Macular Degeneration

About the Disease
Macular Degeneration, Age-Related, 1, also known as macular degeneration, is related to macular degeneration, age-related, 4 and retinoschisis 1, x-linked, juvenile, and has symptoms including vision loss, angina pectoris and tremor. An important gene associated with Macular Degeneration, Age-Related, 1 is HMCN1 (Hemicentin 1), and among its related pathways/superpathways is Complement cascade. The drugs Bevacizumab and Verteporfin have been mentioned in the context of this disorder. Affiliated tissues include Eye, and related phenotypes are macular hemorrhage and macular degeneration

Common Targets
SERPINF1 | ATF6B | Proteasome Complex | G10413 | DIAPH2 | BIRC2 | REST | TIMP3 | G7422 | CETP | ITGAM | LPL | TOMM40 | OTX2 | PARP3 | COL8A1 | HLA-DQB1 | G596 | CTNNB1 | FADS2 | SCN10A | CFB | IL17RC | Integrin alphaMbeta2 (MAC-1) Receptor | G3576 | CRBN | GUCY2D | IFNB1 | SKIC2 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | KDR | FOXO1 | CFP | Carbonic Anhydrase (nonspecified subtype) | TLR3 | CFI | HFE | IL1B | FSCN1 | Phosphodiesterase 1 (PDE1) (nonspecified subtype) | G6774 | ERCC6 | SLC16A8 | TNFRSF10A | NPC1L1 | PRPH2 | F13B | HDAC6 | RASGRF1 | CFD | ALDH3A2 | MRPL10 | Inhibitor of Apoptosis Proteins (IAPs) (nonspecified subtype) | Integrin alphavbeta3 (vitronectin) receptor | FZD4 | CFHR1 | SCARB1 | SMOC2 | RHO | CRX | LRP5 | MUTYH | TGFB1 | Matrix Metalloproteinase (MMP) (nonspecified subtype) | G1432 | FPR1 | FBN2 | TF | Integrin Receptor (nonspecified subtype) | SIX6 | MIR100HG | SYN3 | HTRA1 | G7099 | VASH1 | GUCA1A | TNFRSF10A-DT | BAD | CFHR4 | TOP1 | NOTCH4 | IKZF1 | CFHR5 | FSCN2 | ELOVL4 | OGG1 | KIT | B3GLCT | CHRNA7 | ABCA1 | ITGB2 | PRPF31 | BRD4 | ANGPT2 | MDM1 | CCR2 | NELFE | SOD2 | CDK9 | P2RX4 | ABCA4 | LOXL1 | PYGM | IRAK4 | PPARD | SPRYD7 | C1orf167 | G142 | HGS | SLC23A1 | COL1A2 | SUCNR1 | PDGFRB | G4170 | TGFBR1 | COL10A1 | IMPG1 | ADAMTS9-AS2 | ABCG8 | STK19 | CACNG3 | ARMS2 | PPARG | CSNK1A1 | LIPC | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | FBLN5 | PRDM13 | ABCC6 | APOC1 | G3480 | ERCC2 | FLT4 | PLEKHA1 | Vascular endothelial growth factor receptor (VEGFR) (nonspecified subtype) | FRK | DXO | Transcriptional Enhancer Factor (TEAD) (nonspecified subype) | BEST1 | CRYBB1 | PROM1 | SLC2A1 | RAF1 | CRYBB2 | F2RL3 | FLT1 | PTGER1 | PAX6 | TEK | CDK8 | TNXB | G4318 | GC | PON1 | CRB1 | MCUB | EIF2AK3 | FCGR2A | GJD2 | C9 | CACNA1E | METAP2 | TIMP2 | ACTC1 | KLKB1 | SMUG1 | SCO2 | C3 | GRM4 | ROBO1 | CFH | NPC1 | MFSD8 | PARP2 | MMP2 | VEPH1 | Tubulin | TFR2 | NT5DC1 | VDR | P2RX7 | PLA2G12A | KRR1 | SERPING1 | CCL2 | CX3CR1 | CYP27B1 | G5743 | PTGFR | FKBPL | LOC101928635 | BIRC5 | RIPK1 | RP1L1 | CYP46A1 | APOE | FADS1 | UNG | GAS6 | NR2F6 | MTR | PDGFRA | EPAS1 | GLP1R | LINC00243 | MYRIP | METTL1 | PTGER2 | MTHFR | FLT3 | RAD51B | CDK19 | C2

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