Disease

Lymphedema

About the Disease
Hereditary Lymphedema I, also known as lymphedema, is related to lymphatic malformation 1 and cholestasis-lymphedema syndrome, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Hereditary Lymphedema I is FLT4 (Fms Related Receptor Tyrosine Kinase 4), and among its related pathways/superpathways are Phospholipase-C Pathway and p70S6K Signaling. The drugs Bupivacaine and Tocopherol have been mentioned in the context of this disorder. Affiliated tissues include Heart, lymph node and breast, and related phenotypes are no effect and no effect

Common Targets
KDR | G4318 | G7124 | G23411 | CCBE1 | Inhibitor of Apoptosis Proteins (IAPs) (nonspecified subtype) | XDH | SYK | VEGFC | Steroid 5-alpha-Reductase (nonspecified subtype) | ANGPT2 | EPHB4 | VCAM1 | NF-kappaB (NFkB) | MIER2 | PIEZO1 | PDGFRA | GATA2 | NRP2 | KIT | CELSR1 | LCP2 | G3576 | ITFG1 | HLA-DQB1 | GJC2 | MDFIC | ACE | PDGFRB | FOXC2 | LTA4H | ANPEP | G3569 | FLT1 | FLT4

疾病靶点研报
Lymphedema

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