Hyper IgE Syndrome

About the Disease
Hyper Ige Syndrome, also known as hyper-ige syndrome, is related to hyper-ige recurrent infection syndrome 1, autosomal dominant and immunodeficiency 35, and has symptoms including seizures An important gene associated with Hyper Ige Syndrome is STAT3 (Signal Transducer And Activator Of Transcription 3), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Miconazole and Posaconazole have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and bone, and related phenotypes are homeostasis/metabolism and immune system

Common Targets
Immunoglobulin E (IgE) | G6774 | DOCK8 | PGM3 | IL6ST

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