Vogt-Koyanagi-Harada Syndrome

About the Disease
Vogt-Koyanagi-Harada Disease, also known as uveomeningoencephalitic syndrome, is related to uveitis and pars planitis. An important gene associated with Vogt-Koyanagi-Harada Disease is PTPN22 (Protein Tyrosine Phosphatase Non-Receptor Type 22), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Bevacizumab and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and retina, and related phenotypes are sensorineural hearing impairment and cognitive impairment

Common Targets
CCDC26 | Tyrosine-Protein Kinases Src (nonspecified subtype) | LINC01147 | LINC01697 | CCR6 | RSBN1 | LINC01950 | LOC107986764 | ATG7 | LINC02511 | CFI | LCK | HLA-A | ETS2-AS1 | HCP5 | LINC02288 | LINC02270 | LOC105375523 | SLC39A11 | LOC107987121 | TRAF5 | DAP | NRAD1 | LOC105370982 | TBX21 | G3605 | CD40 | NOS3 | LOC105371006 | CD44 | DGUOK-AS1 | LINC02888 | ATG5 | IL10 | ATG16L1 | DCDC2C | LOC105369325 | JAKMIP1-DT | LINC02964 | LINC01121 | LINC01484 | REL-DT | CEP43 | LOC105375911 | cAMP-Dependent protein kinase (PKA) | LOC105369568 | TEK | SPATA13 | WAKMAR2 | MAP4K4 | MIR182 | LINC01019 | LINC01104 | CAVIN1 | IFNG | MAP4K1 | SHISA9 | NOS2 | TNFAIP3 | JAK2 | TIMMDC1 | LOC107984118 | ATG2A | NADSYN1 | RDUR | LOC102724900 | LOC105369735 | LOC105374364 | LINC02513 | LINC01194 | LOC285626 | PTPN22 | GPR19 | JAK1 | LINC02128 | TEX53 | LINC00921 | MIR146A | MIF | IL4 | LINC01378 | CLEC16A | HLA-DQB1 | LOC105371887 | HLA-C | GATA3 | BSN | LINC02253 | CCL2 | LINC02162 | LINC01187 | LOC105376481 | TGFB1 | LOC105369850 | MMP2-AS1 | LINC00578 | LOC107984903 | LINC01475 | G6774 | TNIP1 | TAP1 | LINC02127 | LOC105376626 | IL23R | ATG10 | LINC03016 | MTUS1-DT | HCG22 | TRAF3IP2 | FOXP3 | HLA-DRB1 | RORC | LINC02405 | LOC105379031 | HLA-B | SPP1 | ETS1 | ULK1 | BSN-DT | TSC1 | LINC02126 | ABL2 | LINC02506 | PVT1 | LOC100506023 | TRD-AS1 | LOC101927745 | C1orf141

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