Thin Basement Membrane Disease

About the Disease
Hematuria, Benign Familial, also known as benign familial hematuria, is related to alport syndrome 2, autosomal recessive and alport syndrome 3, autosomal dominant. An important gene associated with Hematuria, Benign Familial is COL4A4 (Collagen Type IV Alpha 4 Chain), and among its related pathways/superpathways are Integrin Pathway and Phospholipase-C Pathway. The drugs Enalaprilat and Enalapril have been mentioned in the context of this disorder. Affiliated tissues include kidney, myeloid and liver, and related phenotypes are hematuria and thin glomerular basement membrane

Common Targets
FAT2 | KIRREL2 | COL4A3 | COL4A4

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