Tetraplegia

About the Disease
Quadriplegia, also known as tetraplegia, is related to leukodystrophy, hypomyelinating, 6 and pelizaeus-merzbacher disease, and has symptoms including hemiplegia, ophthalmoplegia and muscle weakness. An important gene associated with Quadriplegia is ELOVL4 (ELOVL Fatty Acid Elongase 4), and among its related pathways/superpathways is "Oligodendrocyte specification and differentiation, leading to myelin components for CNS". The drugs Benzocaine and Tannic acid have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and tongue, and related phenotypes are no effect and no effect

Common Targets
AP4B1 | KCNMA1 | AP4M1 | G6647

Note: If you'd like to get a target analysis report for Tetraplegia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Tetraplegia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

DICER1 Syndrome | Lipid Metabolism Disorders | Epithelial-myoepithelial Carcinoma | Pseudohypoaldosteronism | Carbonic Anhydrase VA Deficiency | Cancer, Breast | Von Hippel-Lindau Disease | Fowler's Syndrome | Hypothyroidism | Lymphedema-distichiasis Syndrome | Sarcoidosis, Pulmonary | D-2-Hydroxyglutaric Aciduria | Vulvovaginitis | Snyder-Robinson Syndrome | Asphyxia Neonatorum | Isovaleric Acidemia | Basal Ganglia Disease | Cataplexy | Tularemia | Coffin-Siris Syndrome | Aneurysm, Thoracic Aortic | Polycythemia | Wieacker-Wolff Syndrome | Papulopustular Rosacea | Cardiomyopathy, Hypertrophic | Corneal Neovascularization | Kawasaki Disease | Rheumatoid Arthritis | Gangliosidosis | Encephalopathy | Common Cold | Pituitary Disorders | Splenomegaly | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Congenital Adrenal Hyperplasia | Gardner Syndrome | Congenital Poikiloderma | Relapsing Polychondritis | Diabetic Encephalopathy | Stroke, Ischemic | Azoospermia | Lymphedema | Nance-Horan Syndrome | Lichen Sclerosus | Rett Syndrome | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Spinocerebellar Ataxia Type 10 | HUPRA Syndrome | Asplenia | Persistent Mullerian Duct Syndrome | B-cell Chronic Lymphocytic Leukemia | Pupil Disorders | Migraine | Hereditary Folate Malabsorption | Hyperinsulinemic Hypoglycemia | Malignant Peripheral Nerve Sheath Tumor | Myeloid Leukemia | Angelman Syndrome | DiGeorge Syndrome | Pneumonia, Viral | Cocaine-Related Disorders | Pulmonary Vein Stenosis | Glanzmann Thrombasthenia | Atelosteogenesis Type 2 | Mucolipidosis Type III | Panniculitis | Multiple Sclerosis, Secondary Progressive | Aspergillosis | Acute Myeloid Leukemia | Anal Fissure | Carcinoma In Situ | Dysthymia | Pierre Robin Syndrome | Van Der Knaap Disease | Low Phospholipid Associated Cholelithiasis | Hypobetalipoproteinemias | Adenoid Cystic Carcinoma | Rubinstein-Taybi Syndrome | Focal Dermal Hypoplasia | Tricho-hepato-enteric Syndrome | Werner's Syndrome | Granular Corneal Dystrophy | Hereditary Sensory Neuropathy Type 1 | Stroke | Gingivitis | Mesothelioma, Malignant | Alopecia Areata | Cystinosis | Chronic Kidney Disease | Carney Triad | Insulin Resistance | Chorioretinitis | Greig Cephalopolysyndactyly Syndrome | Postaxial Polydactyly | Progressive Familial Intrahepatic Cholestasis Type 3 | Hypopituitarism | Bainbridge-Ropers Syndrome | Focal Facial Dermal Dysplasia | Arthropathy | Cole-Carpenter Syndrome | Mucolipidosis Type II | Hyperkalemic Periodic Paralysis | Yellow Fever | Tyrosinemia | Oculocutaneous Albinism Type 4 | Williams Syndrome | Sleep Apnea, Central | Barrett Esophagus | Adenoma, Pituitary | Hepatic Adenomatosis | Multisystemic Smooth Muscle Dysfunction Syndrome | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Peyronie's Disease | Lymphangioleiomyomatosis | Achromatopsia | Salla Disease | Neuroendocrine Cancer | Methemoglobinemia Type IV | Diverticulitis | Bronchitis | Ectopia Lentis, Isolated, Autosomal Recessive | Addison Disease | Hypercalcemia | Familial Glucocorticoid Deficiency | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Endocarditis | Hypertelorism | Intracerebral Hemorrhage | Hyperferritinemia-cataract Syndrome | Intestinal Tuberculosis | Johanson-Blizzard Syndrome | Familial Retinal Arterial Macroaneurysm | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Schizophrenia | Usher Syndrome Type III | Cleidocranial Dysplasia | Polycystic Kidney, Autosomal Dominant | Paroxysmal Kinesigenic Dyskinesia | Woodhouse-Sakati Syndrome | Anorexia Nervosa | Chondrodysplasia Punctata | Cone Dystrophy | Patent Foramen Ovale | Platelet Disorders | Non-proliferative Diabetic Retinopathy | Scleroderma | Herpes Genitalis | Charcot-Marie-Tooth Disease, Type 2 | Granular Corneal Dystrophy Type 1 | Tibial Muscular Dystrophy | Pycnodysostosis | Sepiapterin Reductase Deficiency | Peripheral Neuropathy | Angiodysplasia | Malaria, Cerebral | Tyrosinemia Type 2 | Bulimia Nervosa | Spinal And Bulbar Muscular Atrophy | Wolcott-Rallison Syndrome | Eating Disorder | Mastitis | Carpenter Syndrome | Diabetes Mellitus, Transient Neonatal | Trismus-pseudocamptodactyly Syndrome | Tremor | Dupuytren Disease | Pterygium | Rhinitis | Aarskog-Scott Syndrome | Otitis Media | Paroxysmal Nocturnal Hemoglobinuria | Galloway-Mowat Syndrome | Dysmorphophobia | Metanephric Adenoma | Dyggve-Melchior-Clausen Disease | Multiple Myeloma | Pneumothorax | Allan-Herndon-Dudley Syndrome | Cardiac Sarcoidosis | Charcot-Marie-Tooth Disease Type 3 | Frank-ter Haar Syndrome | Postpoliomyelitis Syndrome | Congenital Ichthyosiform Erythroderma | Conjunctivitis, Allergic | Congenital Generalized Lipodystrophy | Nasodigitoacoustic Syndrome | Dyslexia | Familial Digital Arthropathy-brachydactyly | Varices | Neurofibromatosis | Macular Degeneration | Nicotine Dependence | Cerebral Cavernous Malformations | Methylmalonic Aciduria And Homocystinuria, CblC Type | Corneal Dystrophy And Perceptive Deafness | Cherubism | Neutropenia | Pantothenate Kinase-associated Neurodegeneration | Axenfeld-Rieger Syndrome | Dermatitis | Demyelinating Diseases | Glaucoma, Congenital | Cardiospondylocarpofacial Syndrome | Metachromatic Leukodystrophy | Adrenoleukodystrophy, X-linked | Lattice Corneal Dystrophy | Silicosis | 3-methylglutaconic Aciduria | Mitochondrial DNA Depletion Syndrome 13 | Retinal Telangiectasia | Osteopetrosis | Hypokalemic Periodic Paralysis | Thrombophilia | Toxoplasmosis | Compartment Syndrome | Myelodysplasia | Macrophagic Myofasciitis | Hereditary Hemorrhagic Telangiectasia Type 2 | Partington Syndrome | Rhabdomyosarcoma, Embryonal | Juvenile Xanthogranuloma | Polycystic Kidney, Autosomal Recessive | Antley-Bixler Syndrome | Angioedema | Neurocutaneous Melanocytosis | Thyroiditis | Castleman Disease | Keratosis, Seborrheic | Urethritis | Obsessive-compulsive Disorder | Hypertensive Retinopathy | Osteochondroma | Renal Hypouricemia | Erythema Nodosum | Periventricular Leukomalacia | Tendinopathy | Trimethylaminuria | Lysosomal Acid Lipase Deficiency | Congenital Myopathy | Microcephaly | Zollinger-Ellison Syndrome | Galactosemia | Holoprosencephaly | Familial Partial Lipodystrophy | Rhabdomyosarcoma | CREST Syndrome | Hemochromatosis | Fraser Syndrome | Hyperostosis | Chondromyxoid Fibroma | Hyperuricemic Nephropathy, Familial Juvenile | Spinocerebellar Ataxia Type 23 | Coronary Restenosis | Keratopathy | Prolidase Deficiency | Angioimmunoblastic T-cell Lymphoma | Muir-Torre Syndrome | Adenocarcinoma | Jalili Syndrome | H Syndrome | Seminoma | Okihiro Syndrome | Prolactinoma | Sweet Syndrome | Lichen Planus | Atrial Septal Defect | Autosomal Recessive Bestrophinopathy | Alpha-1 Antitrypsin Deficiency | Hamartoma | Blastoma, Pleuropulmonary | Duchenne Muscular Dystrophy | Kabuki Syndrome 2 | Paraganglioma | Cyst | Pregnancy, Ectopic | Bare Lymphocyte Syndrome | Glycogen Storage Disease | Esthesioneuroblastoma | Protein S Deficiency | Malaria | Megalencephaly | Richter's Syndrome | LEOPARD Syndrome | Myoclonus | Hyperparathyroidism-jaw Tumor Syndrome | Diabetes Gestational | Sarcoma | Vitreoretinal Degeneration, Snowflake Type | Apert Syndrome | Behcet's Disease | LMNA-related Congenital Muscular Dystrophy | Central Retinal Artery Occlusion | Episodic Ataxia Type 1 | Amyloidosis | Corticobasal Syndrome | Huntington's Disease | Citrullinemia | Imerslund-Grasbeck Syndrome | Lateral Meningocele Syndrome | Giant Cell Glioblastoma | Zellweger Syndrome | Vasculitis | Klippel-Feil Syndrome | Sleep Apnea | Cannabis Abuse | Japanese Encephalitis | Thrombocytopenia | AIDS | Dyskeratosis Congenita | Muckle-Wells Syndrome | Strabismus | Transcobalamin Deficiency | Neurotoxicity | Hypertension | Adenomatoid Tumor | Sturge-Weber Syndrome | Opisthorchiasis | Sulfite Oxidase Deficiency | Medulloblastoma | Acute Coronary Syndrome | Aneurysm, Abdominal Aortic | Waardenburg Syndrome Type 1 | Wolff-Parkinson-White Syndrome | Progressive Familial Intrahepatic Cholestasis Type 2 | Nephroblastoma | Sleep Disorder | Vogt-Koyanagi-Harada Syndrome | Dermatitis Herpetiformis | Cardiomyopathy, Dilated, 1L | Pyloric Stenosis, Infantile Hypertrophic | Blue Nevus | Erythematotelangiectatic Rosacea | Glioma | Endometrial Hyperplasia | Ameloblastic Carcinoma | Mumps | Sarcoma, Ewing | Endometritis | Babesiosis | Hypopigmentation | Agnathia-Otocephaly Complex | Trigonocephaly | Waardenburg Syndrome Type 2A | Netherton Syndrome | Lennox-Gastaut Syndrome | Benign Familial Pemphigus | Generalized Epilepsy With Febrile Seizures Plus | Peritonitis | Astigmatism | Hypotonia-cystinuria Syndrome | Methemoglobinemia | Neuronal Ceroid Lipofuscinosis | Glioblastoma | Moyamoya Disease | Emery-Dreifuss Muscular Dystrophy | Amblyopia | Parkinson Disease 6, Autosomal Recessive Early-onset | Colitis, Lymphocytic | Thymoma, Malignant | Angina Pectoris | Nephronophthisis | Primary Familial Brain Calcification | Retinal Degeneration | Avellino Corneal Dystrophy | Craniosynostosis | Proximal Symphalangism | Farber Disease | Malonyl-CoA Decarboxylase Deficiency | Epidermolysis Bullosa Dystrophica | Connective Tissue Disorders | Necrobiosis Lipoidica | X-linked Myotubular Myopathy | Adrenal Insufficiency | Chronic Neutrophilic Leukemia | Blepharo-cheilo-odontic Syndrome | Duodenal Atresia | Adult Polyglucosan Body Disease | Asthma, Exercise-induced | Pancreatitis, Chronic | Pemphigus Vulgaris | Hyperhomocysteinemia | Double Outlet Right Ventricle | Weill-Marchesani Syndrome | Polyneuropathy | Pancreatitis | Osteoarthritis | Cri-du-chat Syndrome | Mast Cell Leukemia | Lipodystrophy | Congenital Heart Block | Optic Neuritis | Hyperinsulinemia | Congenital Central Hypoventilation Syndrome | Gastroenteritis | Haim-Munk Syndrome | Hypertensive Nephropathy | Phenylketonuria II | Twin-to-twin Transfusion Syndrome | Senior-Loken Syndrome | Placenta Previa