CHARGE Syndrome

About the Disease
Charge Syndrome, also known as charge association, is related to choanal atresia, posterior and coloboma of macula. An important gene associated with Charge Syndrome is CHD7 (Chromodomain Helicase DNA Binding Protein 7), and among its related pathways/superpathways are Signal Transduction and Chromatin Regulation / Acetylation. Affiliated tissues include heart, eye and retina, and related phenotypes are hearing impairment and global developmental delay

Common Targets
PUF60 | RERE | CHD7 | G2033 | CDH7 | KMT2D | SEMA3A | USP9X | KDM6A

Note: If you'd like to get a target analysis report for CHARGE Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of CHARGE Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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