Oculodentodigital Dysplasia

About the Disease
Oculodentodigital Dysplasia, also known as odd syndrome, is related to syndactyly, type iii and hypomyelinating leukodystrophy. An important gene associated with Oculodentodigital Dysplasia is GJA1 (Gap Junction Protein Alpha 1), and among its related pathways/superpathways are Vesicle-mediated transport and Gap junction trafficking. The drugs Ethanol and Nivolumab have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and bone, and related phenotypes are carious teeth and cleft palate

Common Targets
GJA1

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