Borderline Personality Disorder

About the Disease
Borderline Personality Disorder is related to schizotypal personality disorder and bulimia nervosa. An important gene associated with Borderline Personality Disorder is SLC6A4 (Solute Carrier Family 6 Member 4), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Fluoxetine and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include brain, amygdala and cortex, and related phenotypes are no effect and no effect

Common Targets
GATA4 | HTR1A | Kainate Receptor (GluR) (nonspecified subtype) | PTPN7 | Voltage-Gated Sodium Channel Complex | Sodium channel (nonspecified subtype) | TAAR5 | MCF2 | CACNA1C | Opioid receptor (nonspecified subtype) | APBA3 | OPRD1 | HTR2A | NINJ2 | SLC6A4 | FKBP5 | APBA2 | HLCS | KDM1A | VIPR2 | KCNQ1 | DDIT3 | CA2 | TPH1 | G7099 | MAOB | ADRA1B | ANK3 | OPRM1 | BDNF | OPRK1 | DRD2 | MIR4761 | Glutamate Receptor Ionotropic AMPA Receptor | NRXN3 | COMT | NR3C1

Note: If you'd like to get a target analysis report for Borderline Personality Disorder, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Borderline Personality Disorder at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Brachydactyly | Liebenberg Syndrome | Myelomeningocele | Retinal Degeneration | Nail-Patella Syndrome | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Ornithine Transcarbamylase Deficiency | Congestive Heart Failure | Mannosidase Deficiency Diseases | Photosensitivity | Congenital Myopathy | Pemphigus Foliaceus | Spastic Paraplegia Type 7 | Melanoma, Uveal | Craniometaphyseal Dysplasia | Hypereosinophilic Syndrome | Gestational Trophoblastic Disease | ADNP Syndrome | Encephalopathy | Hemolytic Anemia | Methemoglobinemia | Thyroid Dyshormonogenesis | Lattice Corneal Dystrophy Type 1 | Optic Nerve Diseases | Scleroderma, Diffuse | Cardiomyopathy, Peripartum | Gardner Syndrome | Hemimegalencephaly | 3C Syndrome | Calcium Pyrophosphate Deposition Disease | Acrodysostosis | Craniolenticulosutural Dysplasia | Alkaptonuria | Niemann-Pick Disease | Spinocerebellar Ataxia | Hyperferritinemia-cataract Syndrome | Intracranial Hypertension | Cellulitis | Osteomyelitis | Eclampsia | Panniculitis | Primary Ovarian Insufficiency | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Schizencephaly | Riboflavin Transporter Deficiency Neuronopathy | Senior-Loken Syndrome | Granular Corneal Dystrophy Type 1 | Heart Block | Wagner Disease | Renal-hepatic-pancreatic Dysplasia | Osteogenesis Imperfecta Type IV | Coenzyme Q10 Deficiency | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Schwartz-Jampel-Aberfeld Syndrome | Thrombasthenia | Thyrotoxic Periodic Paralysis | Corneal Neovascularization | Acute Leukemia | Chronic Beryllium Disease | Adenoid Cystic Carcinoma | Lesch-Nyhan Syndrome | Spinocerebellar Ataxia Type 40 | Sengers Syndrome | Autoimmune Autonomic Ganglionopathy | Stuve-Wiedemann Syndrome | Meningitis | Retinitis | Castleman Disease | Marshall-Smith Syndrome | Erythromelalgia | Vascular Calcification | Myopia | Vulvovaginitis | Spinocerebellar Ataxia Type 5 | Tyrosinemia Type 2 | Lattice Corneal Dystrophy | Hypertelorism | Hereditary Coproporphyria | Congenital Dyserythropoietic Anemia Type 4 | Hypertension | Diabetic Neuropathy | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Leri-Weill Dyschondrosteosis | Deafness, Dystonia, And Cerebral Hypomyelination | Fowler's Syndrome | Pontocerebellar Hypoplasia Type 2 | Primary Cutaneous Amyloidosis | Familial Exudative Vitreoretinopathy | Neurofibroma | Methemoglobinemia Type IV | Bursitis | McKusick Type Metaphyseal Chondrodysplasia | Best Macular Dystrophy | Acne | Joubert Syndrome 2 | X-linked Charcot-Marie-Tooth Disease | Treacher Collins Syndrome | Heterotaxy | Hepatoblastoma | Toxic Epidermal Necrolysis | Familial Thoracic Aortic Aneurysm | Recurrent Respiratory Papillomatosis | Combined Malonic And Methylmalonic Acidemia | Ophthalmoplegia | Atrial Septal Defect | Camptocormia | Pneumonia, Bacterial | Orotic Aciduria | Aarskog-Scott Syndrome | Chondromyxoid Fibroma | Microvillus Inclusion Disease | Oligoasthenoteratozoospermia | Hepatic Veno-occlusive Disease | Neuroblastoma | Pseudohermaphroditism | Myoclonus-dystonia Syndrome | Porphyria | Vogt-Koyanagi-Harada Syndrome | Paraganglioma, Carotid Body | Myocarditis | Lichen Planus | Kallmann Syndrome | Axenfeld-Rieger Syndrome | Zellweger Syndrome | Hypogonadism | Cranioectodermal Dysplasia | Cocaine-Related Disorders | Rubeosis Iridis | Analgesia | Hypothalamic Obesity | Nasodigitoacoustic Syndrome | Hashimoto Thyroiditis | Brenner Tumor | Congenital Primary Aphakia | Greenberg Dysplasia | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Measles | Interstitial Lung Diseases | Ureteropelvic Junction Obstruction | Von Willebrand Disease | Hemochromatosis | Papillon-Lefevre Syndrome | Cancer, Kidney | Larsen Syndrome | Colon Adenoma | Myelitis, Transverse | Heart Failure | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Batten Disease | COACH Syndrome | Optic Neuropathy, Anterior Ischemic | Overactive Bladder | AIDS | Apraxia | Lymphopenia | CDKL5 Deficiency Disorder | Migraine | Carbamoyl Phosphate Synthetase I Deficiency | Proteasome-associated Autoinflammatory Syndrome 2 | Glutathione Synthetase Deficiency | Osteosclerosis | Fibrosis | Spondyloperipheral Dysplasia | Multiple Sclerosis, Primary Progressive | Early Infantile Epileptic Encephalopathy | Hennekam Lymphangiectasia-lymphedema Syndrome | Hypospadias | Ventricular Septal Defect | Lamellar Ichthyosis | Pierpont Syndrome | Sleep Apnea, Obstructive | Nanophthalmos | Glanzmann Thrombasthenia | Situs Inversus | Waldenstrom Macroglobulinemia | Gingivitis | Wolfram Syndrome 2 | Primary Hyperoxaluria | Greig Cephalopolysyndactyly Syndrome | Diabetes Insipidus | Cholangitis | Martsolf Syndrome | Asperger Syndrome | Porphyria, Variegate | Polycystic Kidney, Autosomal Dominant | Hyperlipidemia Type V | Myelofibrosis | Hypertension, Portal | Diverticulitis | Encephalopathy, Glycine | Budd-Chiari Syndrome | Charcot-Marie-Tooth Disease, Type 1A | Bloom Syndrome | Hyperglycemia | Bulimia Nervosa | Hydrocephalus | Periodontitis | Dysequilibrium Syndrome | Hypotrichosis | Neuroma | Charcot-Marie-Tooth Disease Type 4 | Osteoporosis | Periventricular Nodular Heterotopia | Donnai-Barrow Syndrome | Toxoplasmosis | Acute Generalized Exanthematous Pustulosis | Diabetic Macular Edema | Barrett Esophagus | Endometritis | Pseudohypoparathyroidism Type 1B | Hydronephrosis | Ectopia Lentis, Isolated, Autosomal Recessive | Vertigo | Meniere's Disease | Stromal Corneal Dystrophy | Acute Anterior Uveitis | Acute Motor Axonal Neuropathy | Peutz-Jeghers Syndrome | Osteochondrosis | Hereditary Inclusion Body Myopathy | Spinal Muscular Atrophy Type 2 | Charcot-Marie-Tooth Disease Type 2D | Bone Marrow Necrosis | Blepharophimosis Syndrome | Psoriasis | Encephalopathy, Ethylmalonic | Mood Disorder | Scleroderma | Facioscapulohumeral Muscular Dystrophy Type 2 | Malonyl-CoA Decarboxylase Deficiency | Leri Pleonosteosis | Scapuloperoneal Spinal Muscular Atrophy | Congenital Hemolytic Anemia | Paracoccidioidomycosis | Familial Advanced Sleep Phase Syndrome | 3-methylglutaconic Aciduria | Fontaine Progeroid Syndrome | Postpoliomyelitis Syndrome | Pycnodysostosis | Ameloblastoma | Essential Fructosuria | Muscle Wasting | Geleophysic Dysplasia | Peripheral T-cell Lymphoma | Erythematotelangiectatic Rosacea | Focal Cortical Dysplasia Type 2 | Prostatitis | Turner's Syndrome | Lymphedema | Atelosteogenesis Type 1 | Aceruloplasminemia | SAPHO Syndrome | Hereditary Sensory Neuropathy Type 1 | Hereditary Neuropathy With Liability To Pressure Palsies | Gerstmann-Straussler-Scheinker Syndrome | Withdrawal Syndrome | Vestibular Disease | Aspergillosis | Malignant Peripheral Nerve Sheath Tumor | Persistent Fetal Circulation | Crimean-Congo Hemorrhagic Fever | Sporadic Inclusion Body Myositis | Antley-Bixler Syndrome | Protein S Deficiency | Waardenburg Syndrome Type 2A | Inborn Errors Of Metabolism | Nephrotic Syndrome Type 1 | Adenoma, Pituitary | Tonsillitis | Pyoderma Gangrenosum | Meningeal Melanocytoma | Anorectal Fistula | Diabetes Gestational | Lymphoproliferative Disorders | Liddle Syndrome | Membranous Nephropathy | Spondylolisthesis | Hyperparathyroidism, Secondary | Hepatitis D | Lissencephaly 2 | Smith-Magenis Syndrome | Asplenia | Leiomyoma | Encephalocele | Ovarian Sex Cord-stromal Tumor | Rolandic Epilepsy | Tenosynovial Giant Cell Tumor | Chordoid Glioma | Non-Langerhans Cell Histiocytosis | Choroideremia | Skin Fragility-woolly Hair Syndrome | Gout | Dementia | Arthropathy | Babesiosis | HUPRA Syndrome | Congenital Heart Defects | Cystitis | Impetigo | Cancer, Breast | Avellino Corneal Dystrophy | Familial Hemiplegic Migraine | Hypoplastic Left Heart Syndrome | D-2-Hydroxyglutaric Aciduria | Creutzfeldt-Jakob Disease | Frank-ter Haar Syndrome | Corneal Ulcer | Cannabis Abuse | Charcot-Marie-Tooth Disease, Type 6 | Inflammatory Myopathy | Gynecomastia | Cohen Syndrome | Woodhouse-Sakati Syndrome | Nephrocalcinosis | Diffuse Intrinsic Pontine Glioma | Desbuquois Syndrome | Meningococcal Infections | Sarcoidosis, Pulmonary | Bacterial Meningitis | Hemolytic Uremic Syndrome, Atypical | Bullous Pemphigoid | Phosphoglycerate Dehydrogenase Deficiency | Eosinophilic Asthma | Cholera | Agammaglobulinemia | Necrotizing Autoimmune Myopathy | Hyperlipidemia, Familial Combined | Hypoparathyroidism | Obsessive-compulsive Disorder | Mitochondrial Myopathy | Ileitis | Familial Cerebral Amyloid Angiopathy | Mohr-Tranebjaerg Syndrome | Cardiofaciocutaneous Syndrome | Autosomal Recessive Spastic Paraplegia Type 75 | Crigler-Najjar Syndrome | Leber Hereditary Optic Neuropathy | Cancer, Skin | Hydrocephalus, Normal Pressure | Renal Oncocytoma | Congenital Muscular Dystrophy | Pancreatitis | Trichuriasis | Norrie Disease | Yellow Fever | Inflammatory Bowel Disease | Iron Overload | Focal Dermal Hypoplasia | Meconium Ileus | Galloway-Mowat Syndrome | Blepharospasm | HIBCH Deficiency | Parkinson Disease 6, Autosomal Recessive Early-onset | Xeroderma Pigmentosum Variant Type | Oral Lichen Planus | Meleda Disease | Bietti Crystalline Dystrophy | Myoclonus | Polycystic Liver | Hemophagocytic Lymphohistiocytosis | Cleidocranial Dysplasia | Non-epidermolytic Palmoplantar Keratoderma | Tremor | Cardiomyopathy, Hypertrophic | Diarrhea | Angiosarcoma | Epithelial-myoepithelial Carcinoma | Ligneous Conjunctivitis | Retinal Diseases | Chondrodysplasia Punctata 2, X-linked Dominant | IgA Nephropathy | Rotor Syndrome | Infantile Nephropathic Cystinosis | Ocular Hypertension | Keratoacanthoma | Homocystinuria | Klinefelter Syndrome | Primary Biliary Cholangitis | Fibronectin Glomerulopathy | Hepatitis, Autoimmune | Onchocerciasis | Chronic Myelomonocytic Leukemia | Atelosteogenesis Type 2 | Liver Diseases | Spinal Muscular Atrophy | Pituitary Dwarfism | Skin Carcinoma | Hypervalinemia | Spinocerebellar Ataxia Type 21 | Peripheral Neuropathy | Epidermolysis Bullosa | Kindler Syndrome | Rhabdomyosarcoma, Alveolar | Abetalipoproteinemia | T-cell Chronic Lymphocytic Leukemia | Rhabdoid Tumor | Ocular Albinism Type 1 | Endometriosis | DICER1 Syndrome | Spinocerebellar Ataxia Type 42