Autosomal Recessive Early-onset Parkinson Disease 6

About the Disease
Parkinson Disease 6, Autosomal Recessive Early-Onset, also known as autosomal recessive early-onset parkinson disease 6, is related to parkinson disease 2, autosomal recessive juvenile and parkinsonism, and has symptoms including muscle rigidity, bradykinesia and resting tremor. An important gene associated with Parkinson Disease 6, Autosomal Recessive Early-Onset is PINK1 (PTEN Induced Kinase 1), and among its related pathways/superpathways are Parkinson's disease pathway and Alpha-synuclein signaling. Affiliated tissues include brain, cortex and subthalamic nucleus, and related phenotypes are hyperreflexia and anxiety

Common Targets
PINK1

Note: If you'd like to get a target analysis report for Autosomal Recessive Early-onset Parkinson Disease 6, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Autosomal Recessive Early-onset Parkinson Disease 6 at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Persistent Hyperplastic Primary Vitreous | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Parvovirus B19 Infection | Dental Caries | Beta-Propeller Protein-associated Neurodegeneration | IgA Nephropathy | Spinocerebellar Ataxia Type 12 | Proteasome-associated Autoinflammatory Syndrome 2 | Aicardi-Goutieres Syndrome | Neurofibromatosis Type 1 | Erythema Multiforme | Hereditary Hemorrhagic Telangiectasia | Iron Deficiency Anemia | Sick Sinus Syndrome 1 | Mohr-Tranebjaerg Syndrome | KBG Syndrome | Sengers Syndrome | Tangier Disease | Leukodystrophies | Hypodontia | Familial Retinal Arterial Macroaneurysm | Macrophagic Myofasciitis | Language Disorders | Pulmonary Vein Stenosis | Chudley-McCullough Syndrome | Gallstones | Leukocyte Adhesion Deficiency | Trichotillomania | Onchocerciasis | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Binge Eating Disorder | Nephritis, Interstitial | Myoclonic Epilepsy With Ragged Red Fibers | Antiphospholipid Syndrome | Acute Lymphocytic Leukemia | Periventricular Nodular Heterotopia | Hyperekplexia | Rubeosis Iridis | Ameloblastic Carcinoma | Botulism | Chromosome 8q21.11 Deletion Syndrome | Osteomalacia | Castleman Disease | Keratoconus | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Hyperphenylalaninemia | Cholesteryl Ester Storage Disease | Seasonal Mood Disorder | Lyme Disease | Presbyopia | Diabetic Macular Edema | Spinocerebellar Ataxia Type 31 | Veno-occlusive Disease | Neuroma | GNE Myopathy | GM2-gangliosidosis AB Variant | Liver Failure, Acute Infantile | Spinocerebellar Ataxia Type 16 | Pleomorphic Xanthoastrocytoma | Agranulocytosis | Hepatitis A | Urolithiasis | Pheochromocytoma | Danon Disease | Angioedema, Hereditary | Intermittent Explosive Disorder | Arteriosclerosis | Panic Disorder | Hepatitis, Autoimmune | Autosomal Recessive Spastic Paraplegia Type 35 | Pontocerebellar Hypoplasia | Weill-Marchesani Syndrome | Pseudohypoparathyroidism Type 1B | ICF Syndrome | Retinal Dystrophy, Early-onset Severe | Neurocutaneous Syndromes | Myoclonic Atonic Epilepsy | Hyperlipidemia, Familial Combined | Angiodysplasia | Hereditary Xerocytosis | Chitayat Syndrome | Infantile Nephropathic Cystinosis | Fontaine Progeroid Syndrome | Avellino Corneal Dystrophy | Hypotrichosis | 3-methylglutaconic Aciduria | Acromicric Dysplasia | Still Disease | Hyperinsulinemia | Metanephric Adenoma | Ganglioneuroma | Best Macular Dystrophy | Cat Eye Syndrome | Episodic Ataxia | PHARC Syndrome | Crigler-Najjar Syndrome | Leprosy | Glioblastoma Multiforme | Hereditary Inclusion Body Myopathy | Neuroectodermal Tumors, Primitive | Cornelia De Lange Syndrome | Hereditary Spastic Paraplegia | Schizophrenia, Paranoid | Encephalocele | Knobloch Syndrome | Hypospadias | HELLP Syndrome | Autoimmune Disease | Adenoid Cystic Carcinoma | Histiocytic Sarcoma | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Mosaic Variegated Aneuploidy Syndrome 2 | Methylmalonic Acidemia | Brenner Tumor | Holoprosencephaly | Familial Isolated Hyperparathyroidism | Multiple Myeloma | Neurofibromatosis-Noonan Syndrome | Heterotopic Ossification | Myosin Storage Myopathy | Esophagitis, Eosinophilic | Cryptorchidism | Atrioventricular Septal Defect | Myoclonus-dystonia Syndrome | Inflammatory Myopathy | Lymphangiomatosis | Cancer, Skin | Chronic Inflammatory Demyelinating Polyneuropathy | Lymphoma, Follicular | Diabetes Insipidus | Benign Familial Infantile Seizures | Schwannoma | Cutis Laxa | Mumps | Neonatal Progeroid Syndrome | Angina Pectoris | Keratosis, Seborrheic | Rotor Syndrome | Alpha-1 Antitrypsin Deficiency | Succinic Semialdehyde Dehydrogenase Deficiency | Niemann-Pick Disease | Hennekam Lymphangiectasia-lymphedema Syndrome | Odonto-onycho-dermal Dysplasia | Congenital Dyserythropoietic Anemia Type 4 | Postaxial Polydactyly | Acute Lung Injury | Trichothiodystrophy | Hodgkin Lymphoma | Autonomic Nervous System Disorders | Adenoma, Pituitary | Ehlers-Danlos Syndrome | Lymphoma, Mantle Cell | Supravalvular Aortic Stenosis | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Charcot-Marie-Tooth Disease Type 4D | Encephalopathy, Hepatic | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Hepatitis E | Familial Hypertrophic Cardiomyopathy | Tibial Muscular Dystrophy | Amyloidosis | Chromosome 16p11.2 Deletion Syndrome | Chylothorax, Congenital | Acute Motor Axonal Neuropathy | Macular Corneal Dystrophy | Osteosclerosis | Thyroid Hormone Resistance | ADNP Syndrome | Azoospermia | Oligoastrocytoma | Primary Progressive Nonfluent Aphasia | C3 Glomerulopathy | Asperger Syndrome | Cardiomyopathy, Hypertrophic | Crisponi Syndrome | Myoclonus | Herpes Genitalis | Cherubism | Lupus Erythematosus | Rheumatoid Arthritis | Aneurysm, Thoracic Aortic | Central Core Disease | Cerebrotendinous Xanthomatosis | Hypohidrotic Ectodermal Dysplasia, X-linked | Hydrocephalus, Normal Pressure | Myelofibrosis | Cone Dystrophy | Kabuki Syndrome 2 | Discoid Lupus Erythematosus | Hemangioblastoma | Pupil Disorders | Microcephaly, Seizures, And Developmental Delay | Stuve-Wiedemann Syndrome | Pyruvate Dehydrogenase Deficiency | Congenital Fiber-type Disproportion Myopathy | Peyronie's Disease | Van Der Knaap Disease | DOCK8 Immunodeficiency Syndrome | Hyperuricemia | Diarrhea | Platelet Disorders | Tremor | Homocystinuria | Blepharospasm | Pseudomyxoma Peritonei | Androgen Insensitivity | Absence Epilepsy | Agoraphobia | Narcolepsy | Enhanced S-cone Syndrome | Yellow Fever | Eosinophilic Asthma | Lymphoma, AIDS-related | DICER1 Syndrome | Kawasaki Disease | Anti-NMDA Receptor Encephalitis | Renal Tubular Acidosis | Amelogenesis Imperfecta | Mixed Connective Tissue Disease | Campomelic Dysplasia | CHOPS Syndrome | HANAC Syndrome | Joubert Syndrome | Bronchiolitis | Uremic Pruritus | Leukocyte Adhesion Deficiency Type 1 | Wiskott-Aldrich Syndrome | Neurocutaneous Melanocytosis | Erdheim-Chester Disease | Wieacker-Wolff Syndrome | Retinal Telangiectasia | Cryopyrin-associated Periodic Syndromes | Nail-Patella Syndrome | Melanoma, Malignant | Dystonia Musculorum Deformans | Hemochromatosis Type 1 | Diffuse Palmoplantar Keratoderma | Ornithine Transcarbamylase Deficiency | Pelizaeus-Merzbacher Disease | Hydrocephalus | Fibromuscular Dysplasia | Pemphigus Foliaceus | Dyslexia | Epithelioid Hemangioma | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Protein S Deficiency | Methemoglobinemia Type IV | Chordoid Glioma | Anorexia Nervosa | Inflammatory Bowel Disease | Chloridorrhea, Congenital | Melanoma, Uveal | Hypothyroidism | Ocular Albinism Type 1 | Creatine Deficiency Syndrome | Anorectal Malformations | Agammaglobulinemia | Glycogen Storage Disease Type 5 | Globozoospermia | Sarcoidosis | Multiple Sulfatase Deficiency | Creutzfeldt-Jakob Disease | Pontocerebellar Hypoplasia Type 2 | Spondyloperipheral Dysplasia | Camurati-Engelmann Disease | Osteoporosis, Postmenopausal | Pitt-Hopkins Syndrome | Adenosine Deaminase Deficiency | Stargardt Disease | Acrodermatitis Enteropathica | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Muckle-Wells Syndrome | Coffin-Siris Syndrome | Postpartum Depression | Microcephalic Primordial Dwarfism | Mucolipidosis | Graft-versus-host Disease | Williams Syndrome | Familial Glucocorticoid Deficiency | AIDS | Hyperparathyroidism, Primary | Systemic Lupus Erythematosus | Hyperkeratosis | Gangliosidosis, GM1 | Giant Cell Arteritis | Panuveitis | Hydronephrosis | Osteoarthritis | Fascioliasis | Hypervalinemia | Renal Dysplasia | Angiosarcoma Of The Breast | Thanatophoric Dysplasia Type 1 | Diabetes Insipidus, Neurogenic | Neurotoxicity | Rift Valley Fever | Dowling-Degos Disease | LMNA-related Congenital Muscular Dystrophy | Gastritis | Sweet Syndrome | Costello Syndrome | Acute Chest Syndrome | Cervical Dystonia | Recurrent Respiratory Papillomatosis | Primary Sclerosing Cholangitis | Cerebrovascular Disorders | Optic Neuritis | Lassa Fever | Asplenia | Osteogenesis Imperfecta Type III | Brachydactyly | Waardenburg Syndrome Type 2E | Cardiac Arrest | Congenital Absence Of Vas Deferens | Lichen Sclerosus | Anovulation | Metabolic Syndrome | Early Infantile Epileptic Encephalopathy 1 | Pleural Tuberculosis | Alstrom Syndrome | Chromosome 9q34.3 Deletion Syndrome | Pycnodysostosis | Chronic Myelomonocytic Leukemia | Congenital Adrenal Hyperplasia 1 | Leishmaniasis, Visceral | Infantile Refsum Disease | Thyroiditis, Autoimmune | Schnitzler Syndrome | Familial Partial Lipodystrophy | Apparent Mineralocorticoid Excess Syndrome | Fuchs Dystrophy | Hypertension, Renal | Hypersensitivity | Spinocerebellar Ataxia Type 2 | Adenocarcinoma | Nephrosclerosis | Ebstein Anomaly | Hepatitis, Alcoholic | Hypobetalipoproteinemias | Gastritis, Atrophic | Leukoplakia, Oral | Idiopathic Multicentric Castleman Disease | Acrocallosal Syndrome | Acute Anterior Uveitis | Disseminated Intravascular Coagulation | Cancer, Breast | Cysticercosis | Macrodactyly | Phenylketonuria II | Gyrate Atrophy Of The Choroid And Retina | Pneumonia, Viral | Hereditary Sensory Neuropathy Type 1 | Carcinoma, Squamous Cell | Nail Disorder, Nonsyndromic Congenital | Ollier Disease | Leri Pleonosteosis | Angelman Syndrome | Chorioretinitis | Proximal Symphalangism | Hyperparathyroidism-jaw Tumor Syndrome | Congenital Adrenal Hyperplasia | Meningitis | Seizures | Beare-Stevenson Syndrome | Syphilis | Crohn's Disease | Noonan Syndrome | Anodontia | Empyema | Dysfibrinogenemia | Tetraplegia | Hemangioma | Carcinoma, Signet Ring Cell | Progressive Encephalopathy-optic Atrophy Syndrome | Pleurisy | Giant Cell Glioblastoma | Early Infantile Epileptic Encephalopathy 13 | Loeys-Dietz Syndrome | Xeroderma Pigmentosum | Parkinson's Disease | Keloid | Pseudohypoaldosteronism | Toxoplasmosis | Gardner Syndrome | Reticular Dysgenesis | Alpha-mannosidosis | Mevalonate Kinase Deficiency | Bainbridge-Ropers Syndrome | Tetanus | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Retinal Detachment | Feingold Syndrome | Inflammatory Linear Verrucous Epidermal Nevus | Osteoporosis | Niemann-Pick Disease, Type A | Raine Syndrome | Oculocutaneous Albinism Type 1 | Leri-Weill Dyschondrosteosis | Cholestasis, Intrahepatic | Congenital Stromal Corneal Dystrophy