Disease

Hyperuricemia

About the Disease
Hyperuricemia, also known as blood urate raized, is related to hyperuricemia, hprt-related and tubulointerstitial kidney disease, autosomal dominant, 1, and has symptoms including cachexia, cyanosis and dyspnea. An important gene associated with Hyperuricemia is UMOD (Uromodulin), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Levoleucovorin and Mecobalamin have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and liver, and related phenotypes are renal/urinary system and homeostasis/metabolism

Common Targets
ASGR1 | Asialoglycoprotein Receptor (ASGPR) (nonspecified subtype) | SLC5A2 | G114548 | SLC28A2 | CTNNB1 | SOS2 | IL37 | Protein Phosphatase 2A | IRF1 | IL1B | PDZK1 | SLC22A1 | PAX2 | G3620 | SLC17A3 | EPHX2 | SCD | Cholesterol esterase (nonspecified subtype) | TGFB1 | PPARA | SLC22A12 | KHK | TYR | G7099 | ADORA1 | Protein Tyrosine Phosphatase (PTP) (nonspecified subtype) | NAT1 | HMGCR | COMT | G23411 | GABA(A) receptor | Adenosine deaminase (nonspecified subtype) | TRPV2 | ADA | DNA Topoisomerase II (nonspecified subtype) | GUSB | GCKR | DPP4 | AKR1B1 | XDH | SLC22A2 | SLC17A4 | FCGR3A | ACHE | PPARG | SLC17A1 | PNP | G9429 | AKR1C3 | NR1H4 | G3630 | GNRHR | SERPINH1 | CARMIL1 | Mitogen-Activated Protein Kinase (nonspecified subtype) | ACACB | G4318 | CYP2C9 | A1CF | P2RY14 | SLC5A1 | AKR1B10 | SLC2A9 | IL2 | GAA | MMP2 | G4233 | P2RX7 | G5743 | IFNG | HNF4G | REN | ABCC1 | ABCC4 | APOE | DNA-Dependent Protein Kinase (DNA-PK) | LDHD | G7124 | MTHFR | PRPS1 | IL10 | SLC22A11

疾病靶点研报
Hyperuricemia

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