Porencephaly

About the Disease
Porencephaly is related to familial porencephaly and brain small vessel disease 2. An important gene associated with Porencephaly is COL4A1 (Collagen Type IV Alpha 1 Chain), and among its related pathways/superpathways are ERK Signaling and Integrin Pathway. The drug Thrombin has been mentioned in the context of this disorder. Affiliated tissues include brain, temporal lobe and fetal brain, and related phenotypes are spasticity and ventriculomegaly

Common Targets
COL4A1 | COL4A2

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