Antithrombin III Deficiency

About the Disease
Antithrombin Iii Deficiency, also known as hereditary antithrombin deficiency, is related to hemophilia and cerebral sinovenous thrombosis. An important gene associated with Antithrombin Iii Deficiency is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Heparin, bovine and Calcium heparin have been mentioned in the context of this disorder. Affiliated tissues include bone, liver and bone marrow, and related phenotypes are reduced antithrombin iii activity and reduced antithrombin antigen

Common Targets
ALG12 | F2 | IDI2 | SERPINC1 | SLC5A9 | PMM2

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