Disease

Hypereosinophilic Syndrome

About the Disease
Hypereosinophilic Syndrome, also known as eosinophilia, is related to hypereosinophilic syndrome, idiopathic and primary hypereosinophilic syndrome, and has symptoms including pruritus, myalgia and abdominal pain. An important gene associated with Hypereosinophilic Syndrome is FIP1L1 (Factor Interacting With PAPOLA And CPSF1), and among its related pathways/superpathways are Innate Immune System and Signal Transduction. The drugs Prednisone and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, heart and bone, and related phenotypes are Decreased viability and Decreased viability

Common Targets
BCR | AQP12B | PUF60 | SYK | LMLN | Tyrosine Kinase (nonspecified subtype) | PDGFRA | CDH17 | JAK2 | KIT | JAK1 | JAK3 | PTGDR2 | IL5 | ABL1 | PDGFRB | IL5RA | CSF1R | OPRM1 | HLA-B | TYK2 | PCSK1

疾病靶点研报
Hypereosinophilic Syndrome

Note: If you'd like to get a target analysis report for Hypereosinophilic Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hypereosinophilic Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Craniometaphyseal Dysplasia | GNE Myopathy | Vertebrobasilar Insufficiency | Prostatitis | Rheumatic Heart Disease | Blood Protein Disorders | Antiphospholipid Syndrome | Heterotaxy | Spinocerebellar Ataxia Type 38 | Hepatitis A | Tangier Disease | Chordoma | Vaginitis | Hyperprolactinemia | Hyperuricemic Nephropathy, Familial Juvenile | Gliosarcoma | Leber Hereditary Optic Neuropathy | Leber Congenital Amaurosis | Tietze Syndrome | Charcot-Marie-Tooth Disease, Type 6 | Sarcoma, Alveolar Soft Part | Huntington's Disease-like 2 | Nephrosclerosis | Mitochondrial DNA Depletion Syndrome | Osteogenesis Imperfecta | Neurofibroma | Anti-NMDA Receptor Encephalitis | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Cancer, Breast | Spastic Paraplegia Type 7 | Aphasia | Wolman Disease | B-cell Prolymphocytic Leukemia | Cold Agglutinin Disease | Microcephaly | Pseudohypoparathyroidism Type 1C | Mitochondrial Myopathy | Fanconi Anemia | Idiopathic Multicentric Castleman Disease | Neurofibromatosis Type 2 | Anterior Segment Dysgenesis | Hereditary Neuropathy With Liability To Pressure Palsies | Juvenile Polyposis | Proteus Syndrome | Meningococcal Meningitis | Neurofibrosarcoma | Fragile X Syndrome | Congenital Dyserythropoietic Anemia Type 4 | Rothmund-Thomson Syndrome | Hemochromatosis Type 1 | Fetal Alcohol Syndrome | Nicotine Dependence | Amenorrhea | Ameloblastoma | Gynecomastia | Nemaline Myopathy 10 | Pure Red Cell Aplasia | Ataxia-ocular Apraxia 2 | Major Depression | Vascular Calcification | Schizencephaly | Kashin-Beck Disease | Sickle Cell Disease | Borderline Personality Disorder | Familial Advanced Sleep Phase Syndrome | Acute Kidney Injury | Peripheral T-cell Lymphoma | Diabetes | Hypertensive Nephropathy | Paraplegia | Epithelial-myoepithelial Carcinoma | Gingivitis | Myositis | Adenomatoid Tumor | Sengers Syndrome | Demyelinating Diseases | Asthma, Exercise-induced | 3-methylglutaconic Aciduria Type I | Thin Basement Membrane Disease | Epithelioid Hemangioma | Tonsillitis | Hepatitis B, Chronic | Tracheal Disorders | Achromatopsia | Chronic Periodontitis | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Acute Anterior Uveitis | Charcot-Marie-Tooth Disease Type 3 | Myositis, Focal | Hypertension, Portal | Metaphyseal Chondrodysplasia, Schmid Type | Cellulitis | Gray Platelet Syndrome | Syndactyly | Jacobsen Syndrome | Astrocytoma, Anaplastic | Pseudomyxoma Peritonei | Thyroid Dysgenesis | Choroideremia | Spinocerebellar Ataxia Type 17 | Varicocele | Diarrhea | Protein C Deficiency | Schaaf-Yang Syndrome | Paracoccidioidomycosis | Salla Disease | Coronary Heart Disease | Psoriasis | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Sensorineural Hearing Loss | Vascular Cognitive Impairment | Trigonocephaly | T-cell Chronic Lymphocytic Leukemia | Rickets | Disseminated Intravascular Coagulation | Chromosome 16p11.2 Deletion Syndrome | Central Retinal Artery Occlusion | Li-Fraumeni Syndrome | Glycogen Storage Disease Type 0, Muscle | Hypotension, Orthostatic | Cancer, Kidney | Oculocutaneous Albinism Type 2 | Oculocutaneous Albinism | Ectodermal Dysplasia | Tremor | Palmoplantar Keratoderma | Epicondylitis | Obsessive-compulsive Disorder | Cat Eye Syndrome | Cole-Carpenter Syndrome | Wilson's Disease | Strabismus | Alpha-mannosidosis | Astigmatism | Pulmonary Alveolar Proteinosis | Stiff-man Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Gerstmann-Straussler-Scheinker Syndrome | Goiter, Nodular | Nephrocalcinosis | Filariasis | CDKL5 Deficiency Disorder | Cabezas Syndrome | Chromosome 9q34.3 Deletion Syndrome | 3-methylcrotonyl-CoA Carboxylase Deficiency | Pituitary Dwarfism | Left Ventricular Noncompaction | Hyperekplexia | Spinocerebellar Ataxia Type 42 | Tyrosinemia | Blastomycosis | Graft-versus-host Disease | Anuria | Polycystic Kidney, Autosomal Dominant | Sialidosis | Non-proliferative Diabetic Retinopathy | Specific Granule Deficiency | Familial Pheochromocytoma-paraganglioma | Primary Erythromelalgia | Gastric Atrophy | Malaria | Spermatocele | Cardiofaciocutaneous Syndrome | Trimethylaminuria | Chronic Lymphocytic Leukemia | Sarcoidosis, Pulmonary | Aplastic Anemia | Disseminated Superficial Actinic Porokeratosis | Tay-Sachs Disease | Sarcomatoid Carcinoma Of The Lung | Endometrial Hyperplasia | Autosomal Recessive Congenital Ichthyosis | Megaloblastic Anemia | Gerodermia Osteodysplastica | Anovulation | Enlarged Vestibular Aqueduct | Pulmonary Stenosis | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Ellis-Van Creveld Syndrome | Hidradenitis Suppurativa | Chronic Leukemia | Shock, Cardiogenic | Cardiomyopathy, Restrictive | Alkaptonuria | Hairy Cell Leukemia | Lipid Metabolism Disorders | Sarcoma, Ewing | Chronic Thromboembolic Pulmonary Hypertension | Echinococcosis | Hemolytic Anemia | Leiomyosarcoma | Primary Familial Brain Calcification | Eosinophilic Asthma | Peritonitis | Hemophilia | Viral Meningitis | Liddle Syndrome | Lymphoma Lymphoblastic | Nasodigitoacoustic Syndrome | Hereditary Hemorrhagic Telangiectasia | Barrett Esophagus | Macular Degeneration | B-cell Chronic Lymphocytic Leukemia | Restless Legs Syndrome | Congenital Torticollis | Cluster Headache | Neuromyelitis Optica | Lissencephaly 2 | Dysthymia | Photosensitivity | Arrhythmogenic Right Ventricular Cardiomyopathy | Waardenburg Syndrome Type 2E | Colitis, Microscopic | Tardive Dyskinesia | Hereditary Sensory Neuropathy Type 1 | Multicentric Carpotarsal Osteolysis Syndrome | Dementia | Basan Syndrome | Cyst | Malignant Peripheral Nerve Sheath Tumor | Malignant Fibrous Histiocytoma | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | GAPO Syndrome | Swine Influenza | Presbyopia | Pseudohypoparathyroidism Type 1B | Corneal Dystrophies, Hereditary | Retinal Degeneration | Endophthalmitis | Mosaic Variegated Aneuploidy Syndrome 2 | Costello Syndrome | Addison Disease | Parvovirus B19 Infection | Richter's Syndrome | Glycogen Storage Disease Type 1 | Pulmonary Capillary Hemangiomatosis | Preaxial Polydactyly | Nephropathy | Fraser Syndrome | Atelosteogenesis Type 1 | Alopecia Totalis | Angelman Syndrome | Unverricht-Lundborg Syndrome | Tuberculosis | NGLY1 Deficiency | Globozoospermia | Carcinoma, Small Cell | Thymoma, Malignant | Acral Lentiginous Melanoma | Familial Hyperaldosteronism | Erythromelalgia | Sclerocornea | Takotsubo Cardiomyopathy | Restrictive Dermopathy | Autonomic Neuropathy | Bone Marrow Necrosis | Desmosterolosis | Hemimegalencephaly | Hemangioblastoma | Osteogenesis Imperfecta Type VI | Cervicitis | Distal Myopathy | Glanzmann Thrombasthenia | Cone Dystrophy | Bacterial Meningitis | Goiter | Lymphangiomatosis | Osteochondroma | Peutz-Jeghers Syndrome | Lichen Planus | Arteriosclerosis | Chylothorax, Congenital | Phenylketonuria | Sleep Apnea | Ulcerative Colitis | Transthyretin-related Amyloidosis | Schwartz-Jampel-Aberfeld Syndrome | Usher Syndrome Type III | Gestational Trophoblastic Disease | Corneal Dystrophy And Perceptive Deafness | Precocious Puberty | Protein S Deficiency | Cri-du-chat Syndrome | Retinopathy Of Prematurity | Trichorhinophalangeal Syndrome | Adenoma, Pituitary | Antley-Bixler Syndrome | Down Syndrome | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Still Disease | Glycogen Storage Disease Type 9 | Scleroderma, Diffuse | Myelitis, Transverse | Craniolenticulosutural Dysplasia | Encephalopathy, Hepatic | Neuroleptic Malignant Syndrome | Urethritis | Premenstrual Syndrome | Brachydactyly | Fibromyalgia | Juvenile Xanthogranuloma | Subcortical Band Heterotopia | Galactosemia | Panuveitis | Anthrax | Periventricular Nodular Heterotopia | Hypotrichosis | Congenital Adrenal Hyperplasia | Adenylosuccinate Lyase Deficiency | Trismus-pseudocamptodactyly Syndrome | Pneumococcal Meningitis | Opisthorchiasis | Amish Infantile Epilepsy Syndrome | Infantile Neuroaxonal Dystrophy | Hypospadias | Kabuki Syndrome | Multiple Sclerosis | Hereditary Inclusion Body Myopathy | Early Infantile Epileptic Encephalopathy 13 | Coenzyme Q10 Deficiency | Spinocerebellar Ataxia Type 27 | Walker-Warburg Syndrome | Neuroendocrine Cancer | Carotid Artery Disease | ACTH-independent Macronodular Adrenal Hyperplasia | Glycogen Storage Disease Type 0 | Tyrosinemia Type 1 | Brenner Tumor | Cancer, Skin | Mitochondrial Cytopathy | Hemorrhagic Disorders | Hypereosinophilic Syndrome | Greig Cephalopolysyndactyly Syndrome | Pierpont Syndrome | Cervical Dystonia | Polyneuropathy | DOCK8 Immunodeficiency Syndrome | Congestive Heart Failure | Brugada Syndrome 1 | Leukodystrophies | Schizoaffective Disorder | Mannosidase Deficiency Diseases | Myelofibrosis | Duodenal Atresia | Encephalocele | Inflammatory Joint Disease | Conn Syndrome | Meesmann Corneal Dystrophy | Primary Carnitine Deficiency | Carbonic Anhydrase VA Deficiency | Speech Disorders | Hyperhomocysteinemia | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Patent Ductus Arteriosus | Osteonecrosis | Congenital Heart Defects | Trichotillomania | Sporadic Hemiplegic Migraine | Non-Langerhans Cell Histiocytosis | Kernicterus | Zimmermann-Laband Syndrome | Placenta Previa | Epidermolytic Hyperkeratosis | Wolfram Syndrome 2 | Aarskog-Scott Syndrome | Van Der Knaap Disease | Hodgkin Lymphoma | Myoclonic Atonic Epilepsy | Familial Dysautonomia | Pulmonary Vein Stenosis | Bronchiectasis | Progressive Familial Intrahepatic Cholestasis Type 2 | Glutaric Aciduria Type 1 | Joubert Syndrome | Hereditary Elliptocytosis | Congenital Stromal Corneal Dystrophy | Encephalopathy | Sick Sinus Syndrome | Wagner Disease | Non-epidermolytic Palmoplantar Keratoderma | Glutathione Synthetase Deficiency | Leukoencephalopathy, Progressive Multifocal | Cholangitis | Atopic Dermatitis | Schnyder Crystalline Corneal Dystrophy | Paronychia | Bethlem Myopathy | Corneal Dystrophy | Dental Caries | Retinoblastoma | Analgesia | ADNP Syndrome | Cystinosis | Systemic Lupus Erythematosus | Hypohidrotic Ectodermal Dysplasia, X-linked | Heterotopic Ossification | GM2-gangliosidosis AB Variant | Guanidinoacetate Methyltransferase Deficiency | Hereditary Pyropoikilocytosis | Von Hippel-Lindau Disease