2A | MOBP | GSK3B | G4137 | PRKAG2 | G7422 | LOC101929419 | APOE | OGA | TRIM11 | MAOB | Rho kinase (ROCK) (nonspecified subtype) | NR4A2 | GRN | G8878 | GRIN3B | LRRK2 | SOS1 | TSPEAR
![疾病靶点研报](../img/disease-target-analysis-report.jpg)
Note: If you'd like to get a target analysis report for Corticobasal Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Corticobasal Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.
Other Diseases
Fibrosis | Whipple's Disease | Cancer, Colon | Xeroderma Pigmentosum | Hemangioma | Progressive External Ophthalmoplegia | Congenital Generalized Lipodystrophy | Chondromyxoid Fibroma | Chudley-McCullough Syndrome | Paget's Disease Of The Breast | Osteogenesis Imperfecta Type IV | Inborn Errors Of Metabolism | Anemia | Peripheral T-cell Lymphoma | Tinea Versicolor | Sleep Apnea | 3C Syndrome | Influenza | Cleidocranial Dysplasia | Myotonic Disorders | Sporadic Inclusion Body Myositis | Antiphospholipid Syndrome | Atrioventricular Septal Defect | Kaposiform Hemangioendothelioma | Ichthyosis, X-linked | Avian Influenza | Thymoma, Malignant | Angiodysplasia | Congenital Dyserythropoietic Anemia Type 4 | Usher Syndrome | Hepatitis D | Eczema | Cystinosis | Epilepsy | Dowling-Degos Disease | Joubert Syndrome 2 | Alopecia | Mast Cell Leukemia | Esotropia | Spinocerebellar Ataxia Type 15 | Werner's Syndrome | Palmoplantar Keratoderma | Prediabetes | Arts Syndrome | Macular Degeneration | Keratocystic Odontogenic Tumor | Gnathodiaphyseal Dysplasia | Adenylosuccinate Lyase Deficiency | McCune-Albright Syndrome | Brugada Syndrome 1 | Withdrawal Syndrome | Polyarteritis Nodosa | Insulinoma | Progressive Osseous Heteroplasia | Hypogammaglobulinemia | Pseudohypoparathyroidism Type 1B | Autosomal Recessive Bestrophinopathy | Hereditary Xerocytosis | Optic Neuropathy, Anterior Ischemic | Hypothalamic Obesity | Pneumonia, Mycoplasma | Loeys-Dietz Syndrome Type 4 | Muir-Torre Syndrome | Bicuspid Aortic Valve | Generalized Epilepsy And Paroxysmal Dyskinesia | Long QT Syndrome Type 3 | Fibronectin Glomerulopathy | Myelitis | Charcot-Marie-Tooth Disease Type 4D | Ureteropelvic Junction Obstruction | Sotos Syndrome | Premature Ejaculation | Keloid | Aneurysm, Thoracic Aortic | Spastic Paraplegia Type 7 | Best Macular Dystrophy | Sturge-Weber Syndrome | Aceruloplasminemia | Familial Episodic Pain Syndrome | Leiomyoma | Diffuse Intrinsic Pontine Glioma | Krabbe Disease | Macrophagic Myofasciitis | Asthma, Exercise-induced | Endometritis | Early Infantile Epileptic Encephalopathy 13 | Primary Hyperoxaluria | Usher Syndrome Type I | Genitopatellar Syndrome | Stroke | Bartsocas-Papas Syndrome | Pure Red Cell Aplasia | Osteochondroma | Plasma Cell Dyscrasia | ICF Syndrome | Thrombocytopenia | Photosensitivity | Micropenis | Gastroschisis | Atopic Dermatitis | Amenorrhea | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Pseudohypoparathyroidism Type 2 | Allergic Contact Dermatitis | Anterior Segment Dysgenesis | Erythematotelangiectatic Rosacea | Basal Ganglia Cerebrovascular Disease | Smoldering Myeloma | Miyoshi Myopathy | Primary Cutaneous Amyloidosis | HANAC Syndrome | Blepharo-cheilo-odontic Syndrome | Cherubism | Erythromelalgia | Speech Disorders | Barakat Syndrome | Dystrophy, Cone-rod | Thyroiditis | Guillain-Barre Syndrome | Schizophrenia, Paranoid | Leri-Weill Dyschondrosteosis | Salla Disease | Diverticulitis | Sarcoma | Aplastic Anemia | Renal Tubular Acidosis | Kallmann Syndrome | Lathosterolosis | Megaloblastic Anemia | Asthma | Hypereosinophilic Syndrome | Sick Sinus Syndrome | Primary Erythromelalgia | Acrodermatitis Enteropathica | Carcinoma, Merkel Cell | Blau Syndrome | Coronary Restenosis | Sclerocornea | Heimler Syndrome | Microphthalmia | B-cell Prolymphocytic Leukemia | Tylosis With Esophageal Cancer | Smith-Kingsmore Syndrome | Polyneuropathy | Osteosarcoma | Mycosis Fungoides | Metatropic Dysplasia | Congenital Bilateral Absence Of Vas Deferens | Chromosome 16p11.2 Deletion Syndrome | Nephropathy | Carbohydrate Metabolism Disorders | Burn-McKeown Syndrome | Saul-Wilson Syndrome | Astrocytoma, Anaplastic | Pantothenate Kinase-associated Neurodegeneration | Amelanotic Melanoma | Mosaic Variegated Aneuploidy Syndrome 2 | Desmosterolosis | Long QT Syndrome Type 1 | Congenital Torticollis | Tenosynovial Giant Cell Tumor | Greig Cephalopolysyndactyly Syndrome | Corneal Ulcer | Microtia | Spinocerebellar Ataxia Type 27 | Birk-Barel Syndrome | Lupus Erythematosus | Hemangioblastoma | Angelman Syndrome | Pulmonary Stenosis | POEMS Syndrome | Mandibuloacral Dysplasia With Type A Lipodystrophy | Medulloblastoma | Fucosidosis | Nestor-Guillermo Progeria Syndrome | Spasticity | Hereditary Hemorrhagic Telangiectasia | Split Hand-foot Malformation | Cavitary Optic Disc Anomalies | Loeys-Dietz Syndrome | Blepharoconjunctivitis | Cole-Carpenter Syndrome | Necrotizing Autoimmune Myopathy | Acute Tubular Necrosis | Oculodentodigital Dysplasia | Ophthalmoplegia | Nemaline Myopathy 8 | Angiosarcoma | Parapsoriasis | Restrictive Dermopathy | Meckel-Gruber Syndrome | Ganglioglioma | Juvenile Hyaline Fibromatosis | Teratozoospermia | Beckwith-Wiedemann Syndrome | Nager Acrofacial Dysostosis | Familial Hyperaldosteronism | Conduct Disorder | Encephalitis | Pituitary Disorders | Sialoadenitis | Mevalonate Kinase Deficiency | Oligospermia | Leri Pleonosteosis | Cri-du-chat Syndrome | Congenital Ichthyosiform Erythroderma | Multicystic Renal Dysplasia | Gastroenteritis | Myocardial Infarction | Waardenburg Syndrome Type 4A | Melanoma, Malignant | Calcium Pyrophosphate Deposition Disease | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Lennox-Gastaut Syndrome | Gestational Trophoblastic Disease | Lymphedema-distichiasis Syndrome | Osteomyelitis | Charcot-Marie-Tooth Disease Axonal Type 2N | Pneumonia, Viral | Ovarian Hyperstimulation Syndrome | Intestinal Pseudo-obstruction | Herpes Simplex Dermatitis | Systemic Mastocytosis | Keratitis-ichthyosis-deafness Syndrome | Chronic Beryllium Disease | Hepatitis | Tumoral Calcinosis | Osteogenesis Imperfecta Type I | DNA Ligase IV Deficiency | Cardiomyopathy, Restrictive | Fanconi Syndrome | Tularemia | Colorectal Adenoma | Retinopathy Of Prematurity | Dystonia | Glaucomatocyclitic Crisis | Senior-Loken Syndrome | Endophthalmitis | Neurofibromatosis-Noonan Syndrome | Vitelliform Macular Dystrophy | Stuve-Wiedemann Syndrome | Hyperthermia, Malignant | Rotor Syndrome | Birt-Hogg-Dube Syndrome | Poirier-Bienvenu Neurodevelopmental Syndrome | Evans Syndrome | Iron Overload | Hypotrichosis Simplex | Charcot-Marie-Tooth Disease Type 3 | Cryptosporidiosis | Neurofibromatosis | Lentigo | Dental Caries | Pancreatitis | Atrial Septal Defect | Pineoblastoma | Gastritis, Atrophic | Onchocerciasis | Anencephaly | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Rhizomelic Chondrodysplasia Punctata | Language Disorders | Postaxial Polydactyly | Sarcoidosis, Pulmonary | Leukoplakia, Oral | Chylomicron Retention Disease | Generalized Epilepsy With Febrile Seizures Plus | Chronic Enteropathy Associated With SLCO2A1 Gene | Eccrine Porocarcinoma | Hydrocephalus | Myopia | Erdheim-Chester Disease | Prune Belly Syndrome | Hepatitis, Chronic | Dermatomyositis | Still Disease | GLUT1 Deficiency Syndrome | Binge Eating Disorder | Aldosteronism | Succinic Semialdehyde Dehydrogenase Deficiency | Thyroid Dyshormonogenesis | Distal Myopathy | Primary Hyperoxaluria Type 3 | Ovarian Sex Cord-stromal Tumor | Methylmalonic Aciduria And Homocystinuria, CblC Type | Graves Disease | Cat Eye Syndrome | Epithelial-myoepithelial Carcinoma | Methemoglobinemia Type IV | Myoclonus | Craniometaphyseal Dysplasia | Neurogenic Bladder | Autism | Toxoplasmosis | Skin Carcinoma | Twin-to-twin Transfusion Syndrome | Sarcosinemia | Patent Ductus Arteriosus | Oguchi Disease-2 | Behcet's Disease | Periventricular Nodular Heterotopia | Alopecia Totalis | Gerstmann-Straussler-Scheinker Syndrome | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Kohlschutter-Tonz Syndrome | Frank-ter Haar Syndrome | Malnutrition | Castleman Disease | Discoid Lupus Erythematosus | Sensory Neuropathy | Spinal Muscular Atrophy | Gitelman Syndrome | Pycnodysostosis | Premenstrual Syndrome | Acute Lymphocytic Leukemia | Neuroleptic Malignant Syndrome | Relapsing Polychondritis | Charcot-Marie-Tooth Disease, Type 2C | Spondyloepiphyseal Dysplasia Tarda, X-linked | Acanthosis Nigricans | Cardiac Arrest | Focal Segmental Glomerulosclerosis | Autonomic Neuropathy | Bacterial Meningitis | Chloridorrhea, Congenital | Schindler Disease | Charcot-Marie-Tooth Disease Type 2D | Glycogen Storage Disease Type 0, Muscle | Tyrosinemia Type 1 | Globozoospermia | Melanocytic Nevus | Limb Girdle Muscular Dystrophy | Gingivitis | Tibial Muscular Dystrophy | Macular Corneal Dystrophy | Familial Advanced Sleep Phase Syndrome | Multiple System Atrophy | Blomstrand Osteochondrodysplasia | Pfeiffer Syndrome | Pelvic Inflammatory Disease | Varices | Multiple Sclerosis, Secondary Progressive | Heterotaxy | Usher Syndrome Type II | Encephalocele | Autosomal Recessive Congenital Ichthyosis | Neurofibroma | H Syndrome | Congestive Heart Failure | Farber Disease | Carcinoma, Squamous Cell | Liddle Syndrome | Hyperinsulinemic Hypoglycemia | Nance-Horan Syndrome | Hypoplastic Left Heart Syndrome | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Cluster Headache | Branchiootorenal Syndrome | Lissencephaly 2 | Cutis Laxa | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Congenital Lipoid Adrenal Hyperplasia | Ocular Hypertension | Johanson-Blizzard Syndrome | Vertigo | LEOPARD Syndrome | Adrenomyeloneuropathy | Crimean-Congo Hemorrhagic Fever | Histiocytic Sarcoma | Familial Male-limited Precocious Puberty | Sarcoma, Endometrial Stromal | Asperger Syndrome | Spinocerebellar Ataxia Type 6 | Aplasia Cutis Congenita | Lamellar Ichthyosis | Isobutyryl-CoA Dehydrogenase Deficiency | Spinocerebellar Ataxia | Blastomycosis | Porphyria, Acute Intermittent | Cutaneous Mastocytosis | Familial Pheochromocytoma-paraganglioma | Smith-Magenis Syndrome | Congenital Dyserythropoietic Anemia Type 1 | Barrett Esophagus | Myelomeningocele | Myopathy | Mitochondrial DNA Depletion Syndrome | Coronary Heart Disease | Pernicious Anemia | Conjunctivitis, Allergic | Tetanus | Pulverulent Zonular Cataract | Primary Progressive Nonfluent Aphasia | Encephalopathy, Hepatic | Thyroid Dysgenesis | Anorectal Fistula | Poikiloderma With Neutropenia | Charcot-Marie-Tooth Disease, Type 1A | Creutzfeldt-Jakob Disease | Thanatophoric Dysplasia Type 1