Combined Pituitary Hormone Deficiency

About the Disease
Pituitary Hormone Deficiency, Combined, 2, also known as panhypopituitarism, is related to pituitary hormone deficiency, combined or isolated, 1 and panhypopituitarism, x-linked. An important gene associated with Pituitary Hormone Deficiency, Combined, 2 is PROP1 (PROP Paired-Like Homeobox 1), and among its related pathways/superpathways are Signal Transduction and Class A/1 (Rhodopsin-like receptors). The drugs Epitestosterone and Oxytocin have been mentioned in the context of this disorder. Affiliated tissues include pituitary, thyroid and brain, and related phenotypes are hypothyroidism and short stature

Common Targets
G4089 | PROKR2 | OTX2 | HESX1 | GLI2 | BMP4 | OTP | LHX2 | LHX4 | HHIP | NR4A1 | GNRH1 | EYA4 | CHD7 | FGF8 | FGFR1 | HMX2 | E2F4 | LHX3 | POU1F1 | RNPC3 | ALMS1 | CDON | PROP1 | SHH | ZIC2 | SEMA3A | HES1 | WDR11 | SRA1 | TSHZ1 | PCSK1

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