Male Infertility

About the Disease
Male Infertility, also known as infertility, male, is related to spermatogenic failure 9 and infertility, and has symptoms including subfertility, male, inability to conceive due to male infertility and inability to impregnate. An important gene associated with Male Infertility is CFTR (CF Transmembrane Conductance Regulator), and among its related pathways/superpathways are Male infertility and Ovarian infertility. The drugs Progesterone and Dydrogesterone have been mentioned in the context of this disorder. Affiliated tissues include Testis, and related phenotypes are no effect and no effect

Common Targets
AKAP4 | CFAP44 | CDK2 | TTLL10 | COX2 | DDX25 | SPAG17 | MNS1 | G3320 | ZNF114 | CREM | TNFRSF1B | SEMA5A | TAS2R38 | IL1RN | TAFA5 | CFAP65 | ACTL9 | PMFBP1 | SLC9C1 | MEG3 | ZNF438 | MSH3 | TTC12 | PLCZ1 | RBMXL3 | BMAL1 | ETV5 | MYT1L | NOS1 | SPEF2 | RPL23AP82 | USP26 | KCNH5 | ACE | TSGA10 | ILKAP | ADARB2 | KDM4C | FSHR | ZNF888 | BCAN | LPAR1 | G4780 | NPHP4 | VPS13B | RIMBP2 | HLA-DQA1 | BRD2 | MEIOB | CFAP47 | H2BW1 | ZEB2 | ITGA2B | ESR2 | KATNAL2 | CDK5 | CYP1A1 | COL4A1 | ND1 | F11-AS1 | TEX15 | TP73 | BRD4 | KEAP1 | TAF4 | MIR34B | Estrogen receptor (nonspecified subtype) | PEG3 | SRD5A2 | EBF3 | OGG1 | TNFSF11 | ADGRA1 | PTDSS2 | CRISPLD1 | IQCN | SNRPN | CSTPP1 | MTRR | TPP2 | DEFB126 | LEP | CXADRP3 | MDC1 | KITLG | SMPD1 | ABCA1 | FAT2 | GRAMD4P7 | MISP | DNAH5 | NFKBIA | NR5A1 | CDKL3 | INHA | ACR | HSD11B1 | ND2 | SATL1 | KLK3 | RAB12 | YBX2 | CFAP43 | ADA | SOX8 | DNAH6 | MIR34C | CEP290 | PDPK1 | TDRD1 | ADAM20 | FGF9 | CETN1 | DNAH1 | GSTT1 | PIWIL2 | TTLL8 | SLC19A1 | DNAH8 | NUP210L | MLH3 | SMYD3 | MAP4K1 | CPEB2 | TGM3 | MTHFD1 | ACTL7A | ND3 | TNP1 | UBR2 | OR2W3 | HOXB1 | SGO1 | LRRC37A16P | LHCGR | G7124 | LRCH2 | DNAH2 | G4318 | NR3C1 | BOLL | TNR | DNAH12 | POLG | RABL2B | CBS | GNRHR | M1AP | AURKC | RABL2A | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | Retinoid acid receptor (nonspecified subtype) | GABBR2 | FIS1 | G4193 | KCNJ5 | SEPTIN12 | G367 | NSFP1 | DNAH17 | KCNQ1OT1 | WWC2 | LEPR | KIR2DL1 | P2X Receptor (nonspecified subtype) | ELOA3BP | ND4 | AMDHD1 | PIK3R6 | SNURF | IL1A | G5243 | PTPRN2 | FSIP2 | VDR | NOS3 | NR6A1 | KCNQ1 | G196 | MMP2 | HSPA1A | CATSPER1 | SPO11 | PACRG | GPX4 | MTHFR | ADIPOR2 | SPATA22 | PDE5A | SPPL2C | GPRC6A | ND4L | POTEG | MDGA2 | ATP6 | SLC6A14 | ESCO2 | PIWIL1 | TIMP2 | DEFB128 | NOS2 | ARMC2 | MAGI1 | PSG4 | CFAP251 | CFAP69 | SPATA16 | GSTM1 | PRM1 | CFTR | LINC01060 | TTC29 | IGFBPL1 | RNF138P1 | GHRHR | ACSS3 | GSTP1 | CEP350 | CYP1B1 | MEST | GATA3 | PRM2 | KIAA1210 | SLC5A4-AS1 | PLEKHG4B | CYP19A1 | VDAC2 | QRICH2 | RPL23AP7 | ARSA | LRP8 | HSPA1L | ODF3 | MTR | STAG3 | XRCC1 | PLPP1 | EEA1 | DOCK9 | ATP2B4 | HLA-DRB6 | MLH1 | H19 | ADGRL3 | HASPIN | HLA-C | MIR499A | FSHB | PTGER2 | TMEM243 | IGF2 | CLOCK | SHMT1 | CC2D1B | SUN5 | TPTE2 | BRDT | MOV10L1 | DNAH10 | NUDT13 | CCDC7 | CICP5 | TCERG1L | DAZL | CARD8 | CFAP58 | LINGO2 | WNT5A | CAT

Note: If you'd like to get a target analysis report for Male Infertility, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Male Infertility at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Acute Myeloid Leukemia | Hypertriglyceridemia | Brachydactyly | Osteogenesis Imperfecta Type IV | Tendinitis | Lafora Disease | Hypobetalipoproteinemias | Aarskog-Scott Syndrome | Wolman Disease | Beckwith-Wiedemann Syndrome | Stroke, Ischemic | Oculocutaneous Albinism | Acrodermatitis Enteropathica | Thrombotic Microangiopathy | Spinocerebellar Ataxia Type 16 | Glycogen Storage Disease | Fanconi Syndrome | Primary Sclerosing Cholangitis | Loeys-Dietz Syndrome Type 4 | Nail-Patella Syndrome | Trichothiodystrophy | Melanocytic Nevus | X-linked Acrogigantism | Mumps | Inflammatory Myofibroblastic Tumor | Charcot-Marie-Tooth Disease, Type 2C | Smith-Kingsmore Syndrome | Lichen Sclerosus | Erythromelalgia | Renpenning Syndrome | Hyperandrogenemia | Osteoporosis-pseudoglioma Syndrome | Wiedemann-Steiner Syndrome | Down Syndrome | Poirier-Bienvenu Neurodevelopmental Syndrome | Hypotension, Orthostatic | Xeroderma Pigmentosum | Hereditary Hemorrhagic Telangiectasia | Congenital Primary Aphakia | Sclerocornea | Triphalangeal Thumb-polysyndactyly Syndrome | Spinocerebellar Ataxia Type 23 | Cryptorchidism | Pterygium | Chondrosarcoma | Macular Degeneration | PHARC Syndrome | Pyelonephritis | Dentinogenesis Imperfecta | Hereditary Spastic Paraplegia | Microcephaly | Bainbridge-Ropers Syndrome | Esophagitis | Erysipelas | Pneumonia, Viral | Pseudohypoparathyroidism Type 1A | Primrose Syndrome | Albinism | Androgenic Alopecia | Pompe Disease | Keratoacanthoma | Congenital Dyserythropoietic Anemia Type 4 | Hypokalemic Periodic Paralysis | Gerstmann-Straussler-Scheinker Syndrome | Juvenile Xanthogranuloma | Brooke-Spiegler Syndrome | Varices | Seborrheic Dermatitis | HUPRA Syndrome | Sarcoma, Ewing | Osteoglophonic Dysplasia | Erectile Dysfunction | Aplasia Cutis Congenita | Gigantism | Spinocerebellar Ataxia Type 6 | Polyarteritis Nodosa | Perivascular Epithelioid Cell Tumor | Charcot-Marie-Tooth Disease, Type 1A | Hypogammaglobulinemia | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Olmsted Syndrome | Scleritis | Pseudohypoaldosteronism | Waardenburg Syndrome Type 4A | Fetal Akinesia Deformation Sequence | Pseudohypoparathyroidism Type 2 | Hypercholesterolemia, Familial | Pulmonary Stenosis | Mucolipidosis Type II | Keratosis | Systemic Lupus Erythematosus | Metaphyseal Chondrodysplasia, Schmid Type | Hyperuricemic Nephropathy, Familial Juvenile | Myotonic Disorders | Inflammatory Bowel Disease | Transthyretin-related Amyloidosis | Primary Carnitine Deficiency | Microphthalmia, Syndromic 7 | Cystinuria | Tinea | Hepatitis C, Chronic | Thrombocytopenia | Werner's Syndrome | Optic Nerve Diseases | Cystinosis | Meningioma, Benign | Renal Dysplasia | Gerodermia Osteodysplastica | Goiter | Heavy Chain Disease | Mitochondrial DNA Depletion Syndrome | Exfoliative Dermatitis | Pulmonary Sclerosing Hemangioma | Optic Neuropathy, Anterior Ischemic | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Intermittent Claudication | Retinopathy Of Prematurity | Fraser Syndrome | Mohr-Tranebjaerg Syndrome | Malignant Peripheral Nerve Sheath Tumor | Hemolytic Uremic Syndrome, Atypical | Hydrolethalus Syndrome | Sweet Syndrome | Mesothelioma, Malignant | Hyperostosis | Hereditary Xerocytosis | Megalencephaly | Sporadic Inclusion Body Myositis | Encephalitis, Tick-borne | Liver Failure | Waardenburg Syndrome Type 2A | Spinocerebellar Ataxia Type 15 | Bone Marrow Necrosis | Birt-Hogg-Dube Syndrome | Meier-Gorlin Syndrome | Multiple Hamartoma Syndrome | Uterine Leiomyoma | X-linked Creatine Transporter Deficiency | Familial Advanced Sleep Phase Syndrome | Neuromuscular Disorders | Angioedema, Hereditary | Pure Red Cell Aplasia | Myosin Storage Myopathy | Tracheal Disorders | Congenital Muscular Dystrophy | Transient Bullous Dermolysis Of The Newborn | Neurofibroma | Nevus | Hypokalemia | Citrullinemia | Scleroderma, Diffuse | Schistosomiasis Mansoni | Subacute Sclerosing Panencephalitis | Myeloid Leukemia | Epidermolytic Palmoplantar Keratoderma | Ovarian Hyperstimulation Syndrome | Gyrate Atrophy Of The Choroid And Retina | Hypertension, Renal | Ichthyosis | Niemann-Pick Disease, Type C | Diffuse Palmoplantar Keratoderma | Agammaglobulinemia | Leukocyte Adhesion Deficiency Type 1 | Chondrodysplasia Punctata 2, X-linked Dominant | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Blepharophimosis Syndrome | Leukocyte Adhesion Deficiency | Chromosome 9q34.3 Deletion Syndrome | Epilepsy, Generalized | Giant Cell Glioblastoma | Hemolytic Anemia | Congenital Aniridia | Periodontitis | Carcinoid Syndrome | Double Outlet Right Ventricle | Blau Syndrome | Alpha-mannosidosis | Allergic Contact Dermatitis | LEOPARD Syndrome | Basal Ganglia Disease | Cavitary Optic Disc Anomalies | Pancytopenia | Histiocytosis | C3 Glomerulopathy | Swine Influenza | Carcinoma, Merkel Cell | Chondrodysplasia Punctata 1, X-linked Recessive | Takenouchi-Kosaki Syndrome | Congenital Hemolytic Anemia | Pierre Robin Syndrome | Hartsfield Syndrome | Cerebellofaciodental Syndrome | Open-angle Glaucoma | Aldosteronism | Measles | Mood Disorder | Danon Disease | Stromal Corneal Dystrophy | Vici Syndrome | Scapuloperoneal Spinal Muscular Atrophy | Basal Ganglia Disease, Biotin-responsive | Ollier Disease | Best Macular Dystrophy | Anorexia Nervosa | Joubert Syndrome 2 | Esophageal Adenocarcinoma | Van Der Knaap Disease | Cluster Headache | Papilledema | Chronic Mucocutaneous Candidiasis | Keratopathy | Intellectual Disability, Autosomal Dominant 5 | B-cell Chronic Lymphocytic Leukemia | Melnick-Needles Syndrome | Erdheim-Chester Disease | Dubin-Johnson Syndrome | Pontocerebellar Hypoplasia | Endocarditis | Schizophrenia, Paranoid | Tricho-hepato-enteric Syndrome | Vitreoretinopathy, Proliferative | Alveolar Capillary Dysplasia | Postpartum Depression | Craniofacial Dysostosis | Renal-hepatic-pancreatic Dysplasia | Heimler Syndrome | Glioblastoma | Papillorenal Syndrome | Intracerebral Hemorrhage | Glomerulonephritis, Membranoproliferative | Retinitis Pigmentosa 3 | Pitt-Hopkins Syndrome | Emery-Dreifuss Muscular Dystrophy | Bulimia Nervosa | Riboflavin Transporter Deficiency Neuronopathy | Retinal Degeneration | Cutis Laxa | ICF Syndrome | Malonyl-CoA Decarboxylase Deficiency | Osteogenesis Imperfecta Type III | Corneal Dystrophy And Perceptive Deafness | Cleidocranial Dysplasia | Panuveitis | Neuroma | Hypopituitarism | IgA Nephropathy | Precocious Puberty | Epidermal Nevus Syndrome | Blood Protein Disorders | Interstitial Lung Diseases | Congenital Disorders Of Glycosylation | Mannosidase Deficiency Diseases | Myotonia | Glutaric Aciduria Type 3 | Coloboma | Borderline Personality Disorder | Dental Caries | Shock, Cardiogenic | Waldenstrom Macroglobulinemia | Intestinal Pseudo-obstruction | Histoplasmosis | Spinocerebellar Ataxia Type 27 | Infertility, Male | SAPHO Syndrome | Acute Kidney Injury | Hyperparathyroidism, Primary | Cornelia De Lange Syndrome | Hyperacusis | Carcinoma, Squamous Cell | Rhabdomyosarcoma, Alveolar | Dwarfism | Rickets | PASLI Disease | Diffuse Intrinsic Pontine Glioma | Amelanotic Melanoma | Primary Aldosteronism | Atrial Septal Defect | CREST Syndrome | Blue Rubber Bleb Nevus Syndrome | Neurofibrosarcoma | Traboulsi Syndrome | Anthrax | Hemophilia | Epidermodysplasia Verruciformis | Moyamoya Disease | Angiosarcoma Of The Breast | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Frank-ter Haar Syndrome | Nephrotic Syndrome Type 1 | Lymphopenia | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Gitelman Syndrome | Esophageal Motility Disorders | Chordoid Glioma | Acromicric Dysplasia | Proopiomelanocortin Deficiency | B-cell Prolymphocytic Leukemia | Micro Syndrome | Glutathione Synthetase Deficiency | Farber Disease | Congenital Myopathy | Chondroma | Cramp Fasciculation Syndrome | Guillain-Barre Syndrome | Blastomycosis | Tumoral Calcinosis | Varicocele | Erythrokeratodermia Variabilis | Charcot-Marie-Tooth Disease Type 4E | Acne Vulgaris | Progressive External Ophthalmoplegia | Diabetes Insipidus | Hyperinsulinemia | Vestibular Disease | Partington Syndrome | Ichthyosis, X-linked | Lassa Fever | Syncope | Inflammatory Joint Disease | Lysosomal Acid Lipase Deficiency | Duodenal Atresia | Leukemia | Pemphigus Foliaceus | Presbycusis | Alcoholism | Generalized Epilepsy With Febrile Seizures Plus | Spondylosis | Hypoglycemia | Hypersensitivity Pneumonitis | Conjunctivitis, Allergic | Hepatorenal Syndrome | Spondylometaphyseal Dysplasia | Hypohidrotic Ectodermal Dysplasia, X-linked | Colitis, Lymphocytic | Cancer, Breast | Urea Cycle Disorder | Pemphigus | Evans Syndrome | Rotor Syndrome | Adenocarcinoma | Bicuspid Aortic Valve | Aromatic L-amino Acid Decarboxylase Deficiency | Alopecia Areata | Dementia, Vascular | Usher Syndrome Type IIC | Fragile X Syndrome | Cystitis | Exocrine Pancreatic Insufficiency | Erythema Multiforme | Growth Hormone Excess | Oculocutaneous Albinism Type 1 | Retinal Diseases | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Cardiomyopathy, Restrictive | Arthrogryposis | Cysticercosis | Galloway-Mowat Syndrome | Vaginitis | Kashin-Beck Disease | Sezary Syndrome | Adenoma, Pituitary | Lipid Metabolism Disorders | Schnyder Crystalline Corneal Dystrophy | Retinal Vasculitis | Tuberculous Meningitis | Aspartylglycosaminuria | Familial Glucocorticoid Deficiency | Carey-Fineman-Ziter Syndrome | Short-chain Acyl-CoA Dehydrogenase Deficiency | Arthritis | Heart Block | Polyomavirus Nephropathy | Sandhoff Disease | Renal Oncocytoma | Lymphangiomatosis | Adenomyosis | Blepharospasm | Hermansky-Pudlak Syndrome | Keratoconjunctivitis | Venous Insufficiency | Scapuloperoneal Myopathy, X-linked Dominant | Discoid Lupus Erythematosus | Myelomeningocele | Agranulocytosis | GLUT1 Deficiency Syndrome | Low Tension Glaucoma | Lupus Erythematosus | Wolfram Syndrome 2 | Localized Scleroderma | Cabezas Syndrome | Paget's Disease Of The Breast | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Gastroschisis | Sialoadenitis | Insulin Resistance | Nicotine Dependence | Neurofibromatosis Type 2 | Aneurysm, Abdominal Aortic | Hypoalbuminemia | Diarrhea