Keratoacanthoma

About the Disease
Keratoacanthoma, also known as well-differentiated squamous cell carcinoma, is related to muir-torre syndrome and cystadenocarcinoma, and has symptoms including exanthema and pruritus. An important gene associated with Keratoacanthoma is NOTCH1 (Notch Receptor 1), and among its related pathways/superpathways are ERK Signaling and Disease. The drugs Lidocaine and Anesthetics, Local have been mentioned in the context of this disorder. Affiliated tissues include skin, tongue and lymph node, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Common Targets
CCDC17 | TGFBR1 | MAP3K11 | PVR | NRAS | HRAS

Note: If you'd like to get a target analysis report for Keratoacanthoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Keratoacanthoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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