B-cell Chronic Lymphocytic Leukemia

About the Disease
Leukemia, Chronic Lymphocytic, also known as chronic lymphocytic leukemia, is related to richter's syndrome and chronic lymphocytic leukemia/small lymphocytic lymphoma, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Leukemia, Chronic Lymphocytic is TP53 (Tumor Protein P53), and among its related pathways/superpathways are miRNA regulation of DNA damage response and DNA damage response (only ATM dependent). The drugs Valganciclovir and Ofatumumab have been mentioned in the context of this disorder. Affiliated tissues include Blood, and related phenotypes are cellular immunodeficiency and chronic lymphatic leukemia

Common Targets
CCL26 | CCR6 | PIK3CD | IKZF1 | TNFSF13 | G6352 | BCR | CCR4 | G4609 | CCR7 | TNFSF13B | FCGR3A | CCL7 | CCL8 | MS4A1 | CD22 | CCL11 | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | G7422 | CCR8 | TLR9 | CCL13 | CCL1 | CCR9 | IKZF3 | HEATR9 | CCR1 | ROR1 | LYN | FCGR2A | Ikzf1 | CCL18 | CRBN | G7124 | CCL20 | FYN | CD28 | CD160 | PIK3CG | DKK4 | CD19 | G7157 | ABL1 | G673 | FGF2 | CD37 | CCL24 | AMP-activated protein kinase (AMPK) | BTK | TNFRSF13B | G29126 | CAT | PLCG2 | CCR3 | CD3 Complex (T Cell Receptor Complex) | MYD88 | MALT1 | GHSR

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