Prolidase Deficiency

About the Disease
Prolidase Deficiency, also known as hyperimidodipeptiduria, is related to paroxysmal extreme pain disorder and splenomegaly, and has symptoms including petechiae of skin An important gene associated with Prolidase Deficiency is PEPD (Peptidase D). Affiliated tissues include skin, spleen and liver, and related phenotypes are hearing impairment and depressed nasal bridge

Common Targets
PEPD

Note: If you'd like to get a target analysis report for Prolidase Deficiency, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Prolidase Deficiency at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

GATA2 Deficiency | Paroxysmal Nocturnal Hemoglobinuria | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Congenital Sodium Diarrhea | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Analgesia | Hypocalcemia | CHOPS Syndrome | Multifocal Motor Neuropathy | Blood Protein Disorders | Lassa Fever | Cancer, Brain | Congenital Tufting Enteropathy | Dowling-Degos Disease | Common Cold | Angina Pectoris | Distal Myopathy 2 | Congenital Afibrinogenemia | Eccrine Porocarcinoma | Fibromuscular Dysplasia | Phosphoglycerate Dehydrogenase Deficiency | Epidermolytic Palmoplantar Keratoderma | Homocystinuria | Hyperandrogenemia | Seizures | Diabetic Macular Edema | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Neurogenic Bladder | Hypotension, Orthostatic | Facioscapulohumeral Muscular Dystrophy | Schwannomatosis | Intracranial Hypertension | Chronic Enteropathy Associated With SLCO2A1 Gene | Lentigo | Retinal Telangiectasia | Specific Granule Deficiency | Paraganglioma, Carotid Body | Pathological Gambling | Basal Ganglia Cerebrovascular Disease | Lymphoma, B-cell | Neurofibroma | Beckwith-Wiedemann Syndrome | Autoimmune Autonomic Ganglionopathy | Thrombocytopenia | Acanthosis Nigricans | Inflammatory Joint Disease | Pregnancy, Ectopic | Pemphigus | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Paracoccidioidomycosis | Thanatophoric Dysplasia Type 1 | Osteogenesis Imperfecta Type VI | Angioedema | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Crouzon Syndrome With Acanthosis Nigricans | Molybdenum Cofactor Deficiency | Hyperekplexia | Dysequilibrium Syndrome | Glycogen Storage Disease Type 0, Muscle | Intracerebral Hemorrhage | Spondyloperipheral Dysplasia | Pouchitis | Batten Disease | Low Phospholipid Associated Cholelithiasis | Alexander Disease | Anterior Segment Dysgenesis | Metachondromatosis | Erythema Nodosum | Trichotillomania | Nicotine Dependence | Veno-occlusive Disease | Cryptorchidism | Perivascular Epithelioid Cell Tumor | Familial Exudative Vitreoretinopathy | Renal Oncocytoma | Primrose Syndrome | Potocki-Shaffer Syndrome | Pulmonary Vein Stenosis | Peripheral T-cell Lymphoma | Hypercholesterolemia, Familial | Multiple Epiphyseal Dysplasia | Dermatitis Herpetiformis | Nasodigitoacoustic Syndrome | Sarcoidosis, Pulmonary | LMNA-related Congenital Muscular Dystrophy | Usher Syndrome Type I | Teratozoospermia | Anodontia | Multicystic Renal Dysplasia | Microcephaly | Spondyloarthritis | Cancer, Bladder | Spondylometaphyseal Dysplasia | Primary Progressive Aphasia | Woodhouse-Sakati Syndrome | Tricho-hepato-enteric Syndrome | Acrocallosal Syndrome | Renal Failure | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Pneumothorax | Kaposiform Hemangioendothelioma | Hyperoxaluria | Autosomal Recessive Bestrophinopathy | Influenza | Imerslund-Grasbeck Syndrome | Mycosis Fungoides | Epicondylitis | Charcot-Marie-Tooth Disease Type 4 | Scleroderma | Coronary Artery Disease | Alazami Syndrome | Pituitary Dwarfism | Cryptococcal Meningitis | Gastrointestinal Disorders | Warsaw Breakage Syndrome | Epidermodysplasia Verruciformis | Hypermethioninemia | Opisthorchiasis | Creatine Deficiency Syndrome Due To AGAT Deficiency | Combined Deficiency Of Factor V And Factor VIII | Hypotonia-cystinuria Syndrome | Familial Hemiplegic Migraine | Erythropoietic Protoporphyria | Endophthalmitis | Panniculitis | Enhanced S-cone Syndrome | Nanophthalmos | Barrett Esophagus | NDH Syndrome | Crigler-Najjar Syndrome | Acrodermatitis Enteropathica | Majeed Syndrome | Adenoma, Pleomorphic | Azoospermia | Dystrophy, Cone-rod | Endometriosis | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Bulimia Nervosa | Anuria | Lymphoma Lymphoblastic | Isovaleric Acidemia | Retinal Detachment | Congenital Fiber-type Disproportion Myopathy | Hereditary Spherocytosis | Melanoma, Malignant | Blomstrand Osteochondrodysplasia | Dubin-Johnson Syndrome | B-cell Chronic Lymphocytic Leukemia | Asphyxia Neonatorum | Chondromyxoid Fibroma | Pseudohypoparathyroidism Type 1C | Neonatal Progeroid Syndrome | Triple A Syndrome | Niemann-Pick Disease, Type A | Mitochondrial Cytopathy | Learning Disability | Neutrophilia | Creutzfeldt-Jakob Disease | Smith-Magenis Syndrome | Takayasu's Arteritis | Astrocytoma, Anaplastic | Thrombosis | Colitis | Adenosine Deaminase Deficiency | Congenital Primary Aphakia | 3C Syndrome | Light Chain Amyloidosis | Shock, Cardiogenic | Ocular Albinism Type 1 | Hepatitis B, Chronic | Dengue Hemorrhagic Fever | Persistent Fetal Circulation | Niemann-Pick Disease, Type B | Sorsby Fundus Dystrophy | Mood Disorder | Methemoglobinemia | Autoimmune Hemolytic Anemia | Moyamoya Disease | Acromesomelic Dysplasia | Myeloid Leukemia | Lymphangioleiomyomatosis | Pantothenate Kinase-associated Neurodegeneration | Papulopustular Rosacea | Sengers Syndrome | Small Lymphocytic Lymphoma | Aldosteronism | Chronic Myeloid Leukemia | Anti-NMDA Receptor Encephalitis | Blastoma, Pleuropulmonary | Amelogenesis Imperfecta | Poirier-Bienvenu Neurodevelopmental Syndrome | Psoriasis | Split Hand-foot Malformation | Graft-versus-host Disease | Malonyl-CoA Decarboxylase Deficiency | Meconium Ileus | Tibial Muscular Dystrophy | Danon Disease | Usher Syndrome Type IIC | Neurofibromatosis Type 2 | Hemophagocytic Lymphohistiocytosis | Ectopia Lentis, Isolated, Autosomal Recessive | Cole-Carpenter Syndrome | Pyelonephritis | Central Retinal Artery Occlusion | Histiocytosis | Heterotopic Ossification | Tremor | Geleophysic Dysplasia | Empyema | Gardner Syndrome | Benign Familial Infantile Seizures | Thrombophlebitis | Pupil Disorders | Arteriosclerosis | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Vaginitis | Neural Tube Defect | Hypercalciuria | Joubert Syndrome 2 | Atrial Septal Defect | Glaucoma, Congenital | Porencephaly | Spinocerebellar Ataxia Type 38 | Genitopatellar Syndrome | Patent Foramen Ovale | Chronic Myelomonocytic Leukemia | Charcot-Marie-Tooth Disease Type 2D | Hypervalinemia | Long QT Syndrome Type 1 | Hemochromatosis Type 2 | Pyruvate Dehydrogenase Deficiency | Optic Neuritis | Blepharitis | Joubert Syndrome | Conn Syndrome | Sandhoff Disease | Cervical Dystonia | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | MELAS Syndrome | Neuroblastoma | Spinocerebellar Ataxia | Renal Tubular Acidosis | Diabetes | DICER1 Syndrome | Renal-hepatic-pancreatic Dysplasia | Silicosis | Autosomal Recessive Spastic Paraplegia Type 35 | Cheilitis | Filariasis | Aplasia Cutis Congenita | Arthropathy | Twin-to-twin Transfusion Syndrome | Polydactyly | Non-small Cell Lung Cancer | Contact Dermatitis | Granuloma Annulare | Costello Syndrome | Atelosteogenesis Type 1 | Cholesteryl Ester Storage Disease | Glioblastoma | Wagner Disease | Hyperparathyroidism | Tumoral Calcinosis | Okihiro Syndrome | Eclampsia | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Hyperinsulinism-hyperammonemia Syndrome | Glycogen Storage Disease Type 1b | Giant Cell Glioblastoma | Infertility | Chronic Granulomatous Disease | Congenital Poikiloderma | Nestor-Guillermo Progeria Syndrome | Fukuyama Congenital Muscular Dystrophy | Diabetes Type 2 | Blue Nevus | Lennox-Gastaut Syndrome | Porphyria | Ocular Hypertension | Ocular Surface Squamous Neoplasia | Gangliosidosis | Lipid Storage Diseases | Herpes Genitalis | Silver-Russell Syndrome | Metachromatic Leukodystrophy | Hyperacusis | Granular Corneal Dystrophy | Endometrial Hyperplasia | Varicocele | Smith-Lemli-Opitz Syndrome | Stargardt Disease | Jacobsen Syndrome | Waardenburg Syndrome Type 4A | Early Infantile Epileptic Encephalopathy 13 | Chediak-Higashi Syndrome | Pemphigoid | Tardive Dyskinesia | Coronary Heart Disease | Tuberculous Meningitis | Acute Chest Syndrome | Bronchitis | Corneal Dystrophy And Perceptive Deafness | Lissencephaly 2 | Larsen Syndrome | DiGeorge Syndrome | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Graves Disease | Sulfite Oxidase Deficiency | Scapuloperoneal Spinal Muscular Atrophy | Impulse Control Disorder | Vitamin B12 Deficiency | Nephrotic Syndrome | Microvillus Inclusion Disease | Basal Cell Nevus Syndrome | Dyslexia | Encephalitis, Tick-borne | Infantile Refsum Disease | Cancer, Lung | Hypertensive Nephropathy | Biotinidase Deficiency | Skin Papilloma | Alcoholism | Chronic Thromboembolic Pulmonary Hypertension | Ghosal Syndrome | Cardiomyopathy, Hypertrophic | Hypertensive Retinopathy | Carotid Artery Disease | Lymphangioma | Early Infantile Epileptic Encephalopathy | Cholestasis, Intrahepatic | Hypertension | Scleritis | Chronic Mucocutaneous Candidiasis | Waardenburg Syndrome Type 4 | Chronic Beryllium Disease | Spondylosis | Hidradenitis | Hyperparathyroidism, Primary | Hyperthermia, Malignant | Corneal Ulcer | Cerebellar Ataxia, Cayman Type | Intestinal Hypomagnesemia 1 | Gingivitis | Benign Familial Neonatal Convulsions | Huntington's Disease | Goiter | Orthostatic Intolerance | 3-methylglutaconic Aciduria Type IV | Cryoglobulinemia | Aromatic L-amino Acid Decarboxylase Deficiency | REM Sleep Behavior Disorder | Peters-plus Syndrome | Optic Neuropathy, Anterior Ischemic | Occipital Neuralgia | Leukoplakia, Oral | Muckle-Wells Syndrome | Granular Corneal Dystrophy Type 1 | Dyskeratosis Congenita | Osteomyelitis | Spinocerebellar Ataxia Type 5 | Sponastrime Dysplasia | Generalized Epilepsy And Paroxysmal Dyskinesia | Syphilis | Nager Acrofacial Dysostosis | Spinocerebellar Ataxia Type 13 | Sialidosis Type I | Sleep Apnea, Central | Cancer, Prostate | Bronchiolitis | Guillain-Barre Syndrome | Antithrombin III Deficiency | Progressive Osseous Heteroplasia | Progressive Familial Intrahepatic Cholestasis Type 3 | Diabetic Encephalopathy | Dominant Optic Atrophy | Nephronophthisis | Hereditary Hemorrhagic Telangiectasia | Cystitis | Anti-glomerular Basement Membrane Disease | Juvenile Xanthogranuloma | Familial Mediterranean Fever | Cardiac Sarcoidosis | Dental Caries | Autoimmune Polyendocrinopathy Syndrome Type I | Tyrosinemia | Pseudohypoparathyroidism Type 1B | Cyclic Vomiting Syndrome | Panuveitis | Meleda Disease | Spinocerebellar Ataxia Type 15 | Cold Agglutinin Disease | Dent Disease | Porphyria Cutanea Tarda | Hyperbilirubinemia | Cardiospondylocarpofacial Syndrome | Pearson Syndrome | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Hypersomnia | Mitochondrial DNA Depletion Syndrome, Myopathic Form