Disease

Lewy Body Dementia

About the Disease
Dementia, Lewy Body, also known as lewy body dementia, is related to parkinson disease 4, autosomal dominant and parkinson disease 1, autosomal dominant, and has symptoms including back pain, headache and pain. An important gene associated with Dementia, Lewy Body is SNCA (Synuclein Alpha), and among its related pathways/superpathways are Neuroscience and Copper homeostasis. The drugs Memantine and Donepezil have been mentioned in the context of this disorder. Affiliated tissues include brain, bone marrow and eye, and related phenotypes are dementia and visual hallucinations

Common Targets
PSEN1 | SLC18A2 | G4233 | LRP10 | Voltage-Gated Sodium Channel Complex | LOC105377329 | CHRM4 | CHRM1 | ABI3 | Sodium channel (nonspecified subtype) | LCK | MUC19 | BCR | LAG3 | IL1B | T-Type Calcium Channel | DYRK1A | DPP4 | G3480 | NTRK1 | VPS35 | UGCG | WWOX | FLT3 | NTRK3 | PDE9A | SLC18A3 | BCHE | SMPD1 | HTR2A | NF-kappaB (NFkB) | GPR3 | G4137 | CLU | ANK1 | MED12L | JAK2 | NMDA receptor | FGFR4 | TFAM | VHL | ABCC8 | FABP3 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | JAK1 | GABRB3 | ABCC9 | KDM1A | HEXA | APOE | BACE1 | ATP7B | LYN | HTR6 | alpha1-Adrenoceptor (nonspecified subtype) | NUAK1 | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | OGA | G5133 | APP | GABRA5 | ABL1 | CHCHD2 | TMEM97 | TNK2 | SMPD3 | SLC6A3 | FYN | CHRM5 | DYRK1B | MAOB | FGFR2 | BCKDK | KCNJ8 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | SNCB | CHRM2 | PRKN | NTRK2 | SORL1 | GRN | VPS13C | BCL7C | CASP6 | PGK1 | Major histocompatibility complex class II antigens (nonspecified subtype) | GALC | FGL1 | SNCA | FGFR3 | RIPK2 | LRRK2 | KCNJ11 | PLCG2 | SNCA-AS1 | MAOA | PREP | SLC6A2 | Alpha-2 Adrenergic receptors (nonspecified subtype) | ACHE | TOMM40 | SLC9A1 | G3569 | FGFR1 | GBA1

疾病靶点研报
Lewy Body Dementia

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